Table 3. Criteria for the diagnosis of leprosy
Type of leprosy |
Clinical criteria |
Histological criteria |
TT |
Well defined dry, atrophic scaly patch/plaque with near total/total loss of sensation |
Well formed epithelioid cell Granulomas distributed through out the dermis, encroaching/eroding the epidermis along with destruction of nerve and adnexal structures |
BT |
Well defined patch/plaque with moderate loss of sensation and presence of satellite lesions |
Well to ill defined granulomas having fewer number of lymphocytes and more giant cells and not encroaching upon the epidermis |
BB |
Multiple annular/geographic/bizarre shaped plaques with minimal loss of sensation |
Loosely arranged granuloma consisting epithelioid cells, few macrophages with scanty lymphocytes |
BL |
Multiple hypopigmented/coppery coloured small to medium sized patches or papules tending towards symmetry Asymmetrical nerve enlargement |
Ill defined granuloma rich in foamy histiocytes with admixture of few epithelioid cells |
LL |
Numerous hypopigmented/coppery coloured, shiny patches /papules /nodules with normal sensation Symmetric enlargement of nerves Infiltration of both ear lobes |
Diffuse macrophage granuloma consisting of foamy histiocytes with prominent Grenz zone and positive for AFB |
IL |
Ill to well defined hypopigmented non scaly patch with or without loss of sensation persisting for more than 6months |
Mild lymphocytic infiltration around nerve bundles, sweat glands and arrector pili muscle |