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Scholarly Works (1 results)

Article
Peer Reviewed

Flipping in the pore: Discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant s31n mutant of the influenza a virus m2 proton channel

Degrado, William;
Wu, Y;
Canturk, B;
Jo, H;
Ma, C;
Gianti, E;
Klein, ML;
Pinto, LH;
Lamb, RA;
Fiorin, G;
Wang, J

UC San Francisco Previously Published Works (2014)

© 2014 American Chemical Society.Influenza virus infections lead to numerous deaths and millions of hospitalizations each year. One challenge facing anti-influenza drug development is the heterogeneity of the circulating influenza viruses, which comprise s