Hurley Stage by Treatment->

Physical Finding↓

Stage I

Stage 2 (here combined therapy of agents listed must be considered)

Stage 3 (here combined therapy of agents listed must be considered)

Scarring, fibrosis, oval scars

ILK  

 ILK

 surgery, ILK

Dkin indurations non continuous

ILK ABC1,ABC2, TA

ILK,  TNFaB, ABC, DAP, IVAB

 ILK,ABC, TNFaB

Plaque-like indurations,

ILK ABC1, ABC 2

ILK  TNFa B, ABC

 ILK, IVAB, TNFaB

Ropelike scars,

ILK, ABC1-ABC2

 ILK, CO2 laser

 ILK, CO2 laser

Dermal contractures

ILK ABC1-ABC2

 ILK, ABC, TNFaB, IVAB

 ILK

Keloids painful

ILK, ABC1, ABC2

 ILK, ABC, IVAB, TAB, OCP, TNFaB, spironolactone

 TNFaB, ABC, ILK, IVAB

Abscesses superficial & deep, fistula

incision drainage, ILK,

ABC1, AB2, dapsone

 incision drainage, ILK, ABC, DAP, acitretin TNFaB, IVAB, THB

TNFaB, surgery, ABC as adjunct, ILK, IVAB, cyclosporine, TH

Inflammatory mediators

ILK, TNFa, ABC, DAP botulinum toxin

ILK, TNFaB, aABC, DAP, botulinum toxin, IVIG

ILK, TNFaB, ABC as adjunct, cyclosporine, botulinum toxin, IVIG

Edema independent of lympedema

compression, massage ABC

 compression, massage, ABC, TNFaB, IVAB

compression, massage, surgery ABC, TNFaB, IVAB, cyclosporine

Open ulcerations

Soothing emulsions, Skin barriers, topical antibiotics

Soothing emulsions, topical clindamycin, topical dapsone, ABC, TNFaB, THB, IVAB

surgery, soothing emulsions, topical clindamycin, topical dapsone, IVAB, TNaB, CO2 laser

Chronic sinuses

 Drainage, ILK, marsupialization, ABC

 Marsupialization, IVAB,DAP, surgery, CO2 laser

surgery, marsupialization, IVAB, CO2 laser, surgery with GCSF

Subcutaneous honeycombing

ILK, ABC

 ILK, ABC, surgery

 ILK, ABC,  TNFaB, cyclosporine

Frictional pain/shearing forces

weight loss, skin barrier devices & topicals

weight loss, skin barriers topicals, preparations, special bandages

weight loss, skin barriers, topicals, preparations,

Follicular occulsion

isotretinoin, acitretin,

acne surgery, ABC1, 1064nm laser

acitretin, acne surgery, ABC, surgery, isotretinoin if other treatments fail, ABC, TNFaB,

1064nm laser

acitretin, TNFaB acne surgery, ABC, surgery, 1064 nm laser

Rupture of follicules

 ILK, ABC1, ABC2,  topical clindamycin

topical dapsone

ILK, ABC, surgery, IVAB, TNFaB, DAP

ILK, ABC, IVAB

Topicals, surgery, cyclosporine

Acne Inversa

acitretin, , acne surgery, ABC1, ABC2

 acitretin, acne surgery, ABC,  istretinoin if other tx fail

isotretinoin acitretin, physical acne surgery, 1064 nm laser ery, ABC, TNFaB, IVAB,

Pyogenic granulomas

ILK, cyrotherapy, DAP, ABC1, ABC2

ILK, cyrotherapy, DAP, ABC,surgery, TNFaB

 ILK, cyrotherapy, dapsone, ABC,srgery, cyclosporine, TNFaB

Lymphedema

the use of compression and, at times, lymphatic massage, consults

the use of compression and, at times, lymphatic massage, vascular surgery or urology consultation

the use of compression and, at times, lymphatic massage, vascular surgery or urology consultation

.Lymphangiectasias

compression and, at times, lymphatic massage. consults

the use of compression and, at times, lymphatic massage, vascular surgery.OB or urology consultation

the use of compression and, at times, lymphatic massage. vascular surgery, OB or urology consultation

HS with menstrual flaring

OCP, spironolactone, Cyproterone acetate with ethinyloestradiol

OCP, spironolactone, Cyproterone acetate with ethinyloestradiol

leuprolide  acetate,flutamide,degarelix, gonadotropin-releasing hormone agonist with surgery

Men in whom hormone might be involved

THB

THB

leuprolide  acetate ,flutamide and degarelix, THB