Table 1: Cutaneous sarcoidosis preceding development of neoplasia.
Reference |
Age |
Evidence of sarcoidosis |
Time |
Associated malignancy |
Atwood WG (1966) [21] |
49 BM |
LNp, lung, chest wall, spleen |
6 yr |
MF & lymphocytic lymphoma |
Asvesti C (1994) [22] |
52 F |
LNp, hilar LN, ACE lung (int) hepatomeg, Inc ESR |
~8 mo |
Sweat gland carcinoma |
Banno S (1992) [23] |
31 M |
LNp, muscle |
13 yr |
DLBCL |
Bessis D (1996) [24] |
35 F |
- |
27 yr |
MF and anaplastic large TCL (Ki 1+) |
Brechtel B (1996) [25] |
57 F |
- |
1 yr |
Breast cancer |
Cantwell AR (1982) [26] |
73 WF |
Lung (interstitial), ACE |
14 mo |
NHL (poor diff, immature), Lip BCC |
Caras W (2003) [27] Patient 1 |
32 BM |
Hilar LN, ACE |
6 yr |
HD (nodular sclerosis) |
Chao SC (2000) [28] Case 1 |
42 M |
Lung (interstit) |
14 yr |
CTCL |
Collet E (1992) [29] |
58 F |
Lung (?), cutaneous ( ?) |
7 yr |
Waldenstrom |
Corda L (1996) [30] |
65 F |
Eyes (b/l uveitis), bronchial, gastric |
7 yr |
Kaposi’s dx on the skin |
Diette KM (1984) [31] |
49 M |
Liver, BM |
1 yr |
Intracranial large-cell NHL |
Falchero L (1998) [32] |
74 F |
LNp, lung nodules |
3 yr |
CTCL |
Harada H (1994) [33] |
44 F |
Lung interstitial |
23 yr |
CTCL |
Hermann C (1980) [34] |
60 M |
Joints (knee) |
4.5 yr |
AML |
Karakantza M (1996) [35] |
34 BM |
LNp, hilar LN, monoarthritis, b/l keratoconjunctiv |
28 yr |
Extramedullary plasmacytoma |
Katz KA (2002) [36] |
66 F |
Skin |
3 mo |
MDS * granulomatous skin |
Keohane SG (1996) [37] |
36 M |
Hilar LN |
6 yr |
Low-grade NHL |
Maekawa Y (1993) [38] |
53 AF |
Hilar LN, lung (int), inc ACE |
6 mo |
ADK esophagus |
Maillard H (1998) [39] |
34 M |
- |
5 yr |
MF |
Mainguene C (1993) [40] |
31 F |
Arthralgia, ACE, LNp |
4 yr |
MF |
McFarland JP (1978) [41] |
47 BF |
LNp, hilar LN |
8 yr |
MF |
Morii S (1997) [42] |
61 F |
Inc ACE |
15 mo |
Gastric plasmacytoma |
Myerson RM (1971) [43] |
49 BM |
Hilar LN, p LN, lungs, liver, uveitis |
23 yr |
Hepatocellular carcinoma |
Noone PG (1993) [44] |
? |
Pulm (int), arthralgias |
3 yr |
NSCLC (ADK) |
Okada M (2000) [45] |
54 F |
P LN, hilar LN, uveitis |
2 mo |
Colon ADK + XP &SCC/BCC 6 mo before and coex with sarc. |
Oliwiecki S (1992) [46] |
49 M |
ACE |
3 yr |
NHL (palate) |
Raben AC (1961) [47] |
45 F |
N/A |
? |
NHL |
Robert C (1997) [67] |
35 F |
Mediast LN, lung (int), bronch epit |
27 mo |
Melanoma |
Roth D (1994) [48] |
31 BM |
Lung (int), eye, granul gastritis & proctitis |
19 yr |
Poorly diff stomach ADK |
Schiller G (2003) [49] |
71 F |
Lung(interstitial), ankle edema, also Eryth Nod |
18 mo |
Hairy-cell leukemia |
Sherertz EF (1986) [50] |
54 M |
Skin |
Shortly |
NHL (lymphocytic lymphoma) |
Serratrice J (2002) [51] 2 cases |
55 BF |
b/l eye (uveitis), ESR |
7 yr |
CMML |
62 WF |
Uveitis, skin |
5 yr |
CMML |
|
Simsek S (2002) [52] |
51 F |
Lung (int), liver, pLN |
7 yr |
HD |
Sorrells T (1997) [53] |
39 BM |
Hilar LN |
3 yr |
NHL (MF) |
Suarez-Vilela D (2003) [54] |
67 F |
Skin |
2 yr |
NHL (AILD-like T-cell lymphoma) |
Takada K (1993) [55] |
31 M |
Muscle, ACE |
23 yr |
NHL (supraclavicular LN) (T-cell diffuse large-cell) |
Terao S (1985) [56] |
55 F |
- |
8 yr |
NHL |
Todd RF (1980) [57] |
78 M |
Eye, neurop, hypercalc |
3 yr |
Prostate cancer |
Ueda T (1988) [58] |
54 F |
Lung, eye |
5 yr |
NHL |
VesteyJP (1993) [59] 2 cases |
66 M |
Skin, hematologic |
4.5 mo |
AML (through MDS) |
71 M |
Skin, hematologic |
4 mo |
MDS |
|
Zimmermann-Belsin (2000) [60] |
27M |
Skin, b/l hilar LN |
3 yr |
Thyroid papillary carcinoma |
|
||||
Present report (4 cases) |
64 F |
LNp, mediast LN, lung interstitial |
8 yr |
Breast cancer, colon cancer, renal cancer |
42 F |
LNp, arthritis |
4 yr |
Breast cancer (bilateral), SCC skin |
|
41 F |
Mediast LN, lung interstitial, |
5 yr |
Breast cancer (infiltrating ductal carcinoma) |
|
47 M |
Lung interstitial |
15 yr |
Prostate cancer |