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Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

Morgan, David;
Lu, D;
Hsiao, JY;
Davey, NE;
van, VA;
Foster, SA;
Tang, C;
Morgan, DO

UC San Francisco Previously Published Works (2014)

© 2014 Lu et al.The ubiquitin protein ligase anaphase-promoting complex or cyclosome (APC/C) controls mitosis by promoting ordered degradation of securin, cyclins, and other proteins. The mechanisms underlying the timing of APC/C substrate degradation are