1.      Hematological disorders

Monoclonal gammopathy of uncertain significance

Multiple myeloma

Lymphoma

Acute and chronic myelomonocytic leukemia

Chronic lymphatic leukemia

Idiopathic Bence-Jones proteinuria

Crioglobulinemia

2.      Casual associations

Ehlers-Danlos síndrome

Reumatoid arthritis

Diabetes

Pulmonar fibrosis

Leucocitoclasic vasculitis

Amiloidosis

Erythematous lupus

3.      Appereance after skin injury

Erytrhodermia

Atopic dermatitis

4.      Associated to high serum lipid levels or secondary to biliar cirrhosis or obstructive liver disease

5.      Idiopathic diffuse plane xanthoma