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Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib
Published Web Location
http://europepmc.org/articles/PMC3429780?pdf=renderNo data is associated with this publication.
Abstract
Poly(ADP-ribose) polymerase (PARP) is an enzyme involved in DNA repair. PARP inhibitors can act as chemosensitizers, or operate on the principle of synthetic lethality when used as single agent. Clinical trials have shown drugs in this class to be promisin
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