We consider two copies of the Standard Model, interchanged by an exact parity symmetry, P. The observed fermion mass hierarchy is described by suppression factors ϵni for charged fermion i, as can arise in Froggatt-Nielsen and extra-dimensional theories of flavor. The corresponding flavor factors in the mirror sector are ϵ′ni , so that spontaneous breaking of the parity P arises from a single parameter ϵ′/ϵ, yielding a tightly constrained version of Minimal Mirror Twin Higgs, introduced in our previous paper. Models are studied for simple values of ni, including in particular one with SU(5)-compatibility, that describe the observed fermion mass hierarchy. The entire mirror quark and charged lepton spectrum is broadly predicted in terms of ϵ′/ϵ, as are the mirror QCD scale and the decoupling temperature between the two sectors. Helium-, hydrogen- and neutron-like mirror dark matter candidates are constrained by self-scattering and relic ionization. In each case, the allowed parameter space can be fully probed by proposed direct detection experiments. Correlated predictions are made as well for the Higgs signal strength and the amount of dark radiation.