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Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement
Published Web Location
http://europepmc.org/articles/PMC4382417?pdf=renderNo data is associated with this publication.
Abstract
We describe a general approach for refining protein structure models on the basis of cryo-electron microscopy maps with near-atomic resolution. The method integrates Monte Carlo sampling with local density-guided optimization, Rosetta all-atom refinement a
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