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Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

Published Web Location

http://europepmc.org/articles/PMC4909985?pdf=render
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Abstract

To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and detected 124 mosaic X events >2 Mb in 97 (0.2

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