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Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Published Web Location

http://europepmc.org/articles/PMC4502749?pdf=render
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Abstract

© Martina Haller, Andreas K Hock, Evangelos Giampazolias, Andrew Oberst, Douglas R Green, Jayanta Debnath, Kevin M Ryan, Karen H Vousden, and Stephen W G Tait.During macroautophagy, conjugation of ATG12 to ATG5 is essential for LC3 lipidation and autophago

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