Table 2. 9 Defining characteristics of Degos [2]
|
|
1. |
Histologically, Degos is a vasculopathy/endovasculitis |
2. |
Degos has two variants (a) Benign cutaneous (b) Systemic lethal |
3. |
An occlusive arteriopathy involves small-caliber vessels |
4. |
Tissue infarction occurs usually initially involving the skin |
5. |
Degos initially manifests w/ erythematous, pink/red papules |
6. |
Papules evolve into papules with porcelain atrophic centers |
7. |
In the systemic variant GI, brain & organ bleeding kills |
8. |
Immune, viral, and vascular/hematologic causes are posited |
9. |
Treatment has no effect on the course of Degos |