• Post-partum depression (PPD) affects 1 in 8 women
• PPD has consequences for both mother and child
• Negatively impacts breastfeeding, sleep routines, well-child visits, vaccinations, and safety practices
• Until recently, the primary treatment for PPD has been psychotherapy and antidepressants
• Brexanolone (generic for Zulresso) was FDA approved March 2019 and is the first drug approved specifically for PPD
• 60-hour IV infusion
• Neurosteroid and analogue of allopregnanolone
• This medication offers a novel approach to treatment of postpartum depression