Fully spin delocalized mixed valence copper-sulfur clusters, 1 and 2, supported by μ₄-sulfido and NS^thiol donor ligands are synthesized and characterized. Wheel shaped 1 consists of Cu₂S₂ units. The unprecedented nanoball 2 can be described as S@Cu₄(tetrahedron)@O₆(octahedron)@Cu₁₂S₁₂(cage) consisting of both Cu₂S₂ and (μ₄-S)Cu₄ units. The Cu₂S₂ and (μ₄-S)Cu₄ units resemble biological Cu_A and Cu_Z sites respectively.