Motivated by an analysis of the sub-superalgebras of the five-dimensional
superconformal algebra $F(4)$, we search for the holographic duals to
co-dimension one superconformal defects in 5d CFTs which have $SO(4,2) \oplus
U(1)$ bosonic symmetry. In particular, we look for domain wall solutions to
six-dimensional $F(4)$ gauged supergravity coupled to a single vector
multiplet. It is found that supersymmetric domain wall solutions do not exist
unless there is a non-trivial profile for one of the vector multiplet scalars
which is charged under the gauged $SU(2)$ R-symmetry. This non-trivial profile
breaks the $SU(2)$ to $U(1)$, thus matching expectations from the superalgebra
analysis. A consistent set of BPS equations is then obtained and solved
numerically. While the numerical solutions are generically singular and thought
to be dual to boundary CFTs, it is found that for certain fine-tuned choices of
parameters regular Janus solutions may be obtained.