- Banza Mpiongo, Patrick;
- Kibanza, Jerry;
- Kambol Yav, Francis;
- Nyombo, Didier;
- Mwepu, Lucie;
- Basame, Djogo;
- Mpoyi, Raoul;
- Madika, Collard;
- Hatton, Trad;
- Mafuta, Eric;
- Gascon, Oriane;
- Tschirhart, Kevin;
- Nkosi, Freddy;
- Lusamba, Paul;
- Merritt, Sydney;
- Mwenda, Julio;
- Tangney, Sylvia;
- Hoff, Nicole;
- Nkamba Mukadi, Dalau;
- Rimoin, Anne;
- Kaba, Didine;
- El Mourid, Amine;
- Senouci, Kamel;
- Ngoie Mwamba, Guillaume;
- Mukamba Musenga, Elisabeth;
- Cikomola, Aimé
BACKGROUND: Low immunization coverage rates in the Democratic Republic of Congo (DRC) have been reflective of challenges with vaccine access, support and delivery in the country. Motivated by measles and vaccine-derived polio virus (VDPV) outbreaks in 2016-17 and low vaccination rates, the provinces of Haut Lomami and Tanganyika were identified as pilot locations for an innovative approach focused on establishing a consortium of partners supporting local government. This approach was formalized through Memorandums of Understanding (MoUs) between the Bill and Melinda Gates Foundation and Provincial governments in 2018. A third province, Lualaba, established an MoU in 2021. MOU IMPLEMENTATION: These MoUs were 5-year partnerships designed to aid provinces in meeting four key objectives: 80 % immunization coverage, management/elimination of polio/cVDPV outbreaks, improvement of vaccine accessibility, and transfer of immunization service management to provincial leadership. OUTCOMES: During the MoU period, Haut-Lomami saw an increase in full immunization coverage, from 35.7 % (MICS 2018) to 88.9 % (VCS 2021-22), the highest in country. A sharp drop in percentage of zero-dose children was observed in the 3 provinces, confirming improved access to immunization services. Tanganyika saw initial improvement in full immunization coverage, followed by a drop in the VCS 2021-22 due to COVID-19 and healthcare worker strikes. Coverage improved in Tanganyika in the 2023 VCS. The 3 provinces increased their financial contributions to routine immunization and are now the top contributing provinces. While no cVDPV cases were recorded in 2020 and 2021, cVDPV1 and cVDPV2 outbreaks are afflicting the 3 provinces since 2022. CONCLUSIONS: Ultimately, the provincial MoUs were successful in bolstering provincial autonomy and capacity building with the biggest success being a drop in zero-dose children. While not all objectives have been met, the MoU approach served as an innovative program for key aspects of strengthening routine immunization in the DRC.