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Detection and Characterization of Enterovirus B73 from a Child in Brazil
- de Oliveira Ribeiro, Geovani;
- Luchs, Adriana;
- de Pádua Milagres, Flávio Augusto;
- Komninakis, Shirley Vasconcelos;
- Gill, Danielle Elise;
- Lobato, Márcia Cristina Alves Brito Sayão;
- Brustulin, Rafael;
- Chagas, Rogério Togisaki das;
- dos Santos Abrão, Maria de Fátima Neves;
- de Deus Alves Soares, Cassia Vitória;
- Witkin, Steven S;
- Villanova, Fabiola;
- Deng, Xutao;
- Sabino, Ester Cerdeira;
- Delwart, Eric;
- da Costa, Antonio Charlys;
- Leal, Élcio
- et al.
Published Web Location
https://doi.org/10.3390/v11010016Abstract
Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a child with acute gastroenteritis living in a rural area in Northern Brazil. The subject was not infected with any known enteric pathogens such as norovirus, rotavirus, helminths, or enteric bacteria. Analysis of the nearly full-length TO-127 genome (6993 nt) indicated a 74⁻75% nucleotide similarity with EV-B73 strains from other countries. Evolutionary analysis suggests that B73 is endemic and widespread.
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