Table 2: Data concerning treatment and outcome in 21 followed-up children with LAD
|
Patient |
Age |
Sex |
Dapsone (monotherapy) |
Dapsone + oral steroids |
Dapsone + Erythromycin (50mg/Kg/d) |
Amoxicillin |
Sulfamide ATB |
Duration of treatment |
Response to treatment (partial or complete healing) |
Flare under ttt |
Follow-up |
Recurrence |
|
1 |
6 |
M |
50 mg/d |
|
|
|
|
21 mths |
3 days |
1 episode |
2y |
No |
|
2 |
4 |
F |
|
|
|
|
1 g/d |
1 y |
|
|
2y |
No |
|
3 |
11 |
F |
50 mg/d |
|
|
|
|
4 mths |
23 days |
No |
6y |
No |
|
4 |
1.8 |
F |
75mg/d |
|
|
|
|
NP |
22days |
NP |
LF |
LF |
|
5 |
6 |
M |
|
50mg/d + 40mg/d |
|
|
|
9 mths |
15 days |
Yes |
9 mths |
No |
|
6 |
1. 5 |
M |
|
|
50mg/d |
|
|
2 mths |
Rapid response |
No |
LF |
LF |
|
7 |
2 |
M |
25mg/d |
|
|
|
|
NP |
? |
NP |
LF |
LF |
|
8 |
4. 5 |
M |
|
|
75mg/d |
|
|
6 mths |
24 days |
No |
4y |
No |
|
9 |
3 |
M |
|
|
25mg/d |
|
|
3 mths |
NP |
Yes |
3 mths |
LF |
|
10 |
4 |
M |
|
|
50mg/d |
|
|
one mth |
NP |
No |
3 mths |
LF |
|
11 |
15 |
M |
|
200mg/d + 30mg/d |
|
|
|
6 y |
11 days |
Yes |
11 y |
No |
|
12 |
8 |
M |
|
50mg/d+ 10 mg/d |
|
|
|
NP |
7 days |
No |
LF |
LF |
|
13 |
2..5 |
M |
|
50mg/d+15mg/d |
|
|
|
3 y |
Rapid response |
Yes |
3 y |
No |
|
14 |
1 |
M |
|
25mg/d+10mg/d |
|
|
|
9 mths |
8 days |
Yes |
9 mths |
No |
|
15 |
2 |
M |
|
25mg/d+10mg/d |
|
|
|
9 mths |
15 days |
Yes |
11 mths |
No |
|
16 |
3 |
F |
|
|
|
1g/d |
|
3 mths |
20 days |
yes |
3 mths |
Remission then LF |
|
17 |
12 |
F |
25 mg/d |
|
|
|
|
3 mth |
No |
Yes |
3 mths |
Continued to flare |
|
18 |
7 |
F |
|
25mg/d+ 25mg/d |
|
|
|
3 mths |
15 days |
No |
2 y |
Pruritus |
|
19 |
8 |
F |
50 mg/d |
|
|
|
|
1 year |
15 days |
No |
1. 5 y |
No |
|
20 |
1.5 |
M |
25 mg/d |
|
|
|
|
5 mths |
9 days |
No |
4 mths |
No |
|
21 |
11 |
M |
100 mg/d |
|
|
|
|
6 mths |
7 days |
No |
3 y |
No |
Abbreviations: y:years ; mth(s): month(s); NP: not precised; LF: lost to follow-up, ttt: treatment