OBJECTIVEdTo better understand the association between diabetes and cognitive impairment, we evaluated macro-and microstructural brain MRI measures for the total brain and regions of interest (ROIs) in a group of community-dwelling elders with and without

Brain-derived neurotrophic factor (BDNF) plays a role in the maintenance and function of neurons. Although persons with Alzheimer's disease have lower cortical levels of BDNF, evidence regarding the association between circulating BDNF and cognitive functi

When data are sparse and/or predictors multicollinear, current implementation of sparse partial least squares (SPLS) does not give estimates for non-selected predictors nor provide a measure of inference. In response, an approach termed "all-possible" SPLS