Table 2. Comparison of clinicohistopathological findings between HALE and Kimura disease [2-6]

 

 

Clinico-histopathological findings

Kimura disease

Angiolymphoid hyperplasia with eosinophils

 

Age

 

Sex

 

Race

 

Clinical findings

Size

Site

Depth

Salivary gland attempt

Renal attempt

Adenomegaly

 

Recurrence

 

Histology

 

Depth

Neoangiogenesis, endothelial cells

Mastocytes

Germinal center

Fibrosis

 

Blood

Eosinophilia

IgE level

 

 

3 first decades

 

 Male (85%)

 

Oriental

 

 

Bigger (210 cm)

Head and neck

Deep

Common

Common

Common

 

15-40%

 

 

 

Sub-cutaneous tissue

Absent

Present

 Usually present   

Marked     

 

 

Increased 

Increased

 

Third to fifth decade

 

Female (70%)

 

White

 

 

Smaller (0.26.0 cm)

Head and neck

Superficial

Rare (5%)

Rare

Rare

 

30%

 

 

 

Dermis, sub-cutaneous tissue

Present

Multiple

Absent

Absent

 

 

Usually normal

Low