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NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.

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http://europepmc.org/articles/PMC3622749?pdf=render
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Abstract

The activation of NADPH oxidase has been implicated in NEFA-induced beta cell dysfunction. However, the causal role of this activation in vivo remains unclear. Here, using rodents, we investigated whether pharmacological or genetic inhibition of NADPH oxid

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