Table 12: Sugar content of available IVIg preperations in the U.S.
IVIg Trade Name |
Indications |
Sugar Content37 |
Flebogamma 5% DIF |
Primary (inherited) humoral immunodeficiency disorders such as common variable immunodeficiency, x-linked agammaglobulinemia, severe combined immunodeficiency and Wiskott-Aldrich syndrome; used especially when rapid replacement of IgG or the attainment of high serum levels of IgG is desired 30 |
5% D-Sorbitol |
Gammagard S/D |
Primary immunodeficiency diseases (as above except selective IgA deficiency), B-cell Chronic Lymphocytic Leukemia, Idiopathic Thrombocytopenic Purpura (ITP), Kawasaki Syndrome (prevention of associated coronary artery aneurysms)31 |
2% Glucose |
Gamunex |
Primary humoral immunodeficiency (PI), Idiopathic Thrombocytopenic Purpura (ITP), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)32 |
No sugar added |
Gammagard Liquid |
Primary immunodeficiency33 |
No sugar added |
Carimune NF |
Primary immunodeficiency, ITP 34 |
1.67 gm/sucrose/gm |
Privigen |
Primary immunodeficiency, Chronic ITP35 |
No sugar added |
Octagam |
Primary immunodeficiency36 |
100 mg/ml maltose |