Clinical Stage

Type of Relapse

Relapse Rate

Reference

IA

L

0.45%

[Urist 1985; Schmid-Wendtner 2003]

[Balch 2001]?

LN

2%

[Rousseau 2003]

macroscopic = 2%

[Balch 1980 ; Balch 2001]

S

1.59%

[Kang 2005]?

(Calc Balch) [Balch 2001]

M

2.1%

[Balch 1980 ; Balch 2001]

IB

L

1.48% ↑

[Urist 1985; Schmid-Wendtner 2003] [Balch 2001]

LN

9%; ↑S

[Rousseau 2003]

macroscopic = 18.18%

[Balch 1980 ; Balch 2001]

S

3.16%↑

[Kang 2005] [Balch 2001]

M

6.52% ↑

[Balch 1980 ; Balch 2001]

IIA

L

4.86% ↑

[Urist 1985] [Balch 2001]

LN

24% ↑S

[Rousseau 2003]

macroscopic 45.53% ↑

[Balch 1980 ; Balch 2001]

S

7.16% ↑

[Kang 2005] [Balch 2001]

M

12.49% ↑

[Balch 1980 ; Balch 2001]

IIB

L

8.23% ↑

[Urist 1985] [Balch 2001]

LN

3.4% ↑S

[Rousseau 2003]

macroscopic 58.34%

[Balch 1980 ; Balch 2001]

S

9.00% ↑

[Kang 2005] [Balch 2001]

M

30.37%↑

[Balch 1980 ; Balch 2001]

IIC

L

13.2% ↑

[Urist 1985] [Balch 2001]

LN

53%; ↑S

[Rousseau 2003]

macroscopic 62%

[Balch 1980 ; Balch 2001]

S

8.95%

[Kang 2005] [Balch 2001]

M

72% ↑

[Balch 1980 ; Balch 2001]

IIIA

L

15.7% ↑

[Fincher 2003; Calabro 1989]

LN

14% ↓

[Pidhorecky 2001; Fincher 2003]

S

27% ↑

[Calabro 1989]

M

66.8%

[Calabro 1989]

IIIB

L

15.6%

[Calabro 1989]

LN

20.65% ↑

[Pidhorecky 2001] [Balch 2001]

S

17%

[Calabro 1989]

M

67.4% ↑

[Calabro 1989]

IIIC

L

15.6%

[Calabro 1989]

LN

28% after TLND ↑

[Pidhorecky 2001]

S

12.9%

[Calabro 1989]

M

76.7% ↑

[Calabro 1989]