Recent uci_cncm_proceedings items

Program Book - Structure, Function and Development of Neural Circuits

Thu, 18 Jan 2024 00:00:00 +0000

Program Book - Structure, Function and Development of Neural Circuits

Cell Type Organization Across the Mouse Brain

Fri, 22 Sep 2023 00:00:00 +0000

To understand the function of the brain and how its dysfunction leads to brain diseases, it is essential to uncover the cell type composition of the brain, how the cell types are connected with each other and what their roles are in circuit function. At the Allen Institute, we have built multiple technology platforms, including single-cell transcriptomics, spatial transcriptomics, single and multi-patching electrophysiology, 3D reconstruction of neuronal morphology, and brain-wide connectivity mapping, to characterize the molecular, anatomical, physiological, and connectional properties of brain cell types in a systematic manner, towards the creation of multi-modal cell atlases for the mouse and human brains. We have now generated a comprehensive and high-resolution transcriptomic and spatial cell type atlas for the whole adult mouse brain, based on the combination of two single-cell-level, whole-brain-scale datasets by scRNA- seq and MERFISH. The atlas is hierarchically organized...

Program Book - Relationship Between Transcriptomics and Connectomics

Mon, 12 Jun 2023 00:00:00 +0000

This conference brings together two cutting-edge domains, transcriptomics and connectomics, and challenges participants to begin thinking seriously about how to approach and analyze the relationship between them. By their very nature, transcriptomics and connectomics deal with complex networks of molecules and neurons, and as such they are catalyzing a revolution in systems neuroscience that may well lead to fundamentally new ways of thinking about the etiology of brain disorders, and about their treatment in terms of novel underlying biological mechanisms. This conference is the first event jointly sponsored by the Center for Neural Circuit Mapping at UCI (https://cncm.som.uci.edu/) and the Cajal Club (https://cajalclub.org/). The Center for Neural Circuit Mapping is in its infancy. ...

Program Book - Linking Brain Function to Cell Types and Circuits

Mon, 12 Jun 2023 00:00:00 +0000

Welcome to our UC Irvine Center for Neural Circuit Mapping (CNCM) 2022 conference on “Linking Brain function to Cell Types and Circuits” at the Beckman Center of the National Academies of Sciences & Engineering. This meeting follows the success of our first in-person 2021 Center conference “Relationship Between Transcriptomics and Connectomics”, jointly sponsored by our Center and the Cajal Club. We decide to host an annual CNCM conference in mid or late August each year; each meeting has a different focus to capture the exciting fast- moving field of neuroscience.