Table 2: DNA repair Adjuvants and Selected natural anti-oxidants:
CATEGORY |
ADJUVANT |
TRADE NAME |
ROUTE |
Mechanism |
Antioxidant |
DNA Repair |
Minerals |
Selenium, selenomethionine |
|
Oral |
Unclear ?NER |
Conflicting reports. |
? |
Carboxyl alkyl ester |
Uncaria tomentosa (aqueous extract) |
AC-11 (formerly C-MED-100) |
Topical, oral |
NER |
Yes |
Yes |
DNA repair enzyme |
T4 endonuclease V |
Dimericine |
Topical |
NER |
No |
Yes |
Heat shock protein |
Ubiquitin |
|
Experimental |
NER, Double strand breaks. |
No |
yes |
Cytokine |
Interleukin-12 |
|
Experimental |
NER |
No |
Yes |
Fern |
Polypodium leucotomos |
Heliocare |
Oral |
??Reduced UV induced damage to DNA repair mechanism |
Yes |
? |