- Papa, Feroz;
- Oakes, Scott;
- Wang, L;
- Perera, BGK;
- Hari, SB;
- Bhhatarai, B;
- Backes, BJ;
- Seeliger, MA;
- Schürer, SC;
- Oakes, SA;
- Papa, FR;
- Maly, DJ
Under endoplasmic reticulum stress, unfolded protein accumulation leads to activation of the endoplasmic reticulum transmembrane kinase/endoRNase (RNase) IRE1α. IRE1α oligomerizes, autophosphorylates and initiates splicing of XBP1 mRNA, thus triggering the