Recent decades have witnessed accelerated climate changes across the Qinghai-Tibet Plateau (QTP) and elevated socioeconomic exposure to meteorological hazards. The QTP is called the “the third pole”, exerting remarkable impact on environmental changes in its surrounding regions. While few reports are available for addressing multi-hazard risks over the QTP, we develop an integrated indicator system involving multiple meteorological hazards, i.e., droughts, rainstorms, snowstorms and hailstorms, investigating the spatiotemporal patterns of major hazards over the QTP. The hazard zones of droughts and rainstorms are identified in the southern Gangdise Mountains, the South Tibet Valley, the eastern Nyenchen-Tanglha Mountains, the Hengduan Mountains and West Sichuan Basin. Snowstorm hazard zones distribute in the Himalayas, the Bayan Har Mountains and the central Nyenchen-Tanglha Mountains, while hailstorm hazard zones cluster in central part of the QTP. Since the 21st century, intensified rainstorms are detectable in the densely populated cities of Xining and Lhasa and their adjacent areas, while amplified droughts are observed in grain production areas of the South Tibet Valley and the Hengduan Mountains. Snowstorm hazards show large interannual variations and an increase in pastoral areas, although the overall trend is declining slightly. The frequency of hailstorms gradually decreases in human settlements due to thermal and landscape effects. Mapping meteorological hazards regionalization could help to understand climate risks in the QTP, and provide scientific reference for human adaptation to climate changes in highly sensitive areas.