Table 12: Sugar content of available IVIg preperations in the U.S.

IVIg Trade Name

Indications

Sugar Content37

Flebogamma 5% DIF

Primary (inherited) humoral immunodeficiency disorders such as common variable immunodeficiency, x-linked agammaglobulinemia, severe combined immunodeficiency and Wiskott-Aldrich syndrome; used especially when rapid replacement of IgG or the attainment of high serum levels of IgG is desired 30

5% D-Sorbitol

Gammagard S/D

Primary immunodeficiency diseases (as above except selective IgA deficiency), B-cell Chronic Lymphocytic Leukemia, Idiopathic Thrombocytopenic Purpura (ITP), Kawasaki Syndrome (prevention of associated coronary artery aneurysms)31

2% Glucose

Gamunex

Primary humoral immunodeficiency (PI), Idiopathic Thrombocytopenic Purpura (ITP), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)32

No sugar added

Gammagard Liquid

Primary immunodeficiency33

No sugar added

Carimune NF

Primary immunodeficiency, ITP 34

1.67 gm/sucrose/gm

Privigen

Primary immunodeficiency, Chronic ITP35

No sugar added

Octagam

Primary immunodeficiency36

100 mg/ml maltose