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Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects
- Kumar, Rajesh;
- Williams, L Keoki;
- Kato, Atsushi;
- Peterson, Edward L;
- Favoreto, Silvio;
- Hulse, Katie;
- Wang, Deli;
- Beckman, Kenneth;
- Thyne, Shannon;
- LeNoir, Michael;
- Meade, Kelley;
- Lanfear, David E;
- Levin, Albert M;
- Favro, David;
- Yang, James J;
- Weiss, Kevin;
- Boushey, Homer A;
- Grammer, Leslie;
- Avila, Pedro C;
- Burchard, Esteban G;
- Schleimer, Robert
- et al.
Published Web Location
https://doi.org/10.1016/j.jaci.2012.04.047Abstract
A BAFF polymorphism is associated with asthma exacerbations and serum BAFF levels. BAFF expression in vivo increases in natural rhinovirus infection. BAFF may play a role in airway antiviral immunity and impact asthma exacerbation rates.
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