- Olsen, Rosanna K
- Carr, Valerie A
- Daugherty, Ana M
- La Joie, Renaud
- Amaral, Robert SC
- Amunts, Katrin
- Augustinack, Jean C
- Bakker, Arnold
- Bender, Andrew R
- Berron, David
- Boccardi, Marina
- Bocchetta, Martina
- Burggren, Alison C
- Chakravarty, M Mallar
- Chételat, Gaël
- de Flores, Robin
- DeKraker, Jordan
- Ding, Song-Lin
- Geerlings, Mirjam I
- Huang, Yushan
- Insausti, Ricardo
- Johnson, Elliott G
- Kanel, Prabesh
- Kedo, Olga
- Kennedy, Kristen M
- Keresztes, Attila
- Lee, Joshua K
- Lindenberger, Ulman
- Mueller, Susanne G
- Mulligan, Elizabeth M
- Ofen, Noa
- Palombo, Daniela J
- Pasquini, Lorenzo
- Pluta, John
- Raz, Naftali
- Rodrigue, Karen M
- Schlichting, Margaret L
- Lee Shing, Yee
- Stark, Craig EL
- Steve, Trevor A
- Suthana, Nanthia A
- Wang, Lei
- Werkle-Bergner, Markus
- Yushkevich, Paul A
- Yu, Qijing
- Wisse, Laura EM
- Hippocampal Subfields Group
- et al.
Introduction:Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence. Methods:Our international working group, funded by the EU Joint Programme-Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption. Results:This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures. Discussion:A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.