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Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

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http://europepmc.org/articles/PMC4195823?pdf=render
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Abstract

© 2014 Lu et al.The ubiquitin protein ligase anaphase-promoting complex or cyclosome (APC/C) controls mitosis by promoting ordered degradation of securin, cyclins, and other proteins. The mechanisms underlying the timing of APC/C substrate degradation are

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