The impacts on global climate of the AD 536 and 541 volcanic eruptions are well attested in palaeoclimatic datasets and in Eurasian historical records. Their effects on farmers in the arid uplands of western North America, however, remain poorly understood. The authors investigate whether extreme cold caused by these eruptions influenced the scale, scope and timing of the Neolithic Transition in the northern US Southwest. Archaeological tree-ring and radiocarbon dates, along with settlement survey data, suggest that extreme cooling generated the physical and social space that enabled early farmers to transition from kin-focused socio-economic strategies to increasingly complex and widely shared forms of social organisation that served as foundational elements of burgeoning Ancestral Pueblo societies.