Table 2. Comparison of clinicohistopathological findings between HALE and Kimura disease [2-6]
Clinico-histopathological findings |
Kimura disease |
Angiolymphoid hyperplasia with eosinophils |
Age Sex Race Clinical findings Size Site Depth Salivary gland attempt Renal attempt Adenomegaly Recurrence Histology Depth Neoangiogenesis, endothelial cells Mastocytes Germinal center Fibrosis Blood Eosinophilia IgE level |
3 first decades Male (85%) Oriental Bigger (2–10 cm) Head and neck Deep Common Common Common 15-40% Sub-cutaneous tissue Absent Present Usually present Marked Increased Increased |
Third to fifth decade Female (70%) White Smaller (0.2–6.0 cm) Head and neck Superficial Rare (5%) Rare Rare 30% Dermis, sub-cutaneous tissue Present Multiple Absent Absent Usually normal Low |