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Scholarly Works (2 results)

Article
Peer Reviewed

Strong relationship between oral dose and tenofovir hair levels in a randomized trial: Hair as a potential adherence measure for pre-exposure prophylaxis (PrEP)

Gandhi, Monica;
Bacchetti, Peter;
Greenblatt, Ruth;
Grant, Robert;
Liu, AY;
Yang, Q;
Huang, Y;
Anderson, PL;
Jin, C;
Goggin, K;
Stojanovski, K;
Buchbinder, SP

UC San Francisco Previously Published Works (2014)

Background: Pre-exposure prophylaxis (PrEP) trials using tenofovir-based regimens have demonstrated that high levels of adherence are required to evaluate efficacy; the incorporation of objective biomarkers of adherence in trial design has been essential t

Article
Peer Reviewed

Comparing the novel method of assessing PrEP adherence/exposure using hair samples to other pharmacologic and traditional measures

Gandhi, Monica;
Bacchetti, Peter;
Baxi, SM;
Liu, A;
Mutua, G;
Sanders, EJ;
Kibengo, FM;
Haberer, JE;
Rooney, J;
Hendrix, CW;
Anderson, PL

UC San Francisco Previously Published Works (2015)

Copyright © 2014 by Lippincott Williams &Wilkins.Objective: The efficacy of pre-exposure prophylaxis (PrEP) in HIV will diminish with poor adherence; pharmacologic measures of drug exposure have proven critical to PrEP trial interpretation. We assessed dru