Patient

Age

Sex

Distribution of rash

Agent

Management

Outcome

Course of Illness

1

68

M

Generalised 

Dilantin

-Removal of agent

-IV hydrocortisone

Rash improved on day 5

Recovered on day 12

2

22

F

Face,lips,trunk with pustules

Unknown

-Removal of agent

-IV hydrocortisone, IVIG, Klacid

-Topical elomet lotion

Shortness of breath, required prophylactic intubation in ICU

Recovered on day 21

3

51

F

Face, limbs, perioral, perineum, sole and palm

Ciproxin,

NSAID

-Removal of agent

-IV hydrocortisone

Rash improved on day 5

Recovered on day 18

4

40

M

Perioral, Conjunctiva,Buccal mucosa

Acyclovir

-Removal of agent

-IV hydrocortisone,

-Topical Elomet, thymol gargle, Nadexin eye drop

Fever and rash started to improve on day 6

Recovered on day 16

5

32

F

Haemorrhagic spots over the face,lips, buccal mucosa and generalised MP rash. 

Acyclovir , Tegretol

-Removal of agent

-Oral prednisolone,

-Topical Daktacort, difflam mouthwash

Fever and rash improved on day 7

Recovered on day 17

6

46

F

Generalised MP rash and buccal mucosa haemorrhagic spots

Augmentin,Allopurinol

-Removal of agent

-IV hydrocortisone, Klacid

Fever and rash improved on day 4

Subsided on day 17

7

65

M

Truncal MP rash and mucosa ulcer

Cloxacillin, Ticlid

-Removal of agent

-IV hydrocortisone, Acyclovir

-Topical Synalar

 

Rash improved on day 3

Subsided on day 14

Table 1. Summary of details of patients treated at United Christian Hospital between 2001-2002. It may be noticed that the common causative agent is drug-induced. SJS commonly occurs in adults age>40. Male and female are equally affected. The rash usually starts improving on day 4-5 upon the routine treatment, i.e., IV corticosteroid. Most of our patients require more than 14 days to have their rash totally subsided.