Recent ucm_appliedmath_capstones_2022 items

Analysis of Student Background and Identities at the University of California, Merced

Wed, 27 Aug 2025 00:00:00 +0000

Analysis of Student Background and Identities at the University of California, Merced

Journey from 2D to 3D Biomedical Image Segmentation using Convolutional Neural Networks

Thu, 20 Feb 2025 00:00:00 +0000

Journey from 2D to 3D Biomedical Image Segmentation using Convolutional Neural Networks

Sparse Negative Binomial Signal Recovery for Genomic Variant Prediction in Diploid Species

Wed, 17 Jul 2024 00:00:00 +0000

Sparse Negative Binomial Signal Recovery for Genomic Variant Prediction in Diploid Species

Merging Traditional Scientific Computing with Data Science to Develop New Class of Prediction Engines

Tue, 30 Apr 2024 00:00:00 +0000

Merging Traditional Scientific Computing with Data Science to Develop New Class of Prediction Engines

Mathematical Modeling and Parameter Estimation Uncovers the Role of TFPI in the Regulation of Factor Xa

Wed, 14 Feb 2024 00:00:00 +0000

Blood coagulation is a series of biochemical reactions necessary to form a blood clot upon a vascular injury. The process occurs in three stages (initiation, amplification, and propagation) and in the presence of flow. To regulate bleeding disorders, the clotting system involves inhibition mechanisms at each stage. Initiation in the tissue factor pathway begins when clotting factor VIIa in the plasma binds its cofactor, tissue factor (TF) forming an active enzyme complex (TF:VIIa). Next, clotting factor X in the plasma binds with TF:VIIa and is enzymatically cleaved into activated factor X (Xa). Xa is required for other reactions as coagulation progresses.Tissue factor pathway inhibitor (TFPI) is known to be a strong inhibitor during the initiation phase, with the primary mechanism of binding to Xa in the plasma and then rebinding to TF:VIIa to form the quaternary complex TF:VIIa:Xa:TFPI. However, previous mathematical models of TFPI inhibition predict contradicting results....

Optimal Transport Driven Deep Learning with Emphasis on Pathology Images

Fri, 29 Sep 2023 00:00:00 +0000

Optimal Transport Driven Deep Learning with Emphasis on Pathology Images

A High-throughput Pipeline for the Analysis and Annotation of Sectored Yeast Colonies

Tue, 24 Jan 2023 00:00:00 +0000

A High-throughput Pipeline for the Analysis and Annotation of Sectored Yeast Colonies

Spatial Analysis of Preferential Spread Along Networks

Fri, 29 Apr 2022 00:00:00 +0000

Spatial Analysis of Preferential Spread Along Networks