Table 2: DNA repair Adjuvants and Selected natural anti-oxidants:

 

CATEGORY

ADJUVANT

TRADE NAME

ROUTE

Mechanism

Antioxidant

DNA Repair

Minerals

Selenium, selenomethionine

 

Oral

Unclear ?NER

Conflicting reports.

?

Carboxyl alkyl ester

Uncaria tomentosa

(aqueous extract)

AC-11 (formerly C-MED-100)

Topical, oral

NER

Yes

Yes

DNA repair enzyme

T4 endonuclease V

Dimericine

Topical

NER

No

Yes

Heat shock protein

Ubiquitin

 

Experimental

NER, Double strand breaks.

No

yes

Cytokine

Interleukin-12

 

Experimental

NER

No

Yes

Fern

Polypodium leucotomos

Heliocare

Oral

??Reduced UV induced damage to DNA repair mechanism

Yes

?