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Scholarly Works (2 results)

Article
Peer Reviewed

Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia

Verkman, Alan;
Veit, G;
Bossard, F;
Goepp, J;
Verkman, AS;
Galietta, LJV;
Hanrahan, JW;
Lukacs, GL

UC San Francisco Previously Published Works (2012)

Cystic fibrosis (CF) is caused by the functional expression defect of the CF transmembrane conductance regulator (CFTR) chloride channel at the apical plasma membrane. Impaired bacterial clearance and hyperactive innate immune response are hallmarks of the

Article
Peer Reviewed

Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice.

Rock, Jason;
Maurya, DK;
Henriques, T;
Marini, M;
Pedemonte, N;
Galietta, LJV;
Rock, JR;
Harfe, BD;
Menini, A

UC San Francisco Previously Published Works (2015)

TMEM16A/ANO1 is a calcium-activated chloride channel expressed in several types of epithelia and involved in various physiological processes, including proliferation and development. During mouse embryonic development, the expression of TMEM16A in the olfa