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    <title>Recent ics_inf_oapdeposits items</title>
    <link>https://escholarship.org/uc/ics_inf_oapdeposits/rss</link>
    <description>Recent eScholarship items from Open Access Policy Deposits</description>
    <pubDate>Sun, 21 Jun 2026 10:37:52 +0000</pubDate>
    <item>
      <title>We Need Granular Sharing of De-Identified Data—But Will Patients Engage? Investigating Health System Leaders' and Patients' Perspectives on A Patient-Controlled Data-Sharing Platform</title>
      <link>https://escholarship.org/uc/item/6hw6p6rb</link>
      <description>Patient-controlled data-sharing systems are increasingly promoted as a way to empower patients with greater autonomy over their health data. Yet it remains unclear how different stakeholders, especially patients and health system leaders, perceive the benefits and challenges of enabling granular control over the sharing of de-identified medical data for research. To address this gap, we developed a high-fidelity prototype of a patient-controlled, web-based consent platform and conducted a two-phase mixed-methods study: semi-structured interviews with 16 health system leaders and a survey with 523 patient participants. While both groups appreciated the potential of such a platform to enhance transparency and autonomy, their views diverged in meaningful ways. Leaders viewed transparency and granular control through the lens of informed consent and institutional ethics, whereas patients interpreted these factors as safeguards against potential risks and uncertainties. Our findings...</description>
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      <pubDate>Wed, 17 Jun 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Lu, Xi</name>
      </author>
      <author>
        <name>Hu, Di</name>
      </author>
      <author>
        <name>Nguyen, An T</name>
      </author>
      <author>
        <name>Morse, Brad</name>
      </author>
      <author>
        <name>Schilling, Lisa M</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
      <author>
        <name>Keller, Michelle S</name>
        <uri>https://orcid.org/0000-0002-8157-7586</uri>
      </author>
      <author>
        <name>Ohno-Machado, Lucila</name>
      </author>
      <author>
        <name>Chen, Yunan</name>
      </author>
    </item>
    <item>
      <title>Correction: The social amplification and attenuation of COVID-19 risk perception shaping mask wearing behavior: A longitudinal twitter analysis</title>
      <link>https://escholarship.org/uc/item/03z98750</link>
      <description>[This corrects the article DOI: 10.1371/journal.pone.0257428.].</description>
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      <pubDate>Wed, 17 Jun 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Hopfer, Suellen</name>
        <uri>https://orcid.org/0000-0003-3232-9743</uri>
      </author>
      <author>
        <name>Fields, Emilia J</name>
      </author>
      <author>
        <name>Lu, Yuwen</name>
      </author>
      <author>
        <name>Ramakrishnan, Ganesh</name>
      </author>
      <author>
        <name>Grover, Ted</name>
      </author>
      <author>
        <name>Bai, Qiushi</name>
      </author>
      <author>
        <name>Huang, Yicong</name>
      </author>
      <author>
        <name>Li, Chen</name>
      </author>
      <author>
        <name>Mark, Gloria</name>
      </author>
    </item>
    <item>
      <title>Shaping HCI Research for Children's Care Ecosystem Involvement</title>
      <link>https://escholarship.org/uc/item/45x6w8q7</link>
      <description>Recent HCI research emphasizes the importance of considering children’s care ecosystems in the design of technologies, extending the focus beyond families to include teachers, peers, therapists, and institutions. While this ecosystem perspective opens opportunities for more inclusive and collaborative technologies, it also introduces challenges such as recruitment, power dynamics, reconciling diverse perspectives, and complex ethical considerations. This CHI 2026 workshop builds on prior community efforts at IDC 2023, CHI 2024, and IDC 2025. Its primary focus is on children’s care ecosystems, but we also welcome researchers working with other populations who wish to apply an ecosystem lens. The workshop will bring together researchers and practitioners to discuss opportunities, challenges, and methods, and to collaboratively articulate a research agenda for care ecosystem-centered HCI. Participants will engage in mapping and synthesis activities that produce care ecosystem maps...</description>
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      <pubDate>Wed, 6 May 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Stefanidi, Evropi</name>
      </author>
      <author>
        <name>Silva, Lucas M</name>
      </author>
      <author>
        <name>Cagiltay, Bengisu</name>
      </author>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Eriksson, Eva</name>
      </author>
      <author>
        <name>Hayes, Gillian R</name>
      </author>
    </item>
    <item>
      <title>FamilyBloom: Examining Ecologies of Collaboration in Family-Centered Health Tracking</title>
      <link>https://escholarship.org/uc/item/2hs1f70b</link>
      <description>Family health informatics tools can help support well-being with shared data tracking. Prior work typically focused on shared data review, but often in specific moments, like bedtime, or centered on caregiving of children or elderly members. To investigate how tracking can support mutual health collaboration between family members pervasively across daily contexts, we designed and deployed FamilyBloom, a glanceable smartwatch and home display system for mood and goal tracking. Twelve families with both neurotypical and ADHD members used FamilyBloom for three months on average. Our findings reveal how family-centered tracking created collaboration opportunities and tensions across multiple ecological systems: individual self-regulation, collaborations within family dynamics, involvement of care networks with varying trust levels, institutional school constraints and cultural stigma, and temporality of regular routines and crisis periods. We discuss an ecosystem-aware approach to...</description>
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      <pubDate>Wed, 6 May 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Silva, Lucas M</name>
      </author>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Stefanidi, Evropi</name>
      </author>
      <author>
        <name>Cibrian, Franceli L</name>
      </author>
      <author>
        <name>Beltran, Jesus A</name>
      </author>
      <author>
        <name>Zeiler, Cassie</name>
      </author>
      <author>
        <name>Schuck, Sabrina</name>
      </author>
      <author>
        <name>Lakes, Kimberley D</name>
      </author>
      <author>
        <name>Hayes, Gillian R</name>
      </author>
      <author>
        <name>Epstein, Daniel A</name>
        <uri>https://orcid.org/0000-0002-2657-6345</uri>
      </author>
    </item>
    <item>
      <title>Collaboration and Assistive Technology: Facilitating Joint Awareness for Noise Sensitivity</title>
      <link>https://escholarship.org/uc/item/2cr472z8</link>
      <description>Existing research has explored various methods to support people with noise sensitivity (PWNS), from desensitization therapies to technological solutions. However, there is a gap in systems that identify and monitor characteristics of noise sensitivity experiences to help PWNS and their companions better understand their condition and make informed management decisions. To fill this gap, we developed AudioBuddy, an app with sensing and tracking features designed to promote awareness between PWNS and their companions. We tested AudioBuddy as a technological probe over a two-week field deployment. Our results show that AudioBuddy can support awareness of how sounds and environments influence the psychophysiological states of PWNS, aiding in understanding noise sensitivity experiences. Nonetheless, technical limitations impacted the depth of awareness participants could attain. We discuss challenges and opportunities for future systems to facilitate awareness among PWNS and their...</description>
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      <pubDate>Wed, 6 May 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Hicks, Emani</name>
      </author>
      <author>
        <name>Rieffel, Luc</name>
      </author>
      <author>
        <name>Gowda, Ariya</name>
      </author>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Hayes, Gillian R</name>
      </author>
    </item>
    <item>
      <title>Understanding the Perspectives of Autistic Gamers through an Online Autistic Community and a Survey</title>
      <link>https://escholarship.org/uc/item/2qr8z5d0</link>
      <description>Autistic people often have an interest in and spend a substantial amount of time engaged with video games. Games can be supportive of their mental health and social needs and have been widely used for behavioral interventions among autistic people. However, the gaming experiences and preferences of autistic people themselves have not been thoroughly studied. To explore these experiences, we used a multi-method approach, analyzing game-related posts from a large autism-related subreddit and conducting a survey with 145 autistic people. The survey allowed us to further understand preferences around accessibility and sensory experiences, representation, and social experiences in communities that emerged in the Reddit posts. We found that games offering a sense of freedom, control, and creativity might be particularly appealing to autistic gamers. Discussions also emerged around what types of audio and visual sensory input were considered soothing and appropriate. Moreover, both the...</description>
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      <pubDate>Wed, 22 Apr 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Park, Sohyeon</name>
      </author>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Piper, Anne Marie</name>
      </author>
      <author>
        <name>Hayes, Gillian R</name>
      </author>
    </item>
    <item>
      <title>DermaVision</title>
      <link>https://escholarship.org/uc/item/8mz35921</link>
      <description>Approximately 10 million people in the United States suffer from domestic violence annually, with 4 out of 10 cases affecting people of color. Traditional coloration guides remain the primary forensic strategy to evaluate bruise injuries, which are highly subjective and inaccurate for monitoring bruises. Additionally, this approach fails to consider bruise pigmentation in darker skin tones, and the results of this qualitative method vary by the medical professional conducting the inspection. There is a need for reliable, quantitative bruise information across all skin tones that can be utilized in both medicine and justice. DermaVision aims to address this need by designing a portable multi-spectral camera to quantitatively analyze bruises in diverse skin tones. By correlating the reflective spectra of a bruise with its age and healing progression, our camera will provide an accurate timeline for when bruises occur irrespective of patients’ skin color. This technology will assist...</description>
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      <pubDate>Wed, 15 Apr 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Frazeur, Mitchell</name>
      </author>
      <author>
        <name>Reyes, Alejandra</name>
      </author>
      <author>
        <name>Im, Ashley</name>
      </author>
      <author>
        <name>Ngo, Hao</name>
      </author>
      <author>
        <name>Ly, Christine</name>
      </author>
      <author>
        <name>Lo, Matthew</name>
      </author>
      <author>
        <name>Lee, Gerald</name>
      </author>
      <author>
        <name>Jimenez, Siana</name>
      </author>
      <author>
        <name>Nutz, Derek</name>
      </author>
      <author>
        <name>Chei, Joseph</name>
      </author>
      <author>
        <name>Arias, Jazmin</name>
      </author>
      <author>
        <name>Lam, Jessica</name>
      </author>
    </item>
    <item>
      <title>The effectiveness of participatory near-peer digital media literacy interventions</title>
      <link>https://escholarship.org/uc/item/0xm1f4mk</link>
      <description>The impacts of digital media literacy (DML) interventions are mixed, perhaps due to adult-driven curricula and misalignment with youth’s needs. We tested how student-led, developmentally-informed DML education could leverage youth’s expertise. Using Youth Participatory Action Research and near-peer mentoring, high school students (n = 31) designed and taught digital literacy interventions in two areas (1) digital communication (i.e. group-chats) and (2) persuasive design (e.g. features such as infinite scroll), resulting in significant increases in knowledge of digital communication conflict prevention and remediation strategies, along with identification and knowledge of persuasive design for 79 middle and 31 high school students. High schoolers also reported more feelings of agency and research knowledge. These findings indicate that making DML interventions developmentally aligned might be key for supporting youth in the digital age.</description>
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      <pubDate>Wed, 15 Apr 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Dingle, Kyra</name>
      </author>
      <author>
        <name>Reich, Stephanie M</name>
        <uri>https://orcid.org/0000-0002-8799-5236</uri>
      </author>
      <author>
        <name>Starks, Allison</name>
      </author>
      <author>
        <name>Harel-Marian, Taly</name>
      </author>
    </item>
    <item>
      <title>Video Games and Learning</title>
      <link>https://escholarship.org/uc/item/9nt4d05x</link>
      <description>The interdisciplinary field of the learning sciences encompasses educational psychology, cognitive science, computer science, and anthropology, among other disciplines. The Cambridge Handbook of the Learning Sciences, first published in 2006, is the definitive introduction to this innovative approach to teaching, learning, and educational technology. In this significantly revised third edition, leading scholars incorporate the latest research to provide seminal overviews of the field. This research is essential in developing effective innovations that enhance student learning - including how to write textbooks, design educational software, prepare effective teachers, and organize classrooms. The chapters illustrate the importance of creating productive learning environments both inside and outside school, including after school clubs, libraries, and museums. The Handbook has proven to be an essential resource for graduate students, researchers, consultants, software designers,...</description>
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      <pubDate>Mon, 30 Mar 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Steinkuehler, Constance</name>
      </author>
      <author>
        <name>Squire, Kurt</name>
      </author>
    </item>
    <item>
      <title>Situating Big Data</title>
      <link>https://escholarship.org/uc/item/5vq5065q</link>
      <description>Lacking a digital crystal ball, we cannot predict the future of education or the precise instructional role games will have going forward. Yet we can safely say that games will play some role in the future of K-12 and higher education, and members of the games community will have to choose between being passive observers or active, progressive contributors to the complex and often political process of weaving together pedagogy, technology, and culture. This will involve agreeing that games—or, more specifically, game mechanics and the engagement in joyful learning that they engender—are not only critical for shaping online and classroom instruction but also the evolution of schooling as a whole. Likewise, it will involve a hard push beyond questions like “Are video games ‘good’ or ‘bad’ for education?” and “Are games ‘better’ for all students than traditional face-to-face teaching” to unpack how game experiences vary with individual learner goals as an interaction with the parameters...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5vq5065q</guid>
      <pubDate>Mon, 30 Mar 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Dalsen, Jennifer</name>
      </author>
      <author>
        <name>Anderson, Craig G</name>
      </author>
      <author>
        <name>Squire, Kurt</name>
      </author>
      <author>
        <name>Steinkuehler, Constance</name>
      </author>
    </item>
    <item>
      <title>Editorial: Extremism in games</title>
      <link>https://escholarship.org/uc/item/4g39t0p1</link>
      <description>Editorial: Extremism in games</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4g39t0p1</guid>
      <pubDate>Mon, 30 Mar 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Kowert, Rachel</name>
      </author>
      <author>
        <name>Lakhani, Suraj</name>
      </author>
      <author>
        <name>Steinkuehler, Constance</name>
      </author>
    </item>
    <item>
      <title>PIKACHU: (est. 1996) Franchise: Pokémon Developer: Game Freak</title>
      <link>https://escholarship.org/uc/item/44h8b3nv</link>
      <description>PIKACHU: (est. 1996) Franchise: Pokémon Developer: Game Freak</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/44h8b3nv</guid>
      <pubDate>Mon, 30 Mar 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Saucerman, J</name>
      </author>
      <author>
        <name>Steinkuehler, C</name>
      </author>
    </item>
    <item>
      <title>When AI Writes Back: Ethical Considerations by Physicians on AI-Drafted Patient Message Replies.</title>
      <link>https://escholarship.org/uc/item/9fb33523</link>
      <description>The increasing burden of responding to large volumes of patient messages has become a key factor contributing to physician burnout. Generative AI (GenAI) shows great promise to alleviate this burden by automatically drafting patient message replies. The ethical implications of this use have however not been fully explored. To address this knowledge gap, we conducted a qualitative interview study with 21 physicians who participated in a GenAI pilot program. We found that notable ethical considerations expressed by the physician participants included oversight as ethical safeguard, transparency and patient consent of AI use, patient misunderstanding of AI's role, and patient privacy and data security as prerequisites. Additionally, our findings suggest that the physicians believe the ethical responsibility of using GenAI in this context primarily lies with users, not with the technology. These findings may provide useful insights into guiding the future implementation of GenAI in...</description>
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      <pubDate>Wed, 11 Mar 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Hu, Di</name>
      </author>
      <author>
        <name>Guo, Yawen</name>
      </author>
      <author>
        <name>Cho, Ha Na</name>
      </author>
      <author>
        <name>Chow, Emilie</name>
      </author>
      <author>
        <name>Mukamel, Dana B</name>
        <uri>https://orcid.org/0000-0003-4147-5785</uri>
      </author>
      <author>
        <name>Sorkin, Dara</name>
        <uri>https://orcid.org/0000-0003-0742-9240</uri>
      </author>
      <author>
        <name>Reikes, Andrew</name>
      </author>
      <author>
        <name>Perret, Danielle</name>
      </author>
      <author>
        <name>Pandita, Deepti</name>
        <uri>https://orcid.org/0009-0007-2791-2738</uri>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
    </item>
    <item>
      <title>Perceptions of AI-Driven EdTech: Nationwide Survey and Focus Group Insights from Key End Users</title>
      <link>https://escholarship.org/uc/item/676617cd</link>
      <description>Schoolchildren in the United States are increasingly exposed to educational technologies (EdTech), many of which are or will be infused with Artificial Intelligence (AI). Despite this growing integration, there is limited understanding of the current perceptions and attitudes toward EdTech with AI among parents, teachers, and teens. To address this gap, we conducted a mixed-method study involving an A/B experiment through an online survey with 3,051 participants and complemented by focus group discussions with 80 participants. Providing a comprehensive snapshot of AI perception in education in 2024, our findings indicate that participants, particularly teachers, may hold more negative perceptions of our AI-powered EdTech mock-up compared to the one powered by human tutors. Based on these insights, we discuss the future of EdTech regarding the current perceptions. This research contributes to an empirical understanding of the perceptions and attitudes toward AI in K-12 education,...</description>
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      <pubDate>Wed, 11 Mar 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Dickerson, Kelli</name>
      </author>
      <author>
        <name>Park, Sohyeon</name>
      </author>
      <author>
        <name>Hicks, Emani</name>
      </author>
      <author>
        <name>Han, Ariel</name>
      </author>
      <author>
        <name>Rubin, Jennifer D</name>
      </author>
      <author>
        <name>Lombard, Ella</name>
      </author>
      <author>
        <name>Chen, Katharine</name>
      </author>
      <author>
        <name>Divanji, Riddhi</name>
      </author>
      <author>
        <name>Odgers, Candice</name>
        <uri>https://orcid.org/0000-0003-4937-6618</uri>
      </author>
      <author>
        <name>Hayes, Gillian R</name>
      </author>
    </item>
    <item>
      <title>What Remotely Matters? Understanding Individual, Team, and Organizational Factors in Remote Work at Scale</title>
      <link>https://escholarship.org/uc/item/8sd2q0tt</link>
      <description>Although knowledge workers are increasingly able to adopt remote and hybrid working arrangements and work productively, many organizations continue to question the effectiveness of remote work and focus on its concerns and challenges. Previous CSCW research shows that remote workers have limited awareness of other workers, require more explicit coordination, and feel excluded from in-person colleagues. Research also shows that adopting work practices and technologies that are remote work-friendly can offset many of these challenges. Identifying which effective practices and challenges are most helpful or hurtful to remote workers-and how workplace attributes (e.g., team structure; communication frequency; tool use) affect them-could strengthen organizations' strategies and policies for remote work. Through a theoretically-informed survey of 1,526 U.S. knowledge workers, we find many factors prior research has argued as essential to remote work, such as knowing your teammates personally,...</description>
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      <pubDate>Thu, 15 Jan 2026 00:00:00 +0000</pubDate>
      <author>
        <name>Garg, Kapil</name>
      </author>
      <author>
        <name>Gómez-Zará, Diego</name>
      </author>
      <author>
        <name>Gerber, Elizabeth</name>
      </author>
      <author>
        <name>Gergle, Darren</name>
      </author>
      <author>
        <name>Contractor, Noshir</name>
      </author>
      <author>
        <name>Massimi, Michael</name>
      </author>
    </item>
    <item>
      <title>Understanding How Personal Activities Are Shared In Short-form Videos</title>
      <link>https://escholarship.org/uc/item/5bp9q190</link>
      <description>Sharing activities that people do in everyday life, such as physical activity, health management, or hobbies, help people receive benefits like social support and positive self-presentation. Short-form videos present new opportunities for activity-sharing, which has traditionally been studied in static contexts like text- and image-sharing. We therefore aim to understand what information people incorporate into short-form activity videos, and how. We qualitatively analyzed 420 short-form activity videos on TikTok across three domains: running, studying, and sketching. We found people often present information before, during, and after activities, developing strategies for qualitatively and quantitatively incorporating activity-relevant information in each. We also uncover practices for aligning the sharing of activity-relevant information with the nature of short-form videos, such as modifying broader-scale goals into video-scale goals. We further discuss design opportunities...</description>
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      <pubDate>Wed, 22 Oct 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Wang, Dennis</name>
      </author>
      <author>
        <name>Zhu, Jun</name>
      </author>
      <author>
        <name>Epstein, Daniel A</name>
        <uri>https://orcid.org/0000-0002-2657-6345</uri>
      </author>
    </item>
    <item>
      <title>Understanding Mental Wellbeing and Tools for Support with Taiwanese Emerging Adults: An Eastern Cultural Perspective</title>
      <link>https://escholarship.org/uc/item/65s7b1bp</link>
      <description>Understanding Mental Wellbeing and Tools for Support with Taiwanese Emerging Adults: An Eastern Cultural Perspective</description>
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      <pubDate>Thu, 25 Sep 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Cheng, Nai-Yu</name>
      </author>
      <author>
        <name>Wong, Novia</name>
      </author>
      <author>
        <name>Reddy, Madhu</name>
      </author>
    </item>
    <item>
      <title>'It's a spectrum': Exploring Autonomy, Competence, and Relatedness in Software Development Processes and Tools</title>
      <link>https://escholarship.org/uc/item/33n3t4dg</link>
      <description>The recent surge of research on software developer mental health challenges highlights the importance and urgency of studying solutions to support developer wellbeing. Self-Determination Theory (SDT) offers a valuable framework for exploring wellbeing at work, emphasizing the need to satisfy three psychological needs: autonomy, competence, and relatedness. This paper presents an interview study with 31 software developers in the United States that uses SDT as a guide, exploring how these three needs are perceived and influenced in the work of software developers. We identify specific factors and processes at work and work tools and designs that impact developers' psychological needs and satisfaction. Results from our study can help design targeted solutions to satisfy developers psychological needs, which indirectly support developer wellbeing. This paper highlights the necessity of healthy work cultures in software development and presents design considerations for creating tools...</description>
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      <pubDate>Thu, 25 Sep 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Wong, Novia</name>
      </author>
      <author>
        <name>Cheng, Nai-Yu</name>
      </author>
      <author>
        <name>Oewel, Bruna</name>
      </author>
      <author>
        <name>Genuario, Katherine E</name>
      </author>
      <author>
        <name>Stoeckl, SarahElizabeth</name>
      </author>
      <author>
        <name>Schueller, Stephen M</name>
        <uri>https://orcid.org/0000-0002-1003-0399</uri>
      </author>
      <author>
        <name>Ahmed, Iftekhar</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
      <author>
        <name>Reddy, Madhu</name>
      </author>
    </item>
    <item>
      <title>Approaches for tailoring between-session mental health therapy activities</title>
      <link>https://escholarship.org/uc/item/90s340r4</link>
      <description>Mental health activities conducted by patients between therapy sessions (or "therapy homework") are a component of addressing anxiety and depression. However, to be effective, therapy homework must be tailored to the client's needs to address the numerous barriers they encounter in everyday life. In this study, we analyze how therapists and clients tailor therapy homework to their client's needs. We interviewed 13 therapists and 14 clients about their experiences tailoring and engaging in therapy homework. We identify criteria for tailoring homework, such as client skills, discomfort, and external barriers. We present how homework gets adapted, such as through changes in difficulty or by identifying alternatives. We discuss how technologies can better use client information for personalizing mental health interventions, such as adapting to client barriers, adjusting homework to these barriers, and creating a safer environment to support discomfort.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/90s340r4</guid>
      <pubDate>Wed, 30 Jul 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Oewel, Bruna</name>
      </author>
      <author>
        <name>Arean, Patricia Anne</name>
      </author>
      <author>
        <name>Agapie, Elena</name>
      </author>
    </item>
    <item>
      <title>Preparing and Experiencing Food During Life Events: Implications for Technology Supporting Social and Value Changes</title>
      <link>https://escholarship.org/uc/item/3z32c080</link>
      <description>Preparing and Experiencing Food During Life Events: Implications for Technology Supporting Social and Value Changes</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3z32c080</guid>
      <pubDate>Wed, 30 Jul 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Ha, Seung Wan</name>
      </author>
      <author>
        <name>Nurain, Novia</name>
      </author>
      <author>
        <name>Agapie, Elena</name>
      </author>
      <author>
        <name>Chung, Chia-Fang</name>
        <uri>https://orcid.org/0000-0002-3374-2073</uri>
      </author>
    </item>
    <item>
      <title>Conducting Research at the Intersection of HCI and Health: Building and Supporting Teams with Diverse Expertise to Increase Public Health Impact</title>
      <link>https://escholarship.org/uc/item/0322m8bf</link>
      <description>Research at the intersection of human-computer interaction (HCI) and health is increasingly done by collaborative cross-disciplinary teams. The need for cross-disciplinary teams arises from the interdisciplinary nature of the work itself-with the need for expertise in a health discipline, experimental design, statistics, and computer science, in addition to HCI. This work can also increase innovation, transfer of knowledge across fields, and have a higher impact on communities. To succeed at a collaborative project, researchers must effectively form and maintain a team that has the right expertise, integrate research perspectives and work practices, align individual and team goals, and secure funding to support the research. However, successfully operating as a team has been challenging for HCI researchers, and can be limited due to a lack of training, shared vocabularies, lack of institutional incentives, support from funding agencies, and more; which significantly inhibits their...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0322m8bf</guid>
      <pubDate>Wed, 30 Jul 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Agapie, Elena</name>
      </author>
      <author>
        <name>Karkar, Ravi</name>
      </author>
      <author>
        <name>Aung, Tricia</name>
      </author>
      <author>
        <name>Burgess, Eleanor R</name>
      </author>
      <author>
        <name>Chinguwa, Munyaradzi Joel</name>
      </author>
      <author>
        <name>Graham, Andrea K</name>
      </author>
      <author>
        <name>Klasnja, Predrag</name>
      </author>
      <author>
        <name>Lyon, Aaron</name>
      </author>
      <author>
        <name>McCall, Terika</name>
      </author>
      <author>
        <name>Munson, Sean A</name>
      </author>
      <author>
        <name>Nunes, Francisco</name>
      </author>
      <author>
        <name>Osterhage, Katie</name>
      </author>
    </item>
    <item>
      <title>Transfer Learning in Animal Facial Expression Recognition: A Comparative Study Using Human Pre-Trained Models</title>
      <link>https://escholarship.org/uc/item/86x8v0m3</link>
      <description>Transfer Learning in Animal Facial Expression Recognition: A Comparative Study Using Human Pre-Trained Models</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/86x8v0m3</guid>
      <pubDate>Mon, 21 Jul 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Wang, Emily G</name>
        <uri>https://orcid.org/0009-0003-8941-3177</uri>
      </author>
    </item>
    <item>
      <title>Creative Problem-Solving: A Study With Blind and Low Vision Software Professionals</title>
      <link>https://escholarship.org/uc/item/4ps2r51w</link>
      <description>Background: Software engineering requires both technical skills and creative problem-solving. Blind and low-vision software professionals (BLVSPs) encounter numerous workplace challenges, including inaccessible tools and collaboration hurdles with sighted colleagues. Objective: This study explores the innovative strategies employed by BLVSPs to overcome these accessibility barriers, focusing on their custom solutions and the importance of supportive communities. Methodology: We conducted semi-structured interviews with 30 BLVSPs and used refexive thematic analysis to identify key themes. Results: Findings reveal that BLVSPs are motivated to develop creative and adaptive solutions, highlighting the vital role of collaborative communities in fostering shared problem-solving. Conclusion: For BLVSPs, creative problem-solving is essential for navigating inaccessible work environments, in contrast to sighted peers, who pursue optimization. This study enhances understanding of how BLVSPs...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4ps2r51w</guid>
      <pubDate>Wed, 16 Jul 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Kohl, Karina</name>
      </author>
      <author>
        <name>Cha, Yoonha</name>
      </author>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>Branham, Stacy</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
      </author>
    </item>
    <item>
      <title>Investigating the effects of housing instability on depression, anxiety, and mental health treatment in childhood and adolescence.</title>
      <link>https://escholarship.org/uc/item/642261f6</link>
      <description>Housing instability is a widespread phenomenon in the United States. In combination with other social determinants of health, housing instability affects children's overall health and development. Drawing on data from the 2022 National Survey of Children's Health, we employed multiple logistic regression models to understand how sociodemographic factors, especially housing instability, affect mental health outcomes and treatment access for youth aged 6-17 years. Our results show that youth facing housing instability have a higher likelihood of experiencing anxiety (OR: 1.42, p&amp;lt;0.001) and depression (OR: 1.57, p&amp;lt;0.001). Furthermore, youth experiencing both mental health conditions and housing instability are significantly less likely to receive mental health services in the past year, indicating the substantial barriers they face in accessing mental health care. Based on our findings, we highlight opportunities for digital mental health interventions to provide children experiencing...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/642261f6</guid>
      <pubDate>Fri, 6 Jun 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Zehrung, Rachael</name>
      </author>
      <author>
        <name>Hu, Di</name>
      </author>
      <author>
        <name>Guo, Yawen</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
      <author>
        <name>Chen, Yunan</name>
      </author>
    </item>
    <item>
      <title>Using Large Language Models for sentiment analysis of health-related social media data: empirical evaluation and practical tips.</title>
      <link>https://escholarship.org/uc/item/0nt052sm</link>
      <description>Health-related social media data generated by patients and the public provide valuable insights into patient experiences and opinions toward health issues such as vaccination and medical treatments. Using Natural Language Processing (NLP) methods to analyze such data, however, often requires high-quality annotations that are difficult to obtain. The recent emergence of Large Language Models (LLMs) such as the Generative Pre-trained Transformers (GPTs) has shown promising performance on a variety of NLP tasks in the health domain with little to no annotated data. However, their potential in analyzing health-related social media data remains underexplored. In this paper, we report empirical evaluations of LLMs (GPT-3.5-Turbo, FLAN-T5, and BERT-based models) on a common NLP task of health-related social media data: sentiment analysis for identifying opinions toward health issues. We explored how different prompting and fine-tuning strategies affect the performance of LLMs on social...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0nt052sm</guid>
      <pubDate>Fri, 6 Jun 2025 00:00:00 +0000</pubDate>
      <author>
        <name>He, Lu</name>
      </author>
      <author>
        <name>Omranian, Samaneh</name>
      </author>
      <author>
        <name>McRoy, Susan</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
    </item>
    <item>
      <title>Comparing the quality of human and ChatGPT feedback of students’ writing</title>
      <link>https://escholarship.org/uc/item/6k61v37f</link>
      <description>Background: Offering students formative feedback on their writing is an effective way to facilitate writing development. Recent advances in AI (i.e., ChatGPT) may function as an automated writing evaluation tool, increasing the amount of feedback students receive and diminishing the burden on teachers to provide frequent feedback to large classes. Aims: We examined the ability of generative AI (ChatGPT) to provide formative feedback. We compared the quality of human and AI feedback by scoring the feedback each provided on secondary student essays. We scored the degree to which feedback (a) was criteria-based, (b) provided clear directions for improvement, (c) was accurate, (d) prioritized essential features, and (e) used a supportive tone. Sample: 200 pieces of human-generated formative feedback and 200 pieces of AI-generated formative feedback for the same essays. Methods: We examined whether ChatGPT and human feedback differed in quality for the whole sample, for compositions...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6k61v37f</guid>
      <pubDate>Wed, 21 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Steiss, Jacob</name>
      </author>
      <author>
        <name>Tate, Tamara</name>
        <uri>https://orcid.org/0000-0002-1753-8435</uri>
      </author>
      <author>
        <name>Graham, Steve</name>
      </author>
      <author>
        <name>Cruz, Jazmin</name>
      </author>
      <author>
        <name>Hebert, Michael</name>
      </author>
      <author>
        <name>Wang, Jiali</name>
      </author>
      <author>
        <name>Moon, Youngsun</name>
      </author>
      <author>
        <name>Tseng, Waverly</name>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
      <author>
        <name>Olson, Carol Booth</name>
      </author>
    </item>
    <item>
      <title>Incorporating generative AI into a writing-intensive undergraduate course without off-loading learning</title>
      <link>https://escholarship.org/uc/item/5v18d712</link>
      <description>As generative AI becomes ubiquitous, writers must decide if, when, and how to incorporate generative AI into their writing process. Educators must sort through their role in preparing students to make these decisions in a quickly evolving technological landscape. We created an AI-enabled writing tool that provides scaffolded use of a large language model as part of a research study on integrating generative AI into an upper division STEM writing-intensive course. Drawing on decades of research on integrating digital tools into instruction and writing research, we discuss the framework that drove our initial design considerations and instructional resources. We then share our findings from a year of design-based implementation research during the 2023–2024 academic year. Our original instruction framework identified the need for students to understand, access, prompt, corroborate, and incorporate the generative AI use effectively. In this paper, we explain the need for students...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5v18d712</guid>
      <pubDate>Wed, 21 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Tate, Tamara P</name>
        <uri>https://orcid.org/0000-0002-1753-8435</uri>
      </author>
      <author>
        <name>Harnick-Shapiro, Beth</name>
      </author>
      <author>
        <name>Ritchie, Daniel Robert</name>
      </author>
      <author>
        <name>Tseng, Waverly</name>
      </author>
      <author>
        <name>Dennin, Michael</name>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
    </item>
    <item>
      <title>The affordances and contradictions of AI-generated text for writers of english as a second or foreign language</title>
      <link>https://escholarship.org/uc/item/4v65m5p8</link>
      <description>The affordances and contradictions of AI-generated text for writers of english as a second or foreign language</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4v65m5p8</guid>
      <pubDate>Wed, 21 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
      <author>
        <name>Tseng, Waverly</name>
      </author>
      <author>
        <name>Yim, Soobin</name>
      </author>
      <author>
        <name>Webster, Thomas</name>
      </author>
      <author>
        <name>Jacob, Sharin</name>
      </author>
      <author>
        <name>Du, Qian</name>
        <uri>https://orcid.org/0000-0002-9437-6935</uri>
      </author>
      <author>
        <name>Tate, Tamara</name>
        <uri>https://orcid.org/0000-0002-1753-8435</uri>
      </author>
    </item>
    <item>
      <title>Mind reading?</title>
      <link>https://escholarship.org/uc/item/3c35m9p0</link>
      <description>Mind reading?</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3c35m9p0</guid>
      <pubDate>Wed, 21 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Krapp, Peter</name>
        <uri>https://orcid.org/0000-0002-2854-5403</uri>
      </author>
    </item>
    <item>
      <title>“ChatGPT seems too good to be true”: College students’ use and perceptions of generative AI</title>
      <link>https://escholarship.org/uc/item/2gf4p9hh</link>
      <description>This study investigates how U.S. college students (N = 1001) perceive and use ChatGPT, exploring its relationship with societal structures and student characteristics. Regression results show that gender, age, major, institution type, and institutional policy significantly influenced ChatGPT use for general, writing, and programming tasks. Students in their 30s–40s were more likely to use ChatGPT frequently than younger students. Non-native English speakers were more likely than native speakers to use ChatGPT frequently for writing, suggesting its potential as a support tool for language learners. Institutional policies allowing ChatGPT use predicted higher use of ChatGPT. Thematic analysis and natural language processing of open-ended responses revealed varied attitudes towards ChatGPT, with some fearing institutional punishment for using ChatGPT and others confident in their appropriate use of ChatGPT. Computer science majors expressed concerns about job displacement due to...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2gf4p9hh</guid>
      <pubDate>Wed, 21 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Baek, Clare</name>
      </author>
      <author>
        <name>Tate, Tamara</name>
        <uri>https://orcid.org/0000-0002-1753-8435</uri>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
    </item>
    <item>
      <title>Can AI provide useful holistic essay scoring?</title>
      <link>https://escholarship.org/uc/item/1p34x8d9</link>
      <description>Researchers have sought for decades to automate holistic essay scoring. Over the years, these programs have improved significantly. However, accuracy requires significant amounts of training on human-scored texts—reducing the expediency and usefulness of such programs for routine uses by teachers across the nation on non-standardized prompts. This study analyzes the output of multiple versions of ChatGPT scoring of secondary student essays from three extant corpora and compares it to quality human ratings. We find that the current iteration of ChatGPT scoring is not statistically significantly different from human scoring; substantial agreement with humans is achievable and may be sufficient for low-stakes, formative assessment purposes. However, as large language models evolve additional research will be needed to continue to assess their aptitude for this task as well as determine whether their proximity to human scoring can be improved through prompting or training.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1p34x8d9</guid>
      <pubDate>Wed, 21 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Tate, Tamara P</name>
        <uri>https://orcid.org/0000-0002-1753-8435</uri>
      </author>
      <author>
        <name>Steiss, Jacob</name>
      </author>
      <author>
        <name>Bailey, Drew</name>
      </author>
      <author>
        <name>Graham, Steve</name>
      </author>
      <author>
        <name>Moon, Youngsun</name>
      </author>
      <author>
        <name>Ritchie, Daniel</name>
      </author>
      <author>
        <name>Tseng, Waverly</name>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
    </item>
    <item>
      <title>myAURA: a personalized health library for epilepsy management via knowledge graph sparsification and visualization</title>
      <link>https://escholarship.org/uc/item/8rc6m56k</link>
      <description>OBJECTIVES: Report the development of the patient-centered myAURA application and suite of methods designed to aid epilepsy patients, caregivers, and clinicians in making decisions about self-management and care.
MATERIALS AND METHODS: myAURA rests on an unprecedented collection of epilepsy-relevant heterogeneous data resources, such as biomedical databases, social media, and electronic health records (EHRs). We use a patient-centered biomedical dictionary to link the collected data in a multilayer knowledge graph (KG) computed with a generalizable, open-source methodology.
RESULTS: Our approach is based on a novel network sparsification method that uses the metric backbone of weighted graphs to discover important edges for inference, recommendation, and visualization. We demonstrate by studying drug-drug interaction from EHRs, extracting epilepsy-focused digital cohorts from social media, and generating a multilayer KG visualization. We also present our patient-centered design...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8rc6m56k</guid>
      <pubDate>Thu, 8 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Correia, Rion Brattig</name>
      </author>
      <author>
        <name>Rozum, Jordan C</name>
      </author>
      <author>
        <name>Cross, Leonard</name>
      </author>
      <author>
        <name>Felag, Jack</name>
      </author>
      <author>
        <name>Gallant, Michael</name>
      </author>
      <author>
        <name>Guo, Ziqi</name>
      </author>
      <author>
        <name>Herr, Bruce W</name>
      </author>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Sanchez-Valle, Jon</name>
      </author>
      <author>
        <name>Rocha, Deborah Stungis</name>
      </author>
      <author>
        <name>Valencia, Alfonso</name>
      </author>
      <author>
        <name>Wang, Xuan</name>
      </author>
      <author>
        <name>Börner, Katy</name>
      </author>
      <author>
        <name>Miller, Wendy</name>
      </author>
      <author>
        <name>Rocha, Luis M</name>
      </author>
    </item>
    <item>
      <title>The Dilemma of Building Do-It-Yourself (DIY) Solutions For Workplace Accessibility</title>
      <link>https://escholarship.org/uc/item/4hb4p499</link>
      <description>The Dilemma of Building Do-It-Yourself (DIY) Solutions For Workplace Accessibility</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4hb4p499</guid>
      <pubDate>Wed, 7 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Cha, Yoonha</name>
      </author>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>Kohl, Karina</name>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
      <author>
        <name>Branham, Stacy</name>
      </author>
    </item>
    <item>
      <title>Understanding the Career Mobility of Blind and Low Vision Software Professionals</title>
      <link>https://escholarship.org/uc/item/3284n9qx</link>
      <description>Context: Scholars in the software engineering (SE) research community have investigated career advancement in the software industry. Research topics have included how individual and external factors can impact career mobility of software professionals, and how gender affects career advancement. However, the community has yet to look at career mobility from the lens of accessibility. Specifically, there is a pressing need to illuminate the factors that hinder the career mobility of blind and low vision software professionals (BLVSPs). Objective: This study aims to understand aspects of the workplace that impact career mobility for BLVSPs. Methods: We interviewed 26 BLVSPs with different roles, years of experience, and industry sectors. Thematic analysis was used to identify common factors related to career mobility. Results: We found four factors that impacted the career mobility of BLVSPs: (1) technical challenges, (2) colleagues' perceptions of BLVSPs, (3) BLVSPs' own perceptions...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3284n9qx</guid>
      <pubDate>Wed, 7 May 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Cha, Yoonha</name>
      </author>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>Figueira, Isabela</name>
      </author>
      <author>
        <name>Branham, Stacy Marie</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
    </item>
    <item>
      <title>Introduction to the Special Issue on Creativity in Software Engineering</title>
      <link>https://escholarship.org/uc/item/24k1h8b8</link>
      <description>Introduction to the Special Issue on Creativity in Software Engineering</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/24k1h8b8</guid>
      <pubDate>Wed, 23 Apr 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>van der Hoek, Andr</name>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
      </author>
      <author>
        <name>Singh, Kuldeep</name>
      </author>
    </item>
    <item>
      <title>Physician documentation matters. Using natural language processing to predict mortality in sepsis</title>
      <link>https://escholarship.org/uc/item/15t8q615</link>
      <description>Background/objective: Sepsis remains without good outcome prediction. Technological advances, specifically, natural language processing (NLP), has an opportunity to approach sepsis mortality prediction in a novel way.
Methods: Using the MIMIC III dataset, patients diagnosed with sepsis from 2008 to 2013 had physician progress notes analyzed using NLP. Researchers utilized concepts from analysis to build a model to predict for in-hospital-mortality, using notes in the first 24 hours of a patient admission. This model was retrospectively validated on septic admissions to University of California Irvine Medical Center (UCIMC) from 2013 to 2018 and compared to SOFA and qSOFA.
Results: An 80-concept model was developed and validated on 7117 admissions to UCIMC. For severe sepsis, an Area Under Curve or AUC of 0.687 (95% CI 0.618-0.748) was demonstrated which was greater than SOFA at 0.571 (0.497-0.643). Additionally, for simple sepsis the model demonstrated an AUC of 0.696 (0.649-0.738)...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/15t8q615</guid>
      <pubDate>Fri, 11 Apr 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Cooley-Rieders, Keaton</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
    </item>
    <item>
      <title>Modifying Curriculum for Novice Computational Thinking Elementary Teachers and English Language Learners</title>
      <link>https://escholarship.org/uc/item/2913b8g6</link>
      <description>The demand for computational thinking (CT) problem solving abilities surge as every aspect of life becomes more dependent on complex digital technologies. Just as in math and language, a strong CT foundation needs to be established in early education in order for students to develop an instinctive CT perspective of the world. The urgent demand for CT instruction in elementary school quickly draws attention to the shortage of elementary school-level teachers qualified and interested in CT. Additionally, with a commitment to equity in the United States education system and knowledge of the high percentage of English language learning (ELL) students in schools, the obligation to create curricula that will provide access to CT knowledge, skills, and practices for elementary-level ELL students is loudly apparent. In response to these two needs, our team has adapted existing Scratch-based CT curriculum to support classroom teachers with minimal CT experience and to be more accessible...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2913b8g6</guid>
      <pubDate>Wed, 9 Apr 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Saito-Stehberger, Dana</name>
      </author>
      <author>
        <name>Garcia, Leiny</name>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
    </item>
    <item>
      <title>University students describe how they adopt AI for writing and research in a general education course</title>
      <link>https://escholarship.org/uc/item/4dz427x8</link>
      <description>University students have begun to use Artificial Intelligence (AI) in many different ways in their undergraduate education, some beneficial to their learning, and some simply expedient to completing assignments with as little work as possible. This exploratory qualitative study examines how undergraduate students used AI in a large General Education course on sustainability and technology at a research university in the United States in 2023. Thirty-nine students documented their use of AI in their final course project, which involved analyzing conceptual networks connecting core sustainability concepts. Through iterative qualitative coding, we identified key patterns in students’ AI use, including higher-order writing tasks (understanding complex topics, finding evidence), lower-order writing tasks (revising, editing, proofreading), and other learning activities (efficiency enhancement, independent research). Students primarily used AI to improve communication of their original...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4dz427x8</guid>
      <pubDate>Fri, 4 Apr 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Black, Rebecca W</name>
        <uri>https://orcid.org/0000-0003-2412-6217</uri>
      </author>
      <author>
        <name>Tomlinson, Bill</name>
      </author>
    </item>
    <item>
      <title>Hate speech and hate-based harassment in online games</title>
      <link>https://escholarship.org/uc/item/5rr929gx</link>
      <description>The proliferation of hate speech and hate-based harassment has become a worryingly common trend in online gaming spaces, with researchers fearing that it could lead to the normalization of hateful behaviors on such platforms. However, little research has been done assessing the frequency of such events and how players respond to their occurrence. In this study, we conduct a large-scale survey (&lt;i&gt;n&lt;/i&gt; = 602) asking players to reflect on their experiences and responses to hateful conduct in online games. We examine their perspectives when faced with hate speech and harassment from the role of a bystander, a victim, or the perpetrator. We then compare these responses with various demographic factors and personality traits to determine which variables might predict such conduct to occur and persist over time. Our findings suggest that hate speech and harassment are more accepted by those who are not directly targeted, potentially leaving those players as the remaining few to continue...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5rr929gx</guid>
      <pubDate>Wed, 26 Mar 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Wells, Garrison</name>
      </author>
      <author>
        <name>Romhányi, Ágnes</name>
      </author>
      <author>
        <name>Steinkuehler, Constance</name>
      </author>
    </item>
    <item>
      <title>Intergenerational Effects of a Family Cash Transfer on the Home Environment</title>
      <link>https://escholarship.org/uc/item/2c8844fw</link>
      <description>OBJECTIVE: A natural experiment that provided income supplements to families has been associated with beneficial outcomes for children that persisted into adulthood. The children in this study are now adults, and many are parents.
METHOD: The study builds on the longitudinal, representative Great Smoky Mountains study conducted from 1993 to 2020. At follow-up in their late 30s, 1,094 of the 1,348 living participants (81.2%) were assessed. Of these participants (67.6%), 739 were parents. A tribe in the area implemented a cash transfer program of approximately $5,000 annually per person to every tribal member based on the profits received from operating a casino. Ten aspects of the home environment of participants were assessed (eg, family chaos, substance use, and food insecurity) as well as a composite measure across all home environment indicators. The proposed analyses were preregistered (https://osf.io/ex638).
RESULTS: Of the 739 parents assessed, 192 (26.0%) were American...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2c8844fw</guid>
      <pubDate>Tue, 18 Mar 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Copeland, William E</name>
      </author>
      <author>
        <name>Tong, Guangyu</name>
      </author>
      <author>
        <name>Shanahan, Lilly</name>
      </author>
      <author>
        <name>Rothenberg, W Andrew</name>
      </author>
      <author>
        <name>Lansford, Jennifer E</name>
      </author>
      <author>
        <name>Godwin, Jennifer W</name>
      </author>
      <author>
        <name>Rybińska, Anna</name>
      </author>
      <author>
        <name>Odgers, Candice L</name>
        <uri>https://orcid.org/0000-0003-4937-6618</uri>
      </author>
      <author>
        <name>Dodge, Kenneth A</name>
      </author>
    </item>
    <item>
      <title>Hybrid 3D Package with RDL and Laminate Substrate for Ultra-Thin and High-Bandwidth Applications</title>
      <link>https://escholarship.org/uc/item/8cr6s86r</link>
      <description>In this work, a hybrid 3D package combining a redistribution layer (RDL) and laminate substrate layer for ultra-thin and high-bandwidth mobile applications are discussed and demonstrated. The motivation behind this hybrid 3D package structure was leveraging the advantages of high density RDL layer and advanced laminate substrate layer in one package to optimize package features or performance in bandwidth, package height, assembly manufacturing and package level as well as board level reliability to each specific industry requirement. For demonstration purposes, a 12.5× 12.5-mm hybrid 3D packages combining a high density RDL and advanced laminate-substrate layer were designed and manufactured. In this demonstration, the 12.5× 12.5-mm hybrid 3D package showed 395 ? m package height including ball grid array (BGA) solder ball height and package warpage of $+64 ? m (in crying mode) at 25°C and-81 ? m (in smile mode) at 260°C. The demonstration package passed package level reliability...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8cr6s86r</guid>
      <pubDate>Wed, 5 Mar 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Kim, JY</name>
      </author>
      <author>
        <name>Kim, KR</name>
      </author>
      <author>
        <name>Lee, EY</name>
      </author>
      <author>
        <name>Hong, SH</name>
      </author>
      <author>
        <name>Shin, JH</name>
      </author>
      <author>
        <name>Lee, MK</name>
      </author>
      <author>
        <name>Lee, JH</name>
      </author>
      <author>
        <name>Hiner, D</name>
      </author>
      <author>
        <name>Do, WC</name>
      </author>
    </item>
    <item>
      <title>Chip-Last HDFO (High-Density Fan-Out) Interposer-PoP</title>
      <link>https://escholarship.org/uc/item/836496zg</link>
      <description>Interposer Package-on-Package (PoP) technology was developed and has been in very high-volume production over the last several years for high-end mobile application processors (APs). This is due to its advantages of good package design flexibility, controllable package warpage at room temperature (25°C) and high temperature (260°C), reduced assembly manufacturing cycle time and chip-last assembly manufacturing availability. To date, the laminate-substrate based interposer-PoP has been employed for high-end mobile APs with very high-volume production. Recently, this interposer-PoP design has faced some technical limitations including the need to reduce: top and bottom routing layer thickness, copper (Cu) trace line/space and via size for next generation mobile APs. These reductions may require ultra-thin package z-height and high-bandwidth bottom and top routing layers. To address these challenges, a new interposer-PoP with High-Density Fan-Out (HDFO) redistribution layer (RDL)...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/836496zg</guid>
      <pubDate>Wed, 5 Mar 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Kim, JY</name>
      </author>
      <author>
        <name>Kim, KR</name>
      </author>
      <author>
        <name>Lee, EY</name>
      </author>
      <author>
        <name>Hong, SH</name>
      </author>
      <author>
        <name>Kim, JH</name>
      </author>
      <author>
        <name>Ryu, JY</name>
      </author>
      <author>
        <name>Lee, JH</name>
      </author>
      <author>
        <name>Hiner, D</name>
      </author>
      <author>
        <name>Do, WC</name>
      </author>
      <author>
        <name>Khim, JY</name>
      </author>
    </item>
    <item>
      <title>Multimodal Pain Recognition in Postoperative Patients: Machine Learning Approach</title>
      <link>https://escholarship.org/uc/item/13m9x4rp</link>
      <description>BACKGROUND: Acute pain management is critical in postoperative care, especially in vulnerable patient populations that may be unable to self-report pain levels effectively. Current methods of pain assessment often rely on subjective patient reports or behavioral pain observation tools, which can lead to inconsistencies in pain management. Multimodal pain assessment, integrating physiological and behavioral data, presents an opportunity to create more objective and accurate pain measurement systems. However, most previous work has focused on healthy subjects in controlled environments, with limited attention to real-world postoperative pain scenarios. This gap necessitates the development of robust, multimodal approaches capable of addressing the unique challenges associated with assessing pain in clinical settings, where factors like motion artifacts, imbalanced label distribution, and sparse data further complicate pain monitoring.
OBJECTIVE: This study aimed to develop and evaluate...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/13m9x4rp</guid>
      <pubDate>Thu, 27 Feb 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Subramanian, Ajan</name>
      </author>
      <author>
        <name>Cao, Rui</name>
      </author>
      <author>
        <name>Naeini, Emad Kasaeyan</name>
      </author>
      <author>
        <name>Aqajari, Seyed Amir Hossein</name>
      </author>
      <author>
        <name>Hughes, Thomas D</name>
      </author>
      <author>
        <name>Calderon, Michael-David</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
      <author>
        <name>Dutt, Nikil</name>
        <uri>https://orcid.org/0000-0002-3060-8119</uri>
      </author>
      <author>
        <name>Liljeberg, Pasi</name>
      </author>
      <author>
        <name>Salanterä, Sanna</name>
      </author>
      <author>
        <name>Nelson, Ariana M</name>
        <uri>https://orcid.org/0000-0003-1575-1635</uri>
      </author>
      <author>
        <name>Rahmani, Amir M</name>
        <uri>https://orcid.org/0000-0003-0725-1155</uri>
      </author>
    </item>
    <item>
      <title>Exploring GenAI in Software Development: Insights from a Case Study in a Large Brazilian Company</title>
      <link>https://escholarship.org/uc/item/59h2f5hs</link>
      <description>Recent progress in Generative AI (GenAI) impacts different software engineering (ES) tasks in software development cycle, e.g., from code generation to program repair, and presents a promising avenue for enhancing the productivity of development teams. GenAI based tools have the potential to change the way we develop software and have received attention from industry and academia. However, although some studies have been addressing the adoption of these tools in the software industry, little is known about what are developers' real experiences in a professional software development context, aside the hype. In this paper, we explore the use of GenAI tools by a large Brazilian media company that has teams developing software inhouse. We observed practitioners for six weeks and used online surveys at different time points to understand their expectations, perceptions, and concerns about these tools in their daily work. In addition, we automatically collected quantitative data from...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/59h2f5hs</guid>
      <pubDate>Wed, 22 Jan 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Pereira, Guilherme Vaz</name>
      </author>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
      <author>
        <name>Fortes, Luciane</name>
      </author>
      <author>
        <name>Araújo, Carolina</name>
      </author>
      <author>
        <name>Coelho, André</name>
      </author>
      <author>
        <name>Chelli, Ligia</name>
      </author>
      <author>
        <name>Ramos, Diego</name>
      </author>
    </item>
    <item>
      <title>On meetings involving remote software teams: A systematic literature review</title>
      <link>https://escholarship.org/uc/item/38k352sp</link>
      <description>Context: The adoption of remote work models and the global nature of software projects have significantly transformed collaboration and communication within the software development industry. Remote meetings have become a common means of collaboration for software development teams. Objective: This study seeks to enhance our understanding of remote meeting practices in software teams. It identifies the benefits of remote meetings, the problems associated with remote meetings, tools used to facilitate remote meetings and provides recommended good practices. The study employs a systematic literature review to assist remote teams in improving their meeting practices and identifying areas for future research. Methods: We conducted a systematic literature review that involved searching multiple databases and employing quantitative and qualitative analysis techniques on the identified set of studies to answer our research questions. Results: The search yielded 30 papers offering valuable...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/38k352sp</guid>
      <pubDate>Fri, 17 Jan 2025 00:00:00 +0000</pubDate>
      <author>
        <name>de Andrade, Anielle SL</name>
      </author>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
    </item>
    <item>
      <title>The Impact of Generative AI on Creativity in Software Development: A Research Agenda</title>
      <link>https://escholarship.org/uc/item/7t86q5ck</link>
      <description>As GenAI becomes embedded in developer toolchains and practices, and routine code is increasingly generated, human creativity will be increasingly important for generating competitive advantage. This paper uses the McLuhan tetrad alongside scenarios of how GenAI may disrupt software development more broadly, to identify potential impacts GenAI may have on creativity within software development. The impacts are discussed along with a future research agenda comprising five connected themes that consider how individual capabilities, team capabilities, the product, unintended consequences, and society. can be affected.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7t86q5ck</guid>
      <pubDate>Wed, 15 Jan 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Jackson, Victoria</name>
      </author>
      <author>
        <name>Vasilescu, Bogdan</name>
      </author>
      <author>
        <name>Russo, Daniel</name>
      </author>
      <author>
        <name>Ralph, Paul</name>
      </author>
      <author>
        <name>Izadi, Maliheh</name>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
      </author>
      <author>
        <name>D’angelo, Sarah</name>
      </author>
      <author>
        <name>Inman, Sarah</name>
      </author>
      <author>
        <name>Andrade, Anielle</name>
      </author>
      <author>
        <name>van der Hoek, André</name>
      </author>
    </item>
    <item>
      <title>Ma11y: A Mutation Framework for Web Accessibility Testing</title>
      <link>https://escholarship.org/uc/item/6wm923wc</link>
      <description>Despite the availability of numerous automatic accessibility testing solutions, web accessibility issues persist on many websites. Moreover, there is a lack of systematic evaluations of the efficacy of current accessibility testing tools. To address this gap, we present the first mutation analysis framework, called Ma11y, designed to assess web accessibility testing tools. Ma11y includes 25 mutation operators that intentionally violate various accessibility principles and an automated oracle to determine whether a mutant is detected by a testing tool. Evaluation on real-world websites demonstrates the practical applicability of the mutation operators and the framework's capacity to assess tool performance. Our results demonstrate that the current tools cannot identify nearly 50% of the accessibility bugs injected by our framework, thus underscoring the need for the development of more effective accessibility testing tools. Finally, the framework's accuracy and performance attest...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6wm923wc</guid>
      <pubDate>Wed, 15 Jan 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Tafreshipour, Mahan</name>
      </author>
      <author>
        <name>Deshpande, Anmol</name>
      </author>
      <author>
        <name>Mehralian, Forough</name>
      </author>
      <author>
        <name>Ahmed, Iftekhar</name>
      </author>
      <author>
        <name>Malek, Sam</name>
      </author>
    </item>
    <item>
      <title>The Reach, Effectiveness, Adoption, Implementation, and Maintenance of Digital Mental Health Interventions for College Students: A Systematic Review</title>
      <link>https://escholarship.org/uc/item/43t654rk</link>
      <description>Purpose of ReviewWe evaluated the impact of digital mental health interventions (DMHIs) for college students. We organized findings using the RE-AIM framework to include reach, effectiveness, adoption, implementation, and maintenance.Recent FindingsWe conducted a systematic literature review of recent findings from 2019–2024. Our search identified 2,701 articles, of which 95 met inclusion criteria. In the reach domain, student samples were overwhelmingly female and White. In the effectiveness domain, over 80% of DMHIs were effective or partially effective at reducing their primary outcome. In the adoption domain, studies reported modest uptake for DMHIs. In the implementation and maintenance domains, studies reported high adherence rates to DMHI content. While recruitment methods were commonly reported, adaptations and costs of implementation and maintenance were rarely reported.SummaryDMHIs for college students are effective for many psychological outcomes. Future work should...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/43t654rk</guid>
      <pubDate>Mon, 13 Jan 2025 00:00:00 +0000</pubDate>
      <author>
        <name>Taylor, Madison E</name>
      </author>
      <author>
        <name>Liu, Michelle</name>
      </author>
      <author>
        <name>Abelson, Sara</name>
      </author>
      <author>
        <name>Eisenberg, Daniel</name>
      </author>
      <author>
        <name>Lipson, Sarah K</name>
      </author>
      <author>
        <name>Schueller, Stephen M</name>
        <uri>https://orcid.org/0000-0002-1003-0399</uri>
      </author>
    </item>
    <item>
      <title>Leveraging Feedback From Families of Children With Autism to Create Digital Support for Service Navigation: Descriptive Study.</title>
      <link>https://escholarship.org/uc/item/84w423ht</link>
      <description>BACKGROUND: It is difficult for families to navigate and access services for their children with autism. Barriers to service access are compounded among families from low-resourced backgrounds. OBJECTIVE: The purpose of our study was to explore the development of an app to facilitate access to services among families of children with autism from low-resourced backgrounds. Our specific aims were to explore feedback from an advisory board about the app and to explore feedback from navigators about the app. METHODS: Via a multistage codevelopment process, we elicited feedback from 5 key parties: the research team, a community organization, the app development team, the advisory board, and family navigators. Collectively, 36 individuals provided feedback about the development of the app via individual interviews, focus groups, observations, and surveys. The key features of the app included a dashboard showing the service needs of the family and related resources, a messaging feature...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/84w423ht</guid>
      <pubDate>Fri, 13 Dec 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Burke, Meghan</name>
      </author>
      <author>
        <name>Li, Chak</name>
      </author>
      <author>
        <name>Cheung, Waifong</name>
      </author>
      <author>
        <name>Terol, Adriana</name>
      </author>
      <author>
        <name>Johnston, Amanda</name>
      </author>
      <author>
        <name>Schueller, Stephen</name>
      </author>
    </item>
    <item>
      <title>Adolescents’ Digital Technology Use, Emotional Dysregulation, and Self-Esteem: No Evidence of Same-Day Linkages</title>
      <link>https://escholarship.org/uc/item/4g13q77r</link>
      <description>Concerns regarding the potential negative impacts of digital technology use on youth mental health and well-being are high. However, most studies have several methodological limitations: relying on cross-sectional designs and retrospective reports, assessing technology use as an omnibus construct, and focusing on between- instead of within-person comparisons. This study addresses these limitations by prospectively following young adolescents (n = 388) over a 14-day ecological momentary assessment study to test whether adolescents’ digital technology use is linked with self-reported emotional dysregulation and self-esteem and whether these relationships are stronger for adolescent girls than boys. We found no evidence that adolescents experienced higher emotional dysregulation (b = − .02; p = .07) and lower self-esteem (b = .004; p = .32) than they normally do on days where they use more technology than they normally do (within-person). Adolescents with higher average daily technology...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4g13q77r</guid>
      <pubDate>Wed, 11 Dec 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Taylor, Madison E</name>
      </author>
      <author>
        <name>Schueller, Stephen M</name>
        <uri>https://orcid.org/0000-0002-1003-0399</uri>
      </author>
      <author>
        <name>Russell, Michael A</name>
      </author>
      <author>
        <name>Hoyle, Rick H</name>
      </author>
      <author>
        <name>Odgers, Candice L</name>
        <uri>https://orcid.org/0000-0003-4937-6618</uri>
      </author>
    </item>
    <item>
      <title>Self‐regulation and comprehension in shared reading: The moderating effects of verbal interactions and E‐book discussion prompts</title>
      <link>https://escholarship.org/uc/item/1bj8q0ts</link>
      <description>The study examined how children's self-regulation skills measured by the strengths and weaknesses of ADHD symptoms and normal behavior rating are associated with story comprehension and how verbal engagement and e-book discussion prompts moderate this relation. Children aged 3-7 (N = 111, 50% female, Chinese as first language) read an interactive Chinese-English bilingual story e-book with or without discussion prompts twice with their parents (2020-2021). Results demonstrated that the lower children's self-regulation skills, the more they struggled with story comprehension. Critically, our data suggest that embedding e-book discussion prompts and more verbalization in English can mitigate this negative association for children with inattention/hyperactivity. These findings have critical implications for future e-book design, interventions, and home reading practice for children with inattention/hyperactivity and those at risk for attention deficit/hyperactivity disorder.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1bj8q0ts</guid>
      <pubDate>Wed, 27 Nov 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Yang, Dandan</name>
      </author>
      <author>
        <name>Ge, Yan</name>
      </author>
      <author>
        <name>Sun, Yiwen</name>
      </author>
      <author>
        <name>Collins, Penelope</name>
        <uri>https://orcid.org/0000-0002-0818-3230</uri>
      </author>
      <author>
        <name>Jaeggi, Susanne M</name>
      </author>
      <author>
        <name>Xu, Ying</name>
      </author>
      <author>
        <name>Shea, Zhiling Meng</name>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
    </item>
    <item>
      <title>Reconciling the contrasting narratives on the environmental impact of large language models</title>
      <link>https://escholarship.org/uc/item/76c529tr</link>
      <description>The recent proliferation of large language models (LLMs) has led to divergent narratives about their environmental impacts. Some studies highlight the substantial carbon footprint of training and using LLMs, while others argue that LLMs can lead to more sustainable alternatives to current practices. We reconcile these narratives by presenting a comparative assessment of the environmental impact of LLMs vs. human labor, examining their relative efficiency across energy consumption, carbon emissions, water usage, and cost. Our findings reveal that, while LLMs have substantial environmental impacts, their relative impacts can be dramatically lower than human labor in the U.S. for the same output, with human-to-LLM ratios ranging from 40 to 150 for a typical LLM (Llama-3-70B) and from 1200 to 4400 for a lightweight LLM (Gemma-2B-it). While the human-to-LLM ratios are smaller with regard to human labor in India, these ratios are still between 3.4 and 16 for a typical LLM and between...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/76c529tr</guid>
      <pubDate>Thu, 21 Nov 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Ren, Shaolei</name>
        <uri>https://orcid.org/0000-0001-9003-4324</uri>
      </author>
      <author>
        <name>Tomlinson, Bill</name>
      </author>
      <author>
        <name>Black, Rebecca W</name>
        <uri>https://orcid.org/0000-0003-2412-6217</uri>
      </author>
      <author>
        <name>Torrance, Andrew W</name>
      </author>
    </item>
    <item>
      <title>Evaluation of a pilot implementation of a digital cognitive behavioral therapy platform for isolated older adults in county mental health services</title>
      <link>https://escholarship.org/uc/item/2nw6n3b5</link>
      <description>Background: Technology-enabled services (TESs) have the potential to increase access to mental healthcare. However, little research has focused on how TESs can be integrated into publicly funded service settings. As part of the state-wide Help@Hand project, Marin County conducted a pilot implementation of myStrength, a digital cognitive behavioral therapy platform, to explore its potential to reduce loneliness among isolated older adults. We evaluated the pilot impact using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework.
Method: A single-site 6-month pilot implementation recruited English (&lt;i&gt;n&lt;/i&gt; = 15) and Spanish-speaking (&lt;i&gt;n&lt;/i&gt; = 15) isolated older adults who received a digital literacy course followed by 8 weeks of myStrength access and human support. We evaluated factors related to reach, effectiveness, adoption, and implementation using the perspectives of users and County staff. Descriptive statistics were used to examine reach,...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2nw6n3b5</guid>
      <pubDate>Mon, 11 Nov 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Hernandez-Ramos, Rosa</name>
      </author>
      <author>
        <name>Schueller, Stephen M</name>
      </author>
      <author>
        <name>Borghouts, Judith</name>
      </author>
      <author>
        <name>Palomares, Kristina</name>
      </author>
      <author>
        <name>Eikey, Elizabeth</name>
      </author>
      <author>
        <name>Schneider, Margaret</name>
        <uri>https://orcid.org/0000-0002-8314-0732</uri>
      </author>
      <author>
        <name>Stadnick, Nicole A</name>
        <uri>https://orcid.org/0000-0001-6520-2920</uri>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
      <author>
        <name>Mukamel, Dana B</name>
        <uri>https://orcid.org/0000-0003-4147-5785</uri>
      </author>
      <author>
        <name>Sorkin, Dara H</name>
        <uri>https://orcid.org/0000-0003-0742-9240</uri>
      </author>
    </item>
    <item>
      <title>Mother-child and father-child “serve and return” interactions at 9 months: Associations with children’s language skills at 18 and 24 months</title>
      <link>https://escholarship.org/uc/item/9cc4892m</link>
      <description>Infants learn language through the back-and-forth interactions with their parents where they "serve" by uttering sounds, gesturing, or looking and parents "return" in prompt (i.e., close in time) and meaningful (i.e., semantically relevant to the object of interest) ways. In a sample of 9-month-old infants (n&amp;nbsp;=&amp;nbsp;148) and their mothers and fathers (n&amp;nbsp;=&amp;nbsp;296 parents) from ethnically and socioeconomically diverse backgrounds, we examined the associations between "serve and return" (SR) parent-child interactions and children's language skills at 18 and 24 months. We also examined the moderation effects between maternal and paternal SR interactions on language outcomes. SR interactions were transcribed and coded from videotaped parent-child toy play activities during home visits. We report three findings. First, mothers who provided more meaningful responses to their child's serves at 9 months had children with higher expressive language scores at 18 months. Second,...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9cc4892m</guid>
      <pubDate>Sat, 9 Nov 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Chen, Yu</name>
      </author>
      <author>
        <name>Cabrera, Natasha J</name>
      </author>
      <author>
        <name>Reich, Stephanie M</name>
        <uri>https://orcid.org/0000-0002-8799-5236</uri>
      </author>
    </item>
    <item>
      <title>Intergenerational effects of a casino-funded family transfer program on educational outcomes in an American Indian community</title>
      <link>https://escholarship.org/uc/item/7vb0r4f2</link>
      <description>Cash transfer policies have been widely discussed as mechanisms to curb intergenerational transmission of socioeconomic disadvantage. In this paper, we take advantage of a large casino-funded family transfer program introduced in a Southeastern American Indian Tribe to generate difference-in-difference estimates of the link between children’s cash transfer exposure and third grade math and reading test scores of their offspring. Here we show greater math (0.25 standard deviation [SD], p =.0148, 95% Confidence Interval [CI]: 0.05, 0.45) and reading (0.28 SD, p = .0066, 95% CI: 0.08, 0.49) scores among American Indian students whose mother was exposed ten years longer than other American Indian students to the cash transfer during her childhood (or relative to the non-American Indian student referent group). Exploratory analyses find that a mother’s decision to pursue higher education and delay fertility appears to explain some, but not all, of the relation between cash transfers...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7vb0r4f2</guid>
      <pubDate>Tue, 5 Nov 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Bruckner, Tim A</name>
      </author>
      <author>
        <name>Bustos, Brenda</name>
      </author>
      <author>
        <name>Dodge, Kenneth A</name>
      </author>
      <author>
        <name>Lansford, Jennifer E</name>
      </author>
      <author>
        <name>Odgers, Candice L</name>
        <uri>https://orcid.org/0000-0003-4937-6618</uri>
      </author>
      <author>
        <name>Copeland, William E</name>
      </author>
    </item>
    <item>
      <title>Electronic Bridge to Mental Health for College Students: A Randomized Controlled Intervention Trial</title>
      <link>https://escholarship.org/uc/item/5j35j8h7</link>
      <description>OBJECTIVE: Suicide is the second leading cause of death among college students in the United States, and the percentage of students reporting suicidal thoughts is increasing. Nevertheless, many students at risk do not seek mental health (MH) services. This randomized controlled trial (RCT) examined the efficacy of Electronic Bridge to Mental Health for College Students (eBridge) for increasing at-risk students' linkage to MH services.
METHOD: Students from four universities were recruited via email; 40,347 (22.6%) completed the online suicide risk screen; and 3,363 (8.3%) met criteria for randomization based on suicide risk factors and lack of current treatment (62.2% female, 35.0% male, 2.8% transgender/nonbinary; 73.2% White, 7.0% Black, 19.9% Asian, 11.7% other; 12.4% Hispanic, 76.2% undergraduate). These students were randomized to eBridge [personalized feedback (PF) with option of online counseling] or Control (PF). The primary outcome was linkage to MH services within 6...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5j35j8h7</guid>
      <pubDate>Wed, 30 Oct 2024 00:00:00 +0000</pubDate>
      <author>
        <name>King, Cheryl A</name>
      </author>
      <author>
        <name>Eisenberg, Daniel</name>
      </author>
      <author>
        <name>Pistorello, Jacqueline</name>
      </author>
      <author>
        <name>Coryell, William</name>
      </author>
      <author>
        <name>Albucher, Ronald C</name>
      </author>
      <author>
        <name>Favorite, Todd</name>
      </author>
      <author>
        <name>Horwitz, Adam</name>
      </author>
      <author>
        <name>Bonar, Erin E</name>
      </author>
      <author>
        <name>Epstein, Daniel</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
    </item>
    <item>
      <title>The effect of SARS-COV-2 variant on non-respiratory features and mortality among vaccinated and non-fully vaccinated patients</title>
      <link>https://escholarship.org/uc/item/8cj316ff</link>
      <description>OBJECTIVE: To determine the effect of SARS-CoV-2 variants on non-respiratory features of COVID-19 in vaccinated and not fully vaccinated patients using a University of California database.
METHODS: A longitudinal retrospective review of medical records (n&amp;nbsp;=&amp;nbsp;63,454) from 1/1/2020-4/26/2022 using the UCCORDS database was performed to compare non-respiratory features, vaccination status, and mortality between variants. Chi-square tests were used to study the relationship between categorical variables using a contingency matrix.
RESULTS: Fever was the most common feature across all variants. Fever was significantly higher in not fully vaccinated during the Delta and Omicron waves (p&amp;nbsp;=&amp;nbsp;0.001; p&amp;nbsp;=&amp;nbsp;0.001). Cardiac features were statistically higher in not fully vaccinated during Omicron; tachycardia was only a feature of not fully vaccinated during Delta and Omicron; diabetes and GI reflux were features of all variants regardless of vaccine status. Odds...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8cj316ff</guid>
      <pubDate>Tue, 29 Oct 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Cotton, Shannon A</name>
      </author>
      <author>
        <name>Subramanian, Ajan</name>
      </author>
      <author>
        <name>Hughes, Thomas D</name>
      </author>
      <author>
        <name>Huang, Yong</name>
      </author>
      <author>
        <name>Sierra, Carmen Josefa</name>
      </author>
      <author>
        <name>Pearce, Alex K</name>
      </author>
      <author>
        <name>Malhotra, Atul</name>
      </author>
      <author>
        <name>Rahmani, Amir M</name>
        <uri>https://orcid.org/0000-0003-0725-1155</uri>
      </author>
      <author>
        <name>Downs, Charles A</name>
      </author>
      <author>
        <name>Pinto, Melissa D</name>
      </author>
    </item>
    <item>
      <title>Hidden flaws behind expert-level accuracy of multimodal GPT-4 vision in medicine</title>
      <link>https://escholarship.org/uc/item/5cj5w41r</link>
      <description>Recent studies indicate that Generative Pre-trained Transformer 4 with Vision (GPT-4V) outperforms human physicians in medical challenge tasks. However, these evaluations primarily focused on the accuracy of multi-choice questions alone. Our study extends the current scope by conducting a comprehensive analysis of GPT-4V’s rationales of image comprehension, recall of medical knowledge, and step-by-step multimodal reasoning when solving New England Journal of Medicine (NEJM) Image Challenges—an imaging quiz designed to test the knowledge and diagnostic capabilities of medical professionals. Evaluation results confirmed that GPT-4V performs comparatively to human physicians regarding multi-choice accuracy (81.6% vs. 77.8%). GPT-4V also performs well in cases where physicians incorrectly answer, with over 78% accuracy. However, we discovered that GPT-4V frequently presents flawed rationales in cases where it makes the correct final choices (35.5%), most prominent in image comprehension...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5cj5w41r</guid>
      <pubDate>Fri, 11 Oct 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Jin, Qiao</name>
      </author>
      <author>
        <name>Chen, Fangyuan</name>
      </author>
      <author>
        <name>Zhou, Yiliang</name>
        <uri>https://orcid.org/0009-0002-7457-7075</uri>
      </author>
      <author>
        <name>Xu, Ziyang</name>
      </author>
      <author>
        <name>Cheung, Justin M</name>
      </author>
      <author>
        <name>Chen, Robert</name>
      </author>
      <author>
        <name>Summers, Ronald M</name>
      </author>
      <author>
        <name>Rousseau, Justin F</name>
      </author>
      <author>
        <name>Ni, Peiyun</name>
      </author>
      <author>
        <name>Landsman, Marc J</name>
      </author>
      <author>
        <name>Baxter, Sally L</name>
        <uri>https://orcid.org/0000-0002-5271-7690</uri>
      </author>
      <author>
        <name>Al’Aref, Subhi J</name>
      </author>
      <author>
        <name>Li, Yijia</name>
      </author>
      <author>
        <name>Chen, Alexander</name>
      </author>
      <author>
        <name>Brejt, Josef A</name>
      </author>
      <author>
        <name>Chiang, Michael F</name>
      </author>
      <author>
        <name>Peng, Yifan</name>
      </author>
      <author>
        <name>Lu, Zhiyong</name>
      </author>
    </item>
    <item>
      <title>Closing the gap between open source and commercial large language models for medical evidence summarization</title>
      <link>https://escholarship.org/uc/item/27c7660v</link>
      <description>Large language models (LLMs) hold great promise in summarizing medical evidence. Most recent studies focus on the application of proprietary LLMs. Using proprietary LLMs introduces multiple risk factors, including a lack of transparency and vendor dependency. While open-source LLMs allow better transparency and customization, their performance falls short compared to the proprietary ones. In this study, we investigated to what extent fine-tuning open-source LLMs can further improve their performance. Utilizing a benchmark dataset, MedReview, consisting of 8161 pairs of systematic reviews and summaries, we fine-tuned three broadly-used, open-sourced LLMs, namely PRIMERA, LongT5, and Llama-2. Overall, the performance of open-source models was all improved after fine-tuning. The performance of fine-tuned LongT5 is close to GPT-3.5 with zero-shot settings. Furthermore, smaller fine-tuned models sometimes even demonstrated superior performance compared to larger zero-shot models. The...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/27c7660v</guid>
      <pubDate>Fri, 11 Oct 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Zhang, Gongbo</name>
      </author>
      <author>
        <name>Jin, Qiao</name>
      </author>
      <author>
        <name>Zhou, Yiliang</name>
        <uri>https://orcid.org/0009-0002-7457-7075</uri>
      </author>
      <author>
        <name>Wang, Song</name>
      </author>
      <author>
        <name>Idnay, Betina</name>
      </author>
      <author>
        <name>Luo, Yiming</name>
      </author>
      <author>
        <name>Park, Elizabeth</name>
      </author>
      <author>
        <name>Nestor, Jordan G</name>
      </author>
      <author>
        <name>Spotnitz, Matthew E</name>
      </author>
      <author>
        <name>Soroush, Ali</name>
      </author>
      <author>
        <name>Campion, Thomas R</name>
      </author>
      <author>
        <name>Lu, Zhiyong</name>
      </author>
      <author>
        <name>Weng, Chunhua</name>
      </author>
      <author>
        <name>Peng, Yifan</name>
      </author>
    </item>
    <item>
      <title>Xylem: An Energy-efficient, Globally Redistributive, Financial Infrastructure Using Proof-by-Location</title>
      <link>https://escholarship.org/uc/item/77c4b8ng</link>
      <description>The Proof-of-Work algorithm that underlies Bitcoin, Ethereum
            w
            ,
            
              1
            
            and many other cryptocurrencies is well known for its energy-intensive requirements. The Proof-of-Stake algorithm that underlies Ethereum&amp;nbsp;and various other cryptocurrencies is less impactful environmentally, but it has a second, looming issue: the problem of wealth inequality. We have developed an alternative to Proof-of-Work and Proof-of-Stake, called Proof-by-Location, that has the potential to address both of these issues. This article describes Proof-by-Location and a financial platform called Xylem that is based on it. This platform seeks to distribute transaction fees to billions of cryptocurrency “Notaries” around the world (essentially, anyone with a smartphone), who work together to establish a distributed consensus about financial transactions. In this article, we demonstrate that this platform can scale to more than 3.9...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/77c4b8ng</guid>
      <pubDate>Wed, 9 Oct 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Patterson, Donald Jay</name>
        <uri>https://orcid.org/0000-0001-8525-0495</uri>
      </author>
      <author>
        <name>Tomlinson, Bill</name>
      </author>
    </item>
    <item>
      <title>Player vs. Monster: The Making and Breaking of Videogame Monstrosity</title>
      <link>https://escholarship.org/uc/item/5m416586</link>
      <description>Player vs. Monster: The Making and Breaking of Videogame Monstrosity</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5m416586</guid>
      <pubDate>Wed, 31 Jul 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Krapp, Peter</name>
        <uri>https://orcid.org/0000-0002-2854-5403</uri>
      </author>
    </item>
    <item>
      <title>Review of Milestones in Analog and Digital Computing, 3rd ed by Herbert Bruderer</title>
      <link>https://escholarship.org/uc/item/0bj2176v</link>
      <description>The book presents the major milestones of analog and digital computing. It was first published in German in 2015, followed by a significantly expanded two volume edition in 2018, and the third edition boasts added material and is now also available in English. The author exhaustively covers mechanical calculators, historical automata, and scientific instruments. In its detailed account of analog computing, this volume is surely unrivaled-the book discusses many groundbreaking analog devices, from the Antikythera (the first known astronomical calculator) to the Curta (the smallest mechanical parallel calculator), before venturing into the electronic era. The author not only compiles a historical guide to computing, he also offers detailed lists and tables that classify machines systematically: according to their function, their national origins, or according to where extant machines are collected or exhibited. The more recent past of digital computing is similarly more complex...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0bj2176v</guid>
      <pubDate>Wed, 31 Jul 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Krapp, Peter</name>
        <uri>https://orcid.org/0000-0002-2854-5403</uri>
      </author>
    </item>
    <item>
      <title>Linguistic Features of Secondary School Writing: Can Natural Language Processing Shine a Light on Differences by Sex, English Language Status, or Higher Scoring Essays?</title>
      <link>https://escholarship.org/uc/item/1qg5529f</link>
      <description>This article provides three major contributions to the literature: we provide granular information on the development of student argumentative writing across secondary school; we replicate the MacArthur et al. model of Natural Language Processing (NLP) writing features that predict quality with a younger group of students; and we are able to examine the differences for students across language status. In our study, we sought to find the average levels of text length, cohesion, connectives, syntactic complexity, and word-level complexity in this sample across Grades 7-12 by sex, by English learner status, and for essays scoring above and below the median holistic score. Mean levels of variables by grade suggest a developmental progression with respect to text length, with the text length increasing with grade level, but the other variables in the model were fairly stable. Sex did not seem to affect the model in meaningful ways beyond the increased fluency of women writers. We saw...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1qg5529f</guid>
      <pubDate>Thu, 20 Jun 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Tate, Tamara P</name>
        <uri>https://orcid.org/0000-0002-1753-8435</uri>
      </author>
      <author>
        <name>Kim, Young-Suk Grace</name>
        <uri>https://orcid.org/0000-0002-4328-3843</uri>
      </author>
      <author>
        <name>Collins, Penelope</name>
        <uri>https://orcid.org/0000-0002-0818-3230</uri>
      </author>
      <author>
        <name>Warschauer, Mark</name>
        <uri>https://orcid.org/0000-0002-6817-4416</uri>
      </author>
      <author>
        <name>Olson, Carol Booth</name>
      </author>
    </item>
    <item>
      <title>Introduction &lt;i&gt;Algorithmic Rights and Protections for Children&lt;/i&gt;</title>
      <link>https://escholarship.org/uc/item/8f49284f</link>
      <description>Introduction &lt;i&gt;Algorithmic Rights and Protections for Children&lt;/i&gt;</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8f49284f</guid>
      <pubDate>Thu, 6 Jun 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Ito, Mizuko</name>
      </author>
      <author>
        <name>Cross, Remy</name>
      </author>
      <author>
        <name>Dinakar, Karthik</name>
      </author>
      <author>
        <name>Odgers, Candice</name>
      </author>
    </item>
    <item>
      <title>Early Results from a Study of GenAI Adoption in a Large Brazilian Company: The Case of Globo</title>
      <link>https://escholarship.org/uc/item/7rj985mc</link>
      <description>Early Results from a Study of GenAI Adoption in a Large Brazilian Company: The Case of Globo</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7rj985mc</guid>
      <pubDate>Thu, 6 Jun 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Pereira, Guilherme</name>
        <uri>https://orcid.org/0009-0006-3521-6081</uri>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
        <uri>https://orcid.org/0000-0003-3351-4916</uri>
      </author>
      <author>
        <name>Jackson, Victoria</name>
        <uri>https://orcid.org/0000-0002-6326-931X</uri>
      </author>
      <author>
        <name>van der Hoek, André</name>
        <uri>https://orcid.org/0000-0001-7917-932X</uri>
      </author>
      <author>
        <name>Fortes, Luciane</name>
      </author>
      <author>
        <name>Macaubas, Igor</name>
      </author>
    </item>
    <item>
      <title>Co-Designing Situated Displays for Family Co-Regulation with ADHD Children</title>
      <link>https://escholarship.org/uc/item/8mj0812z</link>
      <description>Co-Designing Situated Displays for Family Co-Regulation with ADHD Children</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8mj0812z</guid>
      <pubDate>Wed, 22 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Silva, Lucas M</name>
      </author>
      <author>
        <name>Cibrian, Franceli L</name>
      </author>
      <author>
        <name>Bonang, Clarisse</name>
      </author>
      <author>
        <name>Bhattacharya, Arpita</name>
      </author>
      <author>
        <name>Min, Aehong</name>
        <uri>https://orcid.org/0000-0002-3790-2126</uri>
      </author>
      <author>
        <name>Monteiro, Elissa M</name>
      </author>
      <author>
        <name>Beltran, Jesus Armando</name>
      </author>
      <author>
        <name>Schuck, Sabrina</name>
      </author>
      <author>
        <name>Lakes, Kimberley D</name>
      </author>
      <author>
        <name>Hayes, Gillian R</name>
      </author>
      <author>
        <name>Epstein, Daniel A</name>
        <uri>https://orcid.org/0000-0002-2657-6345</uri>
      </author>
    </item>
    <item>
      <title>Penalized Fieller's Confidence Interval for the Ratio of Bivariate Normal Means</title>
      <link>https://escholarship.org/uc/item/9q82m287</link>
      <description>Constructing a confidence interval for the ratio of bivariate normal means is a classical problem in statistics. Several methods have been proposed in the literature. The Fieller method is known as an exact method, but can produce an unbounded confidence interval if the denominator of the ratio is not significantly deviated from 0; while the delta and some numeric methods are all bounded, they are only first-order correct. Motivated by a real-world problem, we propose the penalized Fieller method, which employs the same principle as the Fieller method, but adopts a penalized likelihood approach to estimate the denominator. The proposed method has a simple closed form, and can always produce a bounded confidence interval by selecting a suitable penalty parameter. Moreover, the new method is shown to be second-order correct under the bivariate normality assumption, that is, its coverage probability will converge to the nominal level faster than other bounded methods. Simulation...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9q82m287</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Wang, Peng</name>
      </author>
      <author>
        <name>Xu, Siqi</name>
      </author>
      <author>
        <name>Wang, Yi-Xin</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Fung, Kam</name>
      </author>
      <author>
        <name>Gao, Guimin</name>
      </author>
      <author>
        <name>Liang, Zhijiang</name>
      </author>
      <author>
        <name>Liu, Nianjun</name>
      </author>
    </item>
    <item>
      <title>Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis</title>
      <link>https://escholarship.org/uc/item/83t6r9w2</link>
      <description>Elevations in peripheral inflammatory markers have been reported in patients with psychosis. Whether this represents an inflammatory process defined by individual or subgroups of markers is unclear. Further, relationships between peripheral inflammatory marker elevations and brain structure, cognition, and clinical features of psychosis remain unclear. We hypothesized that a pattern of plasma inflammatory markers, and an inflammatory subtype established from this pattern, would be elevated across the psychosis spectrum and associated with cognition and brain structural alterations. Clinically stable psychosis probands (Schizophrenia spectrum, n = 79; Psychotic Bipolar disorder, n = 61) and matched healthy controls (HC, n = 60) were assessed for 15 peripheral inflammatory markers, cortical thickness, subcortical volume, cognition, and symptoms. A combination of unsupervised exploratory factor analysis and hierarchical clustering was used to identify inflammation subtypes. Levels...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/83t6r9w2</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Lizano, Paulo</name>
      </author>
      <author>
        <name>Lutz, Olivia</name>
      </author>
      <author>
        <name>Xu, Yanxun</name>
      </author>
      <author>
        <name>Rubin, Leah H</name>
      </author>
      <author>
        <name>Paskowitz, Lyle</name>
      </author>
      <author>
        <name>Lee, Adam M</name>
      </author>
      <author>
        <name>Eum, Seenae</name>
      </author>
      <author>
        <name>Keedy, Sarah K</name>
      </author>
      <author>
        <name>Hill, S Kristian</name>
      </author>
      <author>
        <name>Reilly, James L</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Tamminga, Carol A</name>
      </author>
      <author>
        <name>Clementz, Brett A</name>
      </author>
      <author>
        <name>Pearlson, Godfrey D</name>
      </author>
      <author>
        <name>Gershon, Elliot S</name>
      </author>
      <author>
        <name>Keshavan, Matcheri S</name>
      </author>
      <author>
        <name>Sweeney, John A</name>
      </author>
      <author>
        <name>Bishop, Jeffrey R</name>
      </author>
    </item>
    <item>
      <title>CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism</title>
      <link>https://escholarship.org/uc/item/7k09z5dg</link>
      <description>Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 engineering of the &lt;i&gt;CYP3A5 *3&lt;/i&gt; locus (rs776746) in human liver cell line HuH-7 (&lt;i&gt;CYP3A5 *3/*3&lt;/i&gt;) has led to three &lt;i&gt;CYP3A5 *1&lt;/i&gt; cell lines by deletion of the exon 3B splice junction or point mutation. Cell lines &lt;i&gt;CYP3A5 *1/*3 sd&lt;/i&gt; (single deletion), &lt;i&gt;CYP3A5 *1/*1&lt;/i&gt; dd (double deletion), or &lt;i&gt;CYP3A5 *1/*3&lt;/i&gt; pm (point mutation) expressed the &lt;i&gt;CYP3A5 *1&lt;/i&gt; mRNA and had elevated &lt;i&gt;CYP3A5&lt;/i&gt; mRNA (&lt;i&gt;P&lt;/i&gt; &amp;lt; 0.0005 for all engineered cell lines) and protein expression compared with HuH-7. In metabolism assays, HuH-7 had less tacrolimus (all &lt;i&gt;P&lt;/i&gt; &amp;lt; 0.05) or midazolam (MDZ) (all &lt;i&gt;P&lt;/i&gt; &amp;lt; 0.005) disappearance than all engineered cell lines. HuH-7 had less 1-OH MDZ (all &lt;i&gt;P&lt;/i&gt; &amp;lt; 0.0005) or 4-OH (all &lt;i&gt;P&lt;/i&gt; &amp;lt; 0.005) production in metabolism assays than all bioengineered cell lines. We confirmed CYP3A5 metabolic activity with the CYP3A4 selective inhibitor CYP3CIDE....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7k09z5dg</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Dorr, Casey R</name>
      </author>
      <author>
        <name>Remmel, Rory P</name>
      </author>
      <author>
        <name>Muthusamy, Amutha</name>
      </author>
      <author>
        <name>Fisher, James</name>
      </author>
      <author>
        <name>Moriarity, Branden S</name>
      </author>
      <author>
        <name>Yasuda, Kazuto</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Guan, Weihua</name>
      </author>
      <author>
        <name>Schuetz, Erin G</name>
      </author>
      <author>
        <name>Oetting, William S</name>
      </author>
      <author>
        <name>Jacobson, Pamala A</name>
      </author>
      <author>
        <name>Israni, Ajay K</name>
      </author>
    </item>
    <item>
      <title>Proteome Profiling in Lung Injury after Hematopoietic Stem Cell Transplantation</title>
      <link>https://escholarship.org/uc/item/685342mz</link>
      <description>Pulmonary complications due to infection and idiopathic pneumonia syndrome (IPS), a noninfectious lung injury in hematopoietic stem cell transplant (HSCT) recipients, are frequent causes of transplantation-related mortality and morbidity. Our objective was to characterize the global bronchoalveolar lavage fluid (BALF) protein expression of IPS to identify proteins and pathways that differentiate IPS from infectious lung injury after HSCT. We studied 30 BALF samples from patients who developed lung injury within 180&amp;nbsp;days of HSCT or cellular therapy transfusion (natural killer cell transfusion). Adult subjects were classified as having IPS or infectious lung injury by the criteria outlined in the 2011 American Thoracic Society statement. BALF was depleted of hemoglobin and 14 high-abundance proteins, treated with trypsin, and labeled with isobaric tagging for relative and absolute quantification (iTRAQ) 8-plex reagent for two-dimensional capillary liquid chromatography (LC)...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/685342mz</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Bhargava, Maneesh</name>
      </author>
      <author>
        <name>Viken, Kevin J</name>
      </author>
      <author>
        <name>Dey, Sanjoy</name>
      </author>
      <author>
        <name>Steinbach, Michael S</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Jagtap, Pratik D</name>
      </author>
      <author>
        <name>Higgins, LeeAnn</name>
      </author>
      <author>
        <name>Panoskaltsis-Mortari, Angela</name>
      </author>
      <author>
        <name>Weisdorf, Daniel J</name>
      </author>
      <author>
        <name>Kumar, Vipin</name>
      </author>
      <author>
        <name>Arora, Mukta</name>
      </author>
      <author>
        <name>Bitterman, Peter B</name>
      </author>
      <author>
        <name>Ingbar, David H</name>
      </author>
      <author>
        <name>Wendt, Chris H</name>
      </author>
    </item>
    <item>
      <title>Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients</title>
      <link>https://escholarship.org/uc/item/67g7t13m</link>
      <description>The immunosuppressant tacrolimus (TAC) is metabolized by both cytochrome P450 3A4 (CYP3A4) and CYP3A5 enzymes. It is common for European Americans (EA) to carry two CYP3A5 loss-of-function (LoF) variants that profoundly reduces TAC metabolism. Despite having two LoF alleles, there is still considerable variability in TAC troughs and identifying additional variants in genes outside of the CYP3A5 gene could provide insight into this variability. We analyzed TAC trough concentrations in 1345 adult EA recipients with two CYP3A5 LoF alleles in a genome-wide association study. Only CYP3A4*22 was identified and no additional variants were genome-wide significant. Additional high allele frequency genetic variants with strong genetic effects associated with TAC trough variability are unlikely to be associated with TAC variation in the EA population. These data suggest that low allele frequency variants, identified by DNA sequencing, should be evaluated and may identify additional variants...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/67g7t13m</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Oetting, WS</name>
      </author>
      <author>
        <name>Wu, B</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Schladt, DP</name>
      </author>
      <author>
        <name>Guan, W</name>
      </author>
      <author>
        <name>Remmel, RP</name>
      </author>
      <author>
        <name>Mannon, RB</name>
      </author>
      <author>
        <name>Matas, AJ</name>
      </author>
      <author>
        <name>Israni, AK</name>
      </author>
      <author>
        <name>Jacobson, PA</name>
      </author>
    </item>
    <item>
      <title>Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies</title>
      <link>https://escholarship.org/uc/item/5x79k9tx</link>
      <description>BackgroundIn addition to HLA genetic incompatibility, non-HLA difference between donor and recipients of transplantation leading to allograft rejection are now becoming evident. We aimed to create a unique genome-wide platform to facilitate genomic research studies in transplant-related studies. We designed a genome-wide genotyping tool based on the most recent human genomic reference datasets, and included customization for known and potentially relevant metabolic and pharmacological loci relevant to transplantation.MethodsWe describe here the design and implementation of a customized genome-wide genotyping array, the ‘TxArray’, comprising approximately 782,000 markers with tailored content for deeper capture of variants across HLA, KIR, pharmacogenomic, and metabolic loci important in transplantation. To test concordance and genotyping quality, we genotyped 85 HapMap samples on the array, including eight trios.ResultsWe show low Mendelian error rates and high concordance rates...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5x79k9tx</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Li, Yun R</name>
      </author>
      <author>
        <name>van Setten, Jessica</name>
      </author>
      <author>
        <name>Verma, Shefali S</name>
      </author>
      <author>
        <name>Lu, Yontao</name>
      </author>
      <author>
        <name>Holmes, Michael V</name>
      </author>
      <author>
        <name>Gao, Hui</name>
      </author>
      <author>
        <name>Lek, Monkol</name>
      </author>
      <author>
        <name>Nair, Nikhil</name>
      </author>
      <author>
        <name>Chandrupatla, Hareesh</name>
      </author>
      <author>
        <name>Chang, Baoli</name>
      </author>
      <author>
        <name>Karczewski, Konrad J</name>
      </author>
      <author>
        <name>Wong, Chanel</name>
      </author>
      <author>
        <name>Mohebnasab, Maede</name>
      </author>
      <author>
        <name>Mukhtar, Eyas</name>
      </author>
      <author>
        <name>Phillips, Randy</name>
      </author>
      <author>
        <name>Tragante, Vinicius</name>
      </author>
      <author>
        <name>Hou, Cuiping</name>
      </author>
      <author>
        <name>Steel, Laura</name>
      </author>
      <author>
        <name>Lee, Takesha</name>
      </author>
      <author>
        <name>Garifallou, James</name>
      </author>
      <author>
        <name>Guettouche, Toumy</name>
      </author>
      <author>
        <name>Cao, Hongzhi</name>
      </author>
      <author>
        <name>Guan, Weihua</name>
      </author>
      <author>
        <name>Himes, Aubree</name>
      </author>
      <author>
        <name>van Houten, Jacob</name>
      </author>
      <author>
        <name>Pasquier, Andrew</name>
      </author>
      <author>
        <name>Yu, Reina</name>
      </author>
      <author>
        <name>Carrigan, Elena</name>
      </author>
      <author>
        <name>Miller, Michael B</name>
      </author>
      <author>
        <name>Schladt, David</name>
      </author>
      <author>
        <name>Akdere, Abdullah</name>
      </author>
      <author>
        <name>Gonzalez, Ana</name>
      </author>
      <author>
        <name>Llyod, Kelsey M</name>
      </author>
      <author>
        <name>McGinn, Daniel</name>
      </author>
      <author>
        <name>Gangasani, Abhinav</name>
      </author>
      <author>
        <name>Michaud, Zach</name>
      </author>
      <author>
        <name>Colasacco, Abigail</name>
      </author>
      <author>
        <name>Snyder, James</name>
      </author>
      <author>
        <name>Thomas, Kelly</name>
      </author>
      <author>
        <name>Wang, Tiancheng</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Alzahrani, Alhusain J</name>
      </author>
      <author>
        <name>Al-Ali, Amein K</name>
      </author>
      <author>
        <name>Al-Muhanna, Fahad A</name>
      </author>
      <author>
        <name>Al-Rubaish, Abdullah M</name>
      </author>
      <author>
        <name>Al-Mueilo, Samir</name>
      </author>
      <author>
        <name>Monos, Dimitri S</name>
      </author>
      <author>
        <name>Murphy, Barbara</name>
      </author>
      <author>
        <name>Olthoff, Kim M</name>
      </author>
      <author>
        <name>Wijmenga, Cisca</name>
      </author>
      <author>
        <name>Webster, Teresa</name>
      </author>
      <author>
        <name>Kamoun, Malek</name>
      </author>
      <author>
        <name>Balasubramanian, Suganthi</name>
      </author>
      <author>
        <name>Lanktree, Matthew B</name>
      </author>
      <author>
        <name>Oetting, William S</name>
      </author>
      <author>
        <name>Garcia-Pavia, Pablo</name>
      </author>
      <author>
        <name>MacArthur, Daniel G</name>
      </author>
      <author>
        <name>de Bakker, Paul IW</name>
      </author>
      <author>
        <name>Hakonarson, Hakon</name>
      </author>
      <author>
        <name>Birdwell, Kelly A</name>
      </author>
      <author>
        <name>Jacobson, Pamala A</name>
      </author>
      <author>
        <name>Ritchie, Marylyn D</name>
      </author>
      <author>
        <name>Asselbergs, Folkert W</name>
      </author>
      <author>
        <name>Israni, Ajay K</name>
      </author>
      <author>
        <name>Shaked, Abraham</name>
      </author>
      <author>
        <name>Keating, Brendan J</name>
      </author>
    </item>
    <item>
      <title>Proteomic Profiles in Acute Respiratory Distress Syndrome Differentiates Survivors from Non-Survivors</title>
      <link>https://escholarship.org/uc/item/5mw8f0cd</link>
      <description>Acute Respiratory Distress Syndrome (ARDS) continues to have a high mortality. Currently, there are no biomarkers that provide reliable prognostic information to guide clinical management or stratify risk among clinical trial participants. The objective of this study was to probe the bronchoalveolar lavage fluid (BALF) proteome to identify proteins that differentiate survivors from non-survivors of ARDS. Patients were divided into early-phase (1 to 7 days) and late-phase (8 to 35 days) groups based on time after initiation of mechanical ventilation for ARDS (Day 1). Isobaric tags for absolute and relative quantitation (iTRAQ) with LC MS/MS was performed on pooled BALF enriched for medium and low abundance proteins from early-phase survivors (n = 7), early-phase non-survivors (n = 8), and late-phase survivors (n = 7). Of the 724 proteins identified at a global false discovery rate of 1%, quantitative information was available for 499. In early-phase ARDS, proteins more abundant...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5mw8f0cd</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Bhargava, Maneesh</name>
      </author>
      <author>
        <name>Becker, Trisha L</name>
      </author>
      <author>
        <name>Viken, Kevin J</name>
      </author>
      <author>
        <name>Jagtap, Pratik D</name>
      </author>
      <author>
        <name>Dey, Sanjoy</name>
      </author>
      <author>
        <name>Steinbach, Michael S</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Kumar, Vipin</name>
      </author>
      <author>
        <name>Bitterman, Peter B</name>
      </author>
      <author>
        <name>Ingbar, David H</name>
      </author>
      <author>
        <name>Wendt, Christine H</name>
      </author>
    </item>
    <item>
      <title>Fast and Accurate Genome‐Wide Association Test of Multiple Quantitative Traits</title>
      <link>https://escholarship.org/uc/item/3st2q7fx</link>
      <description>Multiple correlated traits are often collected in genetic studies. By jointly analyzing multiple traits, we can increase power by aggregating multiple weak effects and reveal additional insights into the genetic architecture of complex human diseases. In this article, we propose a multivariate linear regression-based method to test the joint association of multiple quantitative traits. It is flexible to accommodate any covariates, has very accurate control of type I errors, and offers very competitive performance. We also discuss fast and accurate significance &lt;i&gt;p&lt;/i&gt; value computation especially for genome-wide association studies with small-to-medium sample sizes. We demonstrate through extensive numerical studies that the proposed method has competitive performance. Its usefulness is further illustrated with application to genome-wide association analysis of diabetes-related traits in the Atherosclerosis Risk in Communities (ARIC) study. We found some very interesting associations...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3st2q7fx</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Pankow, James S</name>
      </author>
    </item>
    <item>
      <title>Differentially Expressed Gene Transcripts Using RNA Sequencing from the Blood of Immunosuppressed Kidney Allograft Recipients</title>
      <link>https://escholarship.org/uc/item/3rt708qr</link>
      <description>We performed RNA sequencing (RNAseq) on peripheral blood mononuclear cells (PBMCs) to identify differentially expressed gene transcripts (DEGs) after kidney transplantation and after the start of immunosuppressive drugs. RNAseq is superior to microarray to determine DEGs because it's not limited to available probes, has increased sensitivity, and detects alternative and previously unknown transcripts. DEGs were determined in 32 adult kidney recipients, without clinical acute rejection (AR), treated with antibody induction, calcineurin inhibitor, mycophenolate, with and without steroids. Blood was obtained pre-transplant (baseline), week 1, months 3 and 6 post-transplant. PBMCs were isolated, RNA extracted and gene expression measured using RNAseq. Principal components (PCs) were computed using a surrogate variable approach. DEGs post-transplant were identified by controlling false discovery rate (FDR) at &amp;lt; 0.01 with at least a 2 fold change in expression from pre-transplant....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3rt708qr</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Dorr, Casey</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Guan, Weihua</name>
      </author>
      <author>
        <name>Muthusamy, Amutha</name>
      </author>
      <author>
        <name>Sanghavi, Kinjal</name>
      </author>
      <author>
        <name>Schladt, David P</name>
      </author>
      <author>
        <name>Maltzman, Jonathan S</name>
      </author>
      <author>
        <name>Scherer, Steven E</name>
      </author>
      <author>
        <name>Brott, Marcia J</name>
      </author>
      <author>
        <name>Matas, Arthur J</name>
      </author>
      <author>
        <name>Jacobson, Pamala A</name>
      </author>
      <author>
        <name>Oetting, William S</name>
      </author>
      <author>
        <name>Israni, Ajay K</name>
      </author>
    </item>
    <item>
      <title>A general statistic to test an optimally weighted combination of common and/or rare variants</title>
      <link>https://escholarship.org/uc/item/3rq6r6mb</link>
      <description>Both genome-wide association study and next-generation sequencing data analyses are widely employed to identify disease susceptible common and/or rare genetic variants. Rare variants generally have large effects though they are hard to detect due to their low frequencies. Currently, many existing statistical methods for rare variants association studies employ a weighted combination scheme, which usually puts subjective weights or suboptimal weights based on some adhoc assumptions (e.g., ignoring dependence between rare variants). In this study, we analytically derived optimal weights for both common and rare variants and proposed a general and novel approach to test association between an optimally weighted combination of variants (G-TOW) in a gene or pathway for a continuous or dichotomous trait while easily adjusting for covariates. Results of the simulation studies show that G-TOW has properly controlled type I error rates and it is the most powerful test among the methods...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3rq6r6mb</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Zhang, Jianjun</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Sha, Qiuying</name>
      </author>
      <author>
        <name>Zhang, Shuanglin</name>
      </author>
      <author>
        <name>Wang, Xuexia</name>
      </author>
    </item>
    <item>
      <title>Higher number of tacrolimus dose adjustments in kidney transplant recipients who are extensive and intermediate CYP3A5 metabolizers</title>
      <link>https://escholarship.org/uc/item/3np5m057</link>
      <description>Kidney transplant recipients carrying the CYP3A5*1 allele have lower tacrolimus troughs, and higher dose requirements compared to those with the CYP3A5*3/*3 genotype. However, data on the effect of CYP3A5 alleles on post-transplant tacrolimus management are lacking. The effect of CYP3A5 metabolism phenotypes on the number of tacrolimus dose adjustments and troughs in the first 6 months post-transplant was evaluated in 78 recipients (64% Caucasians). Time to first therapeutic concentration, percentage of time in therapeutic range (TTR), and estimated glomerular filtration rate (eGFR) were also evaluated. Fifty-five kidney transplant recipients were CYP3A5 poor metabolizers (PM), 17 were intermediate metabolizers (IM), and 6 were extensive metabolizers (EM). Compared to PMs, EMs/IMs had significantly more dose adjustments (6.1&amp;nbsp;vs. 8.1, p&amp;nbsp;=&amp;nbsp;.015). Overall, 33.82% of trough measurements resulted in a dose change. There was no difference in the number of tacrolimus trough...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3np5m057</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Reininger, Kevin A</name>
      </author>
      <author>
        <name>Onyeaghala, Guillaume</name>
      </author>
      <author>
        <name>Anderson‐Haag, Teresa</name>
      </author>
      <author>
        <name>Schladt, David S</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Guan, Weihua</name>
      </author>
      <author>
        <name>Dorr, Casey R</name>
      </author>
      <author>
        <name>Remmel, Rory P</name>
      </author>
      <author>
        <name>Mannon, Roslyn</name>
      </author>
      <author>
        <name>Matas, Arthur J</name>
      </author>
      <author>
        <name>Oetting, William S</name>
      </author>
      <author>
        <name>Stahler, Paul</name>
      </author>
      <author>
        <name>Israni, Ajay K</name>
      </author>
      <author>
        <name>Jacobson, Pamala A</name>
      </author>
    </item>
    <item>
      <title>Pharmacogenomics in kidney transplant recipients and potential for integration into practice</title>
      <link>https://escholarship.org/uc/item/3cr582cq</link>
      <description>WHAT IS KNOWN AND OBJECTIVE: Pharmacogenomic biomarkers are now used in many clinical care settings and represent one of the successes of precision medicine. Genetic variants are associated with pharmacokinetic and pharmacodynamic changes leading to medication adverse effects and changes in clinical response. Actionable pharmacogenomic variants are common in transplant recipients and have implications for medications used in transplant, but yet are not broadly incorporated into practice.
METHODS: From the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group guidelines, and PharmGKB databases, 12 pharmacogenomic genes with 30 variants were selected and used to create diplotypes and actionable pharmacogenomic phenotypes. A total of 853 kidney allograft recipients who had genomic information available from a genome-wide association study were included.
RESULTS: Each recipient had at least one actionable pharmacogenomic diplotype/phenotype,...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3cr582cq</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Nguyen, Tam T</name>
      </author>
      <author>
        <name>Pearson, Rachael A</name>
      </author>
      <author>
        <name>Mohamed, Moataz E</name>
      </author>
      <author>
        <name>Schladt, David P</name>
      </author>
      <author>
        <name>Berglund, Danielle</name>
      </author>
      <author>
        <name>Rivers, Zachary</name>
      </author>
      <author>
        <name>Skaar, Debra J</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>Guan, Weihua</name>
      </author>
      <author>
        <name>van Setten, Jessica</name>
      </author>
      <author>
        <name>Keating, Brendan J</name>
      </author>
      <author>
        <name>Dorr, Casey</name>
      </author>
      <author>
        <name>Remmel, Rory P</name>
      </author>
      <author>
        <name>Matas, Arthur J</name>
      </author>
      <author>
        <name>Mannon, Roslyn B</name>
      </author>
      <author>
        <name>Israni, Ajay K</name>
      </author>
      <author>
        <name>Oetting, William S</name>
      </author>
      <author>
        <name>Jacobson, Pamala A</name>
      </author>
    </item>
    <item>
      <title>Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups</title>
      <link>https://escholarship.org/uc/item/2rq58875</link>
      <description>Tacrolimus trough and dose requirements vary dramatically between individuals of European and African American ancestry. These differences are less well described in other populations. We conducted an observational, prospective, multicenter study from which 2595 kidney transplant recipients of European, African, Native American, and Asian ancestry were studied for tacrolimus trough, doses, and genetic determinants of metabolism. We studied the well-known variants and conducted a CYP3A4/5 gene-wide analysis to identify new variants. Daily doses, and dose-normalized troughs were significantly different between the four groups (P&amp;nbsp;&amp;lt;&amp;nbsp;.001). CYP3A5*3 (rs776746) was associated with higher dose-normalized tacrolimus troughs in all groups but occurred at different allele frequencies and had differing effect sizes. The CYP3A5*6 (rs10264272) and *7 (rs413003343) variants were only present in African Americans. CYP3A4*22 (rs35599367) was not found in any of the Asian ancestry...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2rq58875</guid>
      <pubDate>Sat, 11 May 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Mohamed, Moataz E</name>
      </author>
      <author>
        <name>Schladt, David P</name>
      </author>
      <author>
        <name>Guan, Weihua</name>
      </author>
      <author>
        <name>Wu, Baolin</name>
        <uri>https://orcid.org/0000-0001-6676-0422</uri>
      </author>
      <author>
        <name>van Setten, Jessica</name>
      </author>
      <author>
        <name>Keating, Brendan J</name>
      </author>
      <author>
        <name>Iklé, David</name>
      </author>
      <author>
        <name>Remmel, Rory P</name>
      </author>
      <author>
        <name>Dorr, Casey R</name>
      </author>
      <author>
        <name>Mannon, Roslyn B</name>
      </author>
      <author>
        <name>Matas, Arthur J</name>
      </author>
      <author>
        <name>Israni, Ajay K</name>
      </author>
      <author>
        <name>Oetting, William S</name>
      </author>
      <author>
        <name>Jacobson, Pamala A</name>
      </author>
      <author>
        <name>Investigators, for the DeKAF Genomics and GEN03</name>
      </author>
    </item>
    <item>
      <title>From formative design to service-ready therapeutic: A pragmatic approach to designing digital mental health interventions across domains</title>
      <link>https://escholarship.org/uc/item/5vd3n2cj</link>
      <description>As digital mental health interventions (DMHIs) proliferate, there is a growing need to understand the complexities of moving these tools from concept and design to service-ready products. We highlight five case studies from a center that specializes in the design and evaluation of digital mental health interventions to illustrate pragmatic approaches to the development of digital mental health interventions, and to make transparent some of the key decision points researchers encounter along the design-to-product pipeline. Case studies cover different key points in the design process and focus on partnership building, understanding the problem or opportunity, prototyping the product or service, and testing the product or service. We illustrate lessons learned and offer a series of questions researchers can use to navigate key decision points in the digital mental health intervention (DMHI) development process.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5vd3n2cj</guid>
      <pubDate>Thu, 25 Apr 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Meyerhoff, Jonah</name>
      </author>
      <author>
        <name>Kornfield, Rachel</name>
      </author>
      <author>
        <name>Lattie, Emily G</name>
      </author>
      <author>
        <name>Knapp, Ashley A</name>
      </author>
      <author>
        <name>Kruzan, Kaylee P</name>
      </author>
      <author>
        <name>Jacobs, Maia</name>
      </author>
      <author>
        <name>Stamatis, Caitlin A</name>
      </author>
      <author>
        <name>Taple, Bayley J</name>
      </author>
      <author>
        <name>Beltzer, Miranda L</name>
      </author>
      <author>
        <name>Berry, Andrew BL</name>
      </author>
      <author>
        <name>Reddy, Madhu</name>
      </author>
      <author>
        <name>Mohr, David C</name>
      </author>
      <author>
        <name>Graham, Andrea K</name>
      </author>
    </item>
    <item>
      <title>Bridging HCI and Implementation Science for Innovation Adoption and Public Health Impact</title>
      <link>https://escholarship.org/uc/item/1r44d1gz</link>
      <description>Human computer interaction (HCI) and implementation science (IS) each have been applied to improve the adoption and delivery of innovative health interventions, and the two fields have complementary goals, foci, and methods. While the IS community increasingly draws on methods from HCI, there are many unrealized opportunities for HCI to draw from IS and to catalyze bidirectional collaborations. This workshop will explore similarities and differences between fields, with a goal of articulating a research agenda at their intersection.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1r44d1gz</guid>
      <pubDate>Wed, 17 Apr 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Lyon, Aaron</name>
      </author>
      <author>
        <name>Munson, Sean A</name>
      </author>
      <author>
        <name>Reddy, Madhu</name>
      </author>
      <author>
        <name>Schueller, Stephen M</name>
        <uri>https://orcid.org/0000-0002-1003-0399</uri>
      </author>
      <author>
        <name>Agapie, Elena</name>
      </author>
      <author>
        <name>Yarosh, Svetlana</name>
      </author>
      <author>
        <name>Dopp, Alex</name>
      </author>
      <author>
        <name>von Thiele Schwarz, Ulrica</name>
      </author>
      <author>
        <name>Doherty, Gavin</name>
      </author>
      <author>
        <name>Graham, Andrea K</name>
      </author>
      <author>
        <name>Kruzan, Kaylee Payne</name>
      </author>
      <author>
        <name>Kornfield, Rachel</name>
      </author>
    </item>
    <item>
      <title>How does medical scribes’ work inform development of speech-based clinical documentation technologies? A systematic review</title>
      <link>https://escholarship.org/uc/item/1992n6p9</link>
      <description>OBJECTIVE: Use of medical scribes reduces clinician burnout by sharing the burden of clinical documentation. However, medical scribes are cost-prohibitive for most settings, prompting a growing interest in developing ambient, speech-based technologies capable of automatically generating clinical documentation based on patient-provider conversation. Through a systematic review, we aimed to develop a thorough understanding of the work performed by medical scribes in order to inform the design of such technologies.
MATERIALS AND METHODS: Relevant articles retrieved by searching in multiple literature databases. We conducted the screening process following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) in guidelines, and then analyzed the data using qualitative methods to identify recurring themes.
RESULTS: The literature search returned 854 results, 65 of which met the inclusion criteria. We found that there is significant variation in scribe expectations...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1992n6p9</guid>
      <pubDate>Sun, 7 Apr 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Tran, Brian D</name>
      </author>
      <author>
        <name>Chen, Yunan</name>
      </author>
      <author>
        <name>Liu, Songzi</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
    </item>
    <item>
      <title>Applying a family stress model to understand U.S. families’ patterns of stress, media use, and child behavior during the COVID-19 pandemic</title>
      <link>https://escholarship.org/uc/item/5m1324cr</link>
      <description>The COVID-19 pandemic has greatly altered family life, and research among adults and families is finding increases in financial stress, mental health problems, screen time, parental conflict, and child behavior problems. Given these patterns, we sought to replicate these findings with a younger and largely non-white sample and consider how these constructs might relate to each other by using the Family Stress Model. From surveys of 247 predominately Latine mothers and fathers of children under 4 years in the U.S., we found that financial strain was related to children's media exposure and use, largely through impacts on parents' mental health and coparenting relationship. Interestingly, only use of television in the background and during mealtimes were associated with increases in children's behavior problems. Such findings better capture how stress may operate in a family system and offer a way to counsel parents about healthier media habits for children.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5m1324cr</guid>
      <pubDate>Fri, 29 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Reich, Stephanie M</name>
        <uri>https://orcid.org/0000-0002-8799-5236</uri>
      </author>
      <author>
        <name>Liu, Yujia</name>
      </author>
      <author>
        <name>Tulagan, Nestor</name>
      </author>
      <author>
        <name>Martin, Esmeralda</name>
      </author>
      <author>
        <name>Dahlin, Melissa</name>
      </author>
      <author>
        <name>Cabrera, Natasha</name>
      </author>
    </item>
    <item>
      <title>Mindfulness video game improves connectivity of the fronto-parietal attentional network in adolescents: A multi-modal imaging study</title>
      <link>https://escholarship.org/uc/item/0dz2m03p</link>
      <description>Mindfulness training has been shown to improve attention and change the underlying brain substrates in adults. Most mindfulness training programs involve a myriad of techniques, and it is difficult to attribute changes to any particular aspect of the program. Here, we created a video game, Tenacity, which models a specific mindfulness technique – focused attention on one’s breathing – and assessed its potential to train an attentional network in adolescents. A combined analysis of resting state functional connectivity (rs-FC) and diffusion tensor imaging (DTI) yielded convergent results – change in communication within the left fronto-parietal network after two weeks of playing Tenacity compared to a control game. Rs-FC analysis showed greater connectivity between left dorsolateral prefrontal cortex (dlPFC) and left inferior parietal cortex (IPC) in the Tenacity group. Importantly, changes in left dlPFC – IPC rs-FC and changes in structural connectivity of the white matter tract...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0dz2m03p</guid>
      <pubDate>Sat, 23 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Patsenko, Elena G</name>
      </author>
      <author>
        <name>Adluru, Nagesh</name>
      </author>
      <author>
        <name>Birn, Rasmus M</name>
      </author>
      <author>
        <name>Stodola, Diane E</name>
      </author>
      <author>
        <name>Kral, Tammi RA</name>
      </author>
      <author>
        <name>Farajian, Reza</name>
      </author>
      <author>
        <name>Flook, Lisa</name>
      </author>
      <author>
        <name>Burghy, Cory A</name>
      </author>
      <author>
        <name>Steinkuehler, Constance</name>
      </author>
      <author>
        <name>Davidson, Richard J</name>
      </author>
    </item>
    <item>
      <title>Neural correlates of video game empathy training in adolescents: a randomized trial</title>
      <link>https://escholarship.org/uc/item/92m1j6mj</link>
      <description>The ability to understand emotional experiences of others, empathy, is a valuable skill for effective social interactions. Various types of training increase empathy in adolescents, but their impact on brain circuits underlying empathy has not been examined. Video games provide a unique medium familiar and engaging to adolescents and can be used to deliver training at scale. We developed an empathy training video game, Crystals of Kaydor (Crystals), and investigated whether playing Crystals increases empathic accuracy (EA) and related brain activation in adolescents (N = 74; 27 female; mean age(sd) = 12.8(0.7) years; age range 11–14 years). Participants completed a resting state functional MRI (rs-fMRI) scan and an EA task during an fMRI scan before and after 2 weeks of daily gameplay with either the empathy training game, Crystals (N = 34), or the commercial video game Bastion (N = 40), an active control condition. There were no group differences in EA improvement following gameplay,...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/92m1j6mj</guid>
      <pubDate>Fri, 22 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Kral, Tammi RA</name>
      </author>
      <author>
        <name>Stodola, Diane E</name>
      </author>
      <author>
        <name>Birn, Rasmus M</name>
      </author>
      <author>
        <name>Mumford, Jeanette A</name>
      </author>
      <author>
        <name>Solis, Enrique</name>
      </author>
      <author>
        <name>Flook, Lisa</name>
      </author>
      <author>
        <name>Patsenko, Elena G</name>
      </author>
      <author>
        <name>Anderson, Craig G</name>
      </author>
      <author>
        <name>Steinkuehler, Constance</name>
      </author>
      <author>
        <name>Davidson, Richard J</name>
      </author>
    </item>
    <item>
      <title>Understanding UX Better: A New Technique to Go beyond Emotion Assessment</title>
      <link>https://escholarship.org/uc/item/7tb1n49r</link>
      <description>User experience (UX) is a quality aspect that considers the emotions evoked by the system, extending the usability concept beyond effectiveness, efficiency, and satisfaction. Practitioners and researchers are aware of the importance of evaluating UX. Thus, UX evaluation is a growing field with diverse approaches. Despite various approaches, most of them produce a general indication of the experience as a result and do not seek to capture the problem that gave rise to the bad UX. This information makes it difficult to obtain relevant results to improve the application, making it challenging to identify what caused a negative user experience. To address this gap, we developed a UX evaluation technique called UX-Tips. This paper presents UX-Tips and reports two empirical studies performed in an academic and an industrial setting to evaluate it. Our results show that UX-Tips had good performance in terms of efficiency and effectiveness, making it possible to identify the causes that...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7tb1n49r</guid>
      <pubDate>Fri, 22 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Marques, Leonardo</name>
      </author>
      <author>
        <name>Matsubara, Patrícia Gomes</name>
      </author>
      <author>
        <name>Nakamura, Walter Takashi</name>
      </author>
      <author>
        <name>Ferreira, Bruna Moraes</name>
      </author>
      <author>
        <name>Wiese, Igor Scaliante</name>
      </author>
      <author>
        <name>Gadelha, Bruno Freitas</name>
      </author>
      <author>
        <name>Zaina, Luciana Martinez</name>
      </author>
      <author>
        <name>Redmiles, David</name>
        <uri>https://orcid.org/0000-0002-1370-7123</uri>
      </author>
      <author>
        <name>Conte, Tayana Uchôa</name>
      </author>
    </item>
    <item>
      <title>Child-Centered Design in the Digital World: Investigating the Implications of the Age-Appropriate Design Code for Interactive Digital Media</title>
      <link>https://escholarship.org/uc/item/7sv903th</link>
      <description>In this paper, we conduct a content analysis to investigate the implications of the "Age-Appropriate Design Code" for the design of interactive digital media children are likely to use. The "Age-Appropriate Design Code" policy framework, implemented in the United Kingdom in 2021 with a modified version later signed into law in California in 2022, shifts the focus beyond just the protection of children’s data to a broader focus on how the interaction with digital technologies might affect or even harm children. Our content analysis of both the UK and California codes identifies a number of design considerations framed around four main categories namely design values, communication of information, interactions with technology, and data management. While recognizing the robustness of the Age-Appropriate Design Codes, we also identify certain uncertainties and challenges in implementing guidelines in the context of interactive digital media. Our findings contribute to the ongoing...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7sv903th</guid>
      <pubDate>Wed, 20 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Grace, Thomas D</name>
      </author>
      <author>
        <name>Abel, Christie</name>
      </author>
      <author>
        <name>Salen, Katie</name>
        <uri>https://orcid.org/0000-0002-8902-8282</uri>
      </author>
    </item>
    <item>
      <title>Unveiling Elite Developers’ Activities in Open Source Projects</title>
      <link>https://escholarship.org/uc/item/124071jg</link>
      <description>Open source developers, particularly the elite developers who own the administrative privileges for a project, maintain a diverse portfolio of contributing activities. They not only commit source code but also exert significant efforts on other communicative, organizational, and supportive activities. However, almost all prior research focuses on specific activities and fails to analyze elite developers' activities in a comprehensive way. To bridge this gap, we conduct an empirical study with fine-grained event data from 20 large open source projects hosted on GITHUB. We investigate elite developers' contributing activities and their impacts on project outcomes. Our analyses reveal three key findings: (1) elite developers participate in a variety of activities, of which technical contributions (e.g., coding) only account for a small proportion; (2) as the project grows, elite developers tend to put more effort into supportive and communicative activities and less effort into coding;...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/124071jg</guid>
      <pubDate>Mon, 18 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Wang, Zhendong</name>
      </author>
      <author>
        <name>Feng, Yang</name>
      </author>
      <author>
        <name>Wang, Yi</name>
      </author>
      <author>
        <name>Jones, James A</name>
      </author>
      <author>
        <name>Redmiles, David</name>
      </author>
    </item>
    <item>
      <title>Moving Forward &lt;i&gt;Connections to Practice and Design&lt;/i&gt;</title>
      <link>https://escholarship.org/uc/item/0kh59408</link>
      <description>Moving Forward &lt;i&gt;Connections to Practice and Design&lt;/i&gt;</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0kh59408</guid>
      <pubDate>Wed, 13 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Ito, Mizuko</name>
      </author>
      <author>
        <name>Martin, Crystle</name>
      </author>
      <author>
        <name>Pfister, Rachel Cody</name>
      </author>
      <author>
        <name>Rafalow, Matthew H</name>
      </author>
      <author>
        <name>Salen, Katie</name>
        <uri>https://orcid.org/0000-0002-8902-8282</uri>
      </author>
      <author>
        <name>Wortman, Amanda</name>
      </author>
    </item>
    <item>
      <title>The carbon emissions of writing and illustrating are lower for AI than for humans</title>
      <link>https://escholarship.org/uc/item/17t8n0gr</link>
      <description>As AI systems proliferate, their greenhouse gas emissions are an increasingly important concern for human societies. In this article, we present a comparative analysis of the carbon emissions associated with AI systems (ChatGPT, BLOOM, DALL-E2, Midjourney) and human individuals performing equivalent writing and illustrating tasks. Our findings reveal that AI systems emit between 130 and 1500 times less CO2e per page of text generated compared to human writers, while AI illustration systems emit between 310 and 2900 times less CO2e per image than their human counterparts. Emissions analyses do not account for social impacts such as professional displacement, legality, and rebound effects. In addition, AI is not a substitute for all human tasks. Nevertheless, at present, the use of AI holds the potential to carry out several major activities at much lower emission levels than can humans.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/17t8n0gr</guid>
      <pubDate>Sat, 2 Mar 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Tomlinson, Bill</name>
        <uri>https://orcid.org/0000-0002-8386-4730</uri>
      </author>
      <author>
        <name>Black, Rebecca W</name>
        <uri>https://orcid.org/0000-0003-2412-6217</uri>
      </author>
      <author>
        <name>Patterson, Donald J</name>
        <uri>https://orcid.org/0000-0001-8525-0495</uri>
      </author>
      <author>
        <name>Torrance, Andrew W</name>
      </author>
    </item>
    <item>
      <title>Variability in the Integration of Peers in a Multi-site Digital Mental Health Innovation Project</title>
      <link>https://escholarship.org/uc/item/2vr8754c</link>
      <description>Peer support specialists (“peers”) who have the lived experience of, and are in recovery from, mental health challenges are increasingly being integrated into mental health care as a reimbursable service across the US. This study describes the ways peers were integrated into Help@Hand, a multi-site innovation project that engaged peers throughout efforts to develop and offer digital mental health interventions across counties/cities (“sites”) in California. Using a mixed methods design, we collected quantitative data via quarterly online surveys, and qualitative data via semi-annual semi-structured phone interviews with key informants from Help@Hand sites. Quantitative data were summarized as descriptive findings and qualitative data from interviews were analyzed using rapid qualitative analysis methods. In the final analytic phase, interview quotes were used to illustrate the complex realities underlying quantitative responses. 117 quarterly surveys and 46 semi-annual interviews...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2vr8754c</guid>
      <pubDate>Tue, 20 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Cha, Biblia S</name>
      </author>
      <author>
        <name>Borghouts, Judith</name>
      </author>
      <author>
        <name>Eikey, Elizabeth</name>
        <uri>https://orcid.org/0000-0002-3099-8081</uri>
      </author>
      <author>
        <name>Mukamel, Dana B</name>
        <uri>https://orcid.org/0000-0003-4147-5785</uri>
      </author>
      <author>
        <name>Schueller, Stephen M</name>
        <uri>https://orcid.org/0000-0002-1003-0399</uri>
      </author>
      <author>
        <name>Sorkin, Dara H</name>
        <uri>https://orcid.org/0000-0003-0742-9240</uri>
      </author>
      <author>
        <name>Stadnick, Nicole A</name>
        <uri>https://orcid.org/0000-0001-6520-2920</uri>
      </author>
      <author>
        <name>Zhao, Xin</name>
      </author>
      <author>
        <name>Zheng, Kai</name>
        <uri>https://orcid.org/0000-0003-4121-4948</uri>
      </author>
      <author>
        <name>Schneider, Margaret L</name>
        <uri>https://orcid.org/0000-0002-8314-0732</uri>
      </author>
    </item>
    <item>
      <title>“We hear everyday, ‘this isn’t me.’” Navigating tensions and opportunities to translate interests toward entrepreneurial making</title>
      <link>https://escholarship.org/uc/item/871801q2</link>
      <description>Out-of-school time (OST) makerspaces are spaces for youth to engage in exploratory practices and deepen STEM interests in personally meaningful ways. Many youth—especially teens—additionally benefit from supportive relationships (e.g., caring adult mentors, peer mentors) in these spaces to help them uncover their interests and translate them into long-term trajectories of maker practice. Using a connected learning lens, this paper focuses on supportive adult relationships at a high school OST program (Sunrise of Philadelphia), and the ways in which practices around interest identification and development within its makerspace entrepreneurship program meaningfully impacted learning trajectories for youth by connecting them to new STEM opportunities, knowledge, and experiences. Through an illustrative case study, we present a portrait-of-practice that shows how OST educators facilitated brokering to connect youth to resources, mentoring, materials, and new communities that transcended...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/871801q2</guid>
      <pubDate>Thu, 15 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Dahn, Maggie</name>
      </author>
      <author>
        <name>Peppler, Kylie A</name>
        <uri>https://orcid.org/0000-0002-5472-4974</uri>
      </author>
      <author>
        <name>Ito, Mizuko</name>
      </author>
    </item>
    <item>
      <title>Connected Arts Learning: Cultivating Equity Through Connected and Creative Educational Experiences</title>
      <link>https://escholarship.org/uc/item/4vz4p36v</link>
      <description>This review brings together scholarship from creative educational experiences (CEE) and connected learning to describe a connected arts learning framework, reframing arts education in the 21st century with a focus on connecting youths’ interest-driven art making to opportunities through supportive relationships. Such a framework pushes the arts education field to consider outcomes beyond artistic skill acquisition and academic achievement to include a broader range of opportunities, including those civic- and career-related; promote interest development through targeted exposure to new forms of art making; create and implement professional development and programming to emphasize networks and connections; and draw from culturally sustaining practices to bridge connections between spaces for learning. A connected learning lens applied to what we know about high quality arts education sharpens our focus on how CEE can cultivate equity and social/cultural connection for youth.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4vz4p36v</guid>
      <pubDate>Thu, 15 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Peppler, Kylie</name>
      </author>
      <author>
        <name>Dahn, Maggie</name>
      </author>
      <author>
        <name>Ito, Mizuko</name>
      </author>
    </item>
    <item>
      <title>Engineering Play: Children's software and the cultural politics of edutainment</title>
      <link>https://escholarship.org/uc/item/2bm2q55m</link>
      <description>The late 1980s saw the emergence of a new genre of instructional media, 'edutainment, which utilized the capabilities of multimedia personal computers to animate software designed to both educate and entertain young children. This paper describes the production of, marketing of and play with edutainment software as a contemporary example of long-standing tensions between the cultural categories of education and entertainment, play and learning. Like prior efforts to wed learning and play, edutainment was founded on the ideal of broadening access to academic learning. Yet, as it became a mainstream commercial enterprise, it was increasingly targeted towards accelerating the achievement of successful children. After first describing the industry and marketing context of edutainment, this paper describes cases of play with edutainment software in an after-school computer club. The analysis utilizes the concepts of "multimedia genre and "participation genre to read across sites of...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2bm2q55m</guid>
      <pubDate>Thu, 15 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Ito, Mizuko</name>
      </author>
    </item>
    <item>
      <title>Principios, aplicaciones y retos del aprendizaje conectado</title>
      <link>https://escholarship.org/uc/item/1z77c4nm</link>
      <description>Por aprendizaje conectado se entiende aquella actividad, práctica o experiencia que vincula los intereses de los aprendices con oportunidades académicas, profesionales y cívicas, a través del apoyo y promoción ofrecida por otros y otras. El propósito fundamental de este artículo consiste en situar dicha aproximación, a la vez teórica y aplicada. Para ello, se describe su origen, los principios o ideas fuerza que subyacen a dicha teoría, así como las condiciones sociales y materiales necesarias para implementar prácticas educativas conectadas desde la perspectiva de la equidad relacional. Se describen algunos ejemplos de aprendizaje conectado para, finalmente, señalar lo que consideramos son algunas de las limitaciones de dicho enfoque, así como retos para su desarrollo e implementación.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1z77c4nm</guid>
      <pubDate>Thu, 15 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Esteban-Guitart, Moises</name>
      </author>
      <author>
        <name>DiGiacomo, Daniela</name>
      </author>
      <author>
        <name>Penuel, William</name>
      </author>
      <author>
        <name>Ito, Mizuko</name>
      </author>
    </item>
    <item>
      <title>Online Affinity Networks as Contexts for Connected Learning</title>
      <link>https://escholarship.org/uc/item/0zg5p7m5</link>
      <description>This chapter describes the ways in which online affinity networks motivate learning and support interest development. It builds on the model of "connected learning" that posits that learning is most resilient and meaningful when it is tied to social relationships and cultural identities, and spans in-school and out-of-school settings. The analysis draws from ethnographic case studies of youth-centered networks focused on fanfiction, knitting, professional wrestling, anime video remixers, Bollywood dance, YouTube vloggers, and communities surrounding two games, Little Big Planet 2 and StarCraft II. Factors that draw young people to online spaces to pursue their interests are diverse. For some, it is to find a safe space for a stigmatized interest. For others, it is because of an attraction to a narrow niche, leveling up, or technical specialization that is only accessible online. In all cases, however, high functioning online affinity networks are characterized by a strong set...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0zg5p7m5</guid>
      <pubDate>Thu, 15 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Ito, Mizuko</name>
      </author>
      <author>
        <name>Martin, Crystle</name>
      </author>
      <author>
        <name>Rafalow, Matthew</name>
      </author>
      <author>
        <name>Tekinbas, Katie Salen</name>
      </author>
      <author>
        <name>Wortman, Amanda</name>
      </author>
      <author>
        <name>Pfister, Rachel Cody</name>
      </author>
    </item>
    <item>
      <title>Co-Creation in Fully Remote Software Teams</title>
      <link>https://escholarship.org/uc/item/08q1788c</link>
      <description>Co-Creation in Fully Remote Software Teams</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/08q1788c</guid>
      <pubDate>Thu, 15 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Jackson, Victoria</name>
        <uri>https://orcid.org/0000-0002-6326-931X</uri>
      </author>
      <author>
        <name>Prikladnicki, Rafael</name>
        <uri>https://orcid.org/0000-0003-3351-4916</uri>
      </author>
      <author>
        <name>van der Hoek, Andre</name>
        <uri>https://orcid.org/0000-0001-7917-932X</uri>
      </author>
    </item>
    <item>
      <title>A 3/2-Approximation Algorithm for Augmenting the Edge-Connectivity of a Graph from 1 to 2 Using a Subset of a Given Edge Set</title>
      <link>https://escholarship.org/uc/item/8hk01207</link>
      <description>We consider the following problem: given a connected graph G = (V, ε E) and an additional edge set E, find a minimum size subset of edges F ⊆ E such that (V, ε ∪ F) is 2-edge connected. This problem is NP-hard. For a long time, 2 was the best approximation ratio known. Recently, Nagamochi reported a (1.875 + ε)-approximation algorithm. We give a new algorithm with a better approximation ratio of 3/2 and a practical running time.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8hk01207</guid>
      <pubDate>Wed, 7 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Even, Guy</name>
      </author>
      <author>
        <name>Feldman, Julian</name>
      </author>
      <author>
        <name>Kortsarz, Guy</name>
      </author>
      <author>
        <name>Nutov, Zeev</name>
      </author>
    </item>
    <item>
      <title>Translator writing systems</title>
      <link>https://escholarship.org/uc/item/7p07s766</link>
      <description>A critical review of recent efforts to automate the writing of translators of programming languages is presented. The formal study of syntax and its application to translator writing are discussed in Section II. Various approaches to automating the postsyntactic (semantic) aspects of translator writing are discussed in Section III, and several related topics in Section IV.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7p07s766</guid>
      <pubDate>Wed, 7 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Feldman, Jerome</name>
      </author>
      <author>
        <name>Gries, David</name>
      </author>
    </item>
    <item>
      <title>TALL—a list processor for the Philco 2000 computer</title>
      <link>https://escholarship.org/uc/item/6qk36727</link>
      <description>Several of the computer languages that are oriented toward problems in symbol manipulation use a list type of memory organization.
            1
            The advantages of such a memory organization have been discussed elsewhere and will not be repeated here. The purpose of this note is to describe the method used in realizing a list language on the Philco 2000.
           

          
            Information Processing Language V (IPL-V) was chosen as the source language for the list processor for the 2000 because this language has been well documented and has been implemented on several computers.
            2
            Heretofore, IPL-V has been implemented as an interpretive system. The interpretive system has three major components: (1) a loader which translates card images into internal machine words; (2) an interpreter which decodes instructions; and (3) a set of primitive processes, the “J's,” which make up the bulk of the instruction vocabulary. The implementation...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6qk36727</guid>
      <pubDate>Wed, 7 Feb 2024 00:00:00 +0000</pubDate>
      <author>
        <name>Feldman, Julian</name>
      </author>
    </item>
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