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    <title>Recent issr_volume6 items</title>
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    <description>Recent eScholarship items from Volume VI. 1994-95 - Biotechnology Studies</description>
    <pubDate>Thu, 25 Jun 2026 07:26:33 +0000</pubDate>
    <item>
      <title>China's Rural Enterprises: Effects of Agriculture, Surplus Labor, and Human Capital</title>
      <link>https://escholarship.org/uc/item/4zc171bm</link>
      <description>&lt;p&gt;Rural industry is the most dynamic sector in China. I argue that rural industrialization is funded by agricultural accumulation, driven by surplus labor, and sustained by human capital. Rural reforms since 1978 have allowed Chinese peasants to retain a larger share of agricultural surplus to be transferred into rural industries. Rural surplus labor and shortage of farmland drive rural industrialization by the dynamic of extensive growth. Education is crucial for rural industrialization because market competition raises returns to human capital and industries need schooling more than does agriculture. 1991 data of 1,903 counties show that the top 10% of the counties produced over half of the total output by rural enterprises whereas the bottom 50% contributed little. Regression analyses confirm the above argument and find that education is the strongest predictor of rural industrial development.&lt;/p&gt;</description>
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      <pubDate>Tue, 9 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Peng, Yusheng</name>
      </author>
    </item>
    <item>
      <title>Inter-Institutional Spillover Effects in the Commercialization of Bioscience</title>
      <link>https://escholarship.org/uc/item/4d96f3xh</link>
      <description>&lt;p&gt;We examine the effects of university-based star scientists on three measures of performance for California biotechnology enterprises: the number of products in development, the number of products on the market, and changes in employment. The “star” concept which Zucker, Darby, and Brewer (1994) demonstrated was important for birth of US. biotechnology enterprises also predicts geographically localized knowledge spillovers at least for products in development. However, when we break down university stars into those who have collaborated on publications with scientists affiliated with the firm and all other university stars, there is a strong positive effect of the linked stars on all three firm-performance measures and little or no evidence of an effect from the other university stars.&lt;/p&gt;&lt;p&gt;We develop a new hypothesis of geographically localized effects of university research which is consistent with market exchange: Geographically localized effects occur for scientific discoveries...</description>
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      <pubDate>Tue, 9 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Zucker, Lynne G.</name>
      </author>
      <author>
        <name>Darby, Michael R.</name>
      </author>
      <author>
        <name>Armstrong, Jeff</name>
      </author>
    </item>
    <item>
      <title>Social Networks, Learning, and Flexibility: Sourcing Scientific Knowledge in New Biotechnology Firms</title>
      <link>https://escholarship.org/uc/item/4480h6s7</link>
      <description>&lt;p&gt;This paper examines the organizational arrangements used by New Biotechnology Firms (NBFs) to source scientific knowledge. Using data from two highly successful NBFs, the paper shows that both firms relied principally on hierarchies and networks to source scientific knowledge; market arrangements were insignificant. Most interesting, each firm had a very large, diversified set of boundary-spanning collaborative research arrangements, mostly involving university scientists. It is argued that these external research networks enabled the two firms studied to compete more successfully in a highly turbulent and highly competitive industry environment.&lt;/p&gt;</description>
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      <pubDate>Tue, 9 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Liebeskind, Julia Porter</name>
      </author>
      <author>
        <name>Oliver, Amalya Lumerman</name>
      </author>
      <author>
        <name>Zucker, Lynne G.</name>
      </author>
      <author>
        <name>Brewer, Marilynn B.</name>
      </author>
    </item>
    <item>
      <title>In Between Markets and Hierarchies - Networking Through the Life Cycle of New Biotechnology Firms</title>
      <link>https://escholarship.org/uc/item/2nw4d7c3</link>
      <description>&lt;p&gt;Resource dependence and transaction cost theories focus on organizations as mitigating their dependence on the task environment through various strategies. However, these theories have contradicting predictions as to the conditions under which network alliances are formed. New Biotechnology Firms (NBFs) provide an example of knowledge-organizations, operating under uncertainty and competitive environmental constraints, yet highly dependent on external resources. The event history analysis (EVA) of NBFs (N=554) shows that although avoidance of formation of alliances is associated with death, the formation of at least one inter-organizational alliance for each age year of the firm has an inverse U shape. The life cycle dependence argument is further supported when an analysis conducted on only self-standing NBFs shows a higher and longer dependency on external alliances. These findings suggest an integration of the two theories into a firm life cycle network theory within the...</description>
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      <pubDate>Tue, 9 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Oliver, Amalya Lumerman</name>
      </author>
    </item>
    <item>
      <title>Institutional Analyses of Organizations: Legitimate but not Institutionalized</title>
      <link>https://escholarship.org/uc/item/23z6m92c</link>
      <description>&lt;p&gt;We review institutional theory to assess the direction of theory and research on institutional structures and processes. Our primary goal is to suggest an overall frame within which a coherent and interrelated body of theory and research might develop that would address institutional processes underlying stability and change of organizational structure. We select two theoretical threads, phenomenological and neo-functional approaches to organizations, and weave these in with rational choice to develop a coherent explanation of the conditions under which similar structures diffuse across organizations facing very different environments (or have very different structures when facing the same environment). We argue that resource dependence theory already provides a parsimonious explanation of why organizational structure becomes so similar across organizations facing similar environments; institutional theory has little to add to this scenario, except perhaps for a theory of organization-level...</description>
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      <pubDate>Tue, 9 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Tolbert, Pamela S.</name>
      </author>
      <author>
        <name>Zucker, Lynne G.</name>
      </author>
    </item>
    <item>
      <title>The Organization of Biotechnology Science and Its Commercialization in Japan</title>
      <link>https://escholarship.org/uc/item/9qf459t4</link>
      <description>&lt;p&gt;The biotechnology revolution is of particular interest both for the sociology of science and for industrial organization. Indeed, the closeness of progress in the basic science to applications in industry makes it impossible to understand the development of the industry without understanding the progress of the science and linkages between the two domains. In the U.S., Zucker, Darby, and Brewer (1994) demonstrates that where and when “star” scientists at the research frontier (and, in later years, their collaborators) were actively publishing were important determinants of where and when new biotechnology enterprises (NBEs) were founded.In ongoing work extending the analysis to Japan, it is seen that while the structure of science related to the new biotechnologies is broadly similar between the United States and Japan, the organization of the biotechnology industry in the two countries is quite dissimilar. In the U.S., at least 68 percent of NBEs were new biotechnology firms...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9qf459t4</guid>
      <pubDate>Mon, 8 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Zucker, Lynne G.</name>
      </author>
      <author>
        <name>Darby, Michael R.</name>
      </author>
    </item>
    <item>
      <title>Collaboration Structure and Information Dilemmas in Biotechnology: Organizational Boundaries as Trust Production</title>
      <link>https://escholarship.org/uc/item/0gd8j9k8</link>
      <description>&lt;p&gt;Scientists who make breakthrough discoveries can receive above-normal returns to their intellectual capital, with returns depending on the degree of natural excludability, that is whether necessary techniques can be learned through written repons or instead require hands-on experience with the discovering scientists or those trained by them in their laboratory. Privatizing discoveries, then, only requires selecting trusted others as collaborators,most often scientists working in the same organization. Within organizational boundaries, incentives become aligned based on repeat and future exchange, coupled with third-party monitoring and enforcement.We find that high value intellectual capital paradoxically predicts both a larger number of collaborators and more of that network contained within the same organization. Specifically, same-organization collaboration pairs are more likely when the value of the intellectual capital is high: both are highly productive ‘star” scientists,...</description>
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      <pubDate>Mon, 8 Jul 2002 00:00:00 +0000</pubDate>
      <author>
        <name>Zucker, Lynne G.</name>
      </author>
      <author>
        <name>Brewer, Marilynn B.</name>
      </author>
      <author>
        <name>Darby, Michael R.</name>
      </author>
      <author>
        <name>Peng, Yusheng</name>
      </author>
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