Table 1. Detailed direct immunofluorescene findings in skin biopsies and ANA test results

Disorders (52)

Immunofluorescence pattern in skin biopsy

Immunoreactant positivity with ANA in vivo

Serum ANA results in 28 patients where ANA reports were available

 ANA  in vivo +LBT+ SBV

ANA in vivo +LBT

ANA in vivo+ SBV

ANA in vivo+

Civatte bodies

ANA in vivo only

IgG

IgA

IgM

C3

Speckled

Diffuse

Nucleolar

Mixed

Negative

SLE (20)

10

4

2

2

2

16

1

2

2

10

3

-

-

3

Vasculitis (13)

3

4

2

-

4

5

3

2

3

1

-

-

-

4

Systemic sclerosis (9)

-

6

-

-

3

7

1

1

-

-

-

1

2

-

DLE (3)

1

-

-

-

2

3

-

-

-

1

-

-

-

1

Sjogren’s syndrome (1)

1

-

-

-

-

1

-

-

-

-

-

-

-

-

Overlap syndrome (1)

-

-

-

-

1

1

-

-

-

1

-

-

-

-

Dermatomyositis (1)

-

-

1

-

-

1

-

-

-

-

-

1

-

-

Pemphigus vulgaris (2)*

-

-

-

-

2

-

-

2

-

-

-

-

-

-

Bullous pemhigoid (2)*

-

-

-

-

2

1

-

1

-

-

-

-

-

-

Total (52)

15

14

5

2

16

35

5

8

5

13

3

2

2

8

 

*In addition to ANF in vivo, PV patients showed intercellular positivity in the epidermis and BP patients showed linear positivity at the dermo-epidermal junction.

 

SLE-systemic lupus erythematosus; DLE-discoid lupus erythematosus; ANA-anti-nuclear antibody; LBT-lupus band test;SBV-superficial blood vessels