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Scholarly Works (1 results)

Article
Peer Reviewed

Identifying and quantifying heterogeneity in high content analysis: Application of heterogeneity indices to drug discovery

Grandis, Jennifer;
Gough, AH;
Chen, N;
Shun, TY;
Lezon, TR;
Boltz, RC;
Reese, CE;
Wagner, J;
Vernetti, LA;
Grandis, JR;
Lee, AV

UC San Francisco Previously Published Works (2014)

One of the greatest challenges in biomedical research, drug discovery and diagnostics is understanding how seemingly identical cells can respond differently to perturbagens including drugs for disease treatment. Although heterogeneity has become an accepte