Table 4.
Reference |
MHC Class I |
MHC Class II |
[29] |
HLA-Cw6, HLA-B13, HLA-B57 |
HLA-DR2 |
[30] |
HLA-B12, HLA-B17, HLA-Cw6 |
|
[31] |
HLA-Cs*602, HLA-B27 |
|
Table 4. Psoriasis is predominantly associated with MHC Class I proteins, supporting
the role of CD8+ T cells in psoriasis. (Recall that the CD8 molecule stabilizes the T cell
receptor/ antigen/ MHC Class I molecule complex allowing antigen-specific activation
of cytotoxic T cells.)