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Scholarly Works (5 results)
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Article
Collide-oscope II
Green, Anthony R.
Contemporary Music Score Collection
(2020)
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
Article
To Anacreon in the US
Green, Anthony R.
Contemporary Music Score Collection
(2020)
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
Article
Collide-oscope V
Green, Anthony R.
Contemporary Music Score Collection
(2020)
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
Article
Peer Reviewed
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Ju, Young Seok
;
Tubio, Jose MC
;
Mifsud, William
;
Fu, Beiyuan
;
Davies, Helen R
;
Ramakrishna, Manasa
;
Li, Yilong
;
Yates, Lucy
;
Gundem, Gunes
;
Tarpey, Patrick S
;
Behjati, Sam
;
Papaemmanuil, Elli
;
Martin, Sancha
;
Fullam, Anthony
;
Gerstung, Moritz
;
Group, ICGC Prostate Cancer Working
;
Group, ICGC Bone Cancer Working
;
Group, ICGC Breast Cancer Working
;
Nangalia, Jyoti
;
Green, Anthony R
;
Caldas, Carlos
;
Borg, Åke
;
Tutt, Andrew
;
Lee, Ming Ta Michael
;
Veer, Laura J van't
;
Tan, Benita KT
;
Aparicio, Samuel
;
Span, Paul N
;
Martens, John WM
;
Knappskog, Stian
;
Vincent-Salomon, Anne
;
Børresen-Dale, Anne-Lise
;
Eyfjörd, Jórunn Erla
;
Flanagan, Adrienne M
;
Foster, Christopher
;
Neal, David E
;
Cooper, Colin
;
Eeles, Rosalind
;
Lakhani, Sunil R
;
Desmedt, Christine
;
Thomas, Gilles
;
Richardson, Andrea L
;
Purdie, Colin A
;
Thompson, Alastair M
;
McDermott, Ultan
;
Yang, Fengtang
;
Nik-Zainal, Serena
;
Campbell, Peter J
;
Stratton, Michael R
UC San Francisco Previously Published Works
(2015)
Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm, and the mitochondrial double membrane. Despite these physical barriers, we show that somatically acquired mitochondrial-nuclear genome fusion sequences are present in cancer cells. Most occur in conjunction with intranuclear genomic rearrangements, and the features of the fusion fragments indicate that nonhomologous end joining and/or replication-dependent DNA double-strand break repair are the dominant mechanisms involved. Remarkably, mitochondrial-nuclear genome fusions occur at a similar rate per base pair of DNA as interchromosomal nuclear rearrangements, indicating the presence of a high frequency of contact between mitochondrial and nuclear DNA in some somatic cells. Transmission of mitochondrial DNA to the nuclear genome occurs in neoplastically transformed cells, but we do not exclude the possibility that some mitochondrial-nuclear DNA fusions observed in cancer occurred years earlier in normal somatic cells.
Article
Peer Reviewed
International network of cancer genome projects
Hudson (Chairperson), Thomas J
;
Anderson, Warwick
;
Aretz, Axel
;
Barker, Anna D
;
Bell, Cindy
;
Bernabé, Rosa R
;
Bhan, MK
;
Calvo, Fabien
;
Eerola, Iiro
;
Gerhard, Daniela S
;
Guttmacher, Alan
;
Guyer, Mark
;
Hemsley, Fiona M
;
Jennings, Jennifer L
;
Kerr, David
;
Klatt, Peter
;
Kolar, Patrik
;
Kusuda, Jun
;
Lane, David P
;
Laplace, Frank
;
Lu, Youyong
;
Nettekoven, Gerd
;
Ozenberger, Brad
;
Peterson, Jane
;
Rao, TS
;
Remacle, Jacques
;
Schafer, Alan J
;
Shibata, Tatsuhiro
;
Stratton, Michael R
;
Vockley, Joseph G
;
Watanabe, Koichi
;
Yang, Huanming
;
Yuen, Matthew MF
;
Knoppers (Leader), Bartha M
;
Bobrow, Martin
;
Cambon-Thomsen, Anne
;
Dressler, Lynn G
;
Dyke, Stephanie OM
;
Joly, Yann
;
Kato, Kazuto
;
Kennedy, Karen L
;
Nicolás, Pilar
;
Parker, Michael J
;
Rial-Sebbag, Emmanuelle
;
Romeo-Casabona, Carlos M
;
Shaw, Kenna M
;
Wallace, Susan
;
Wiesner, Georgia L
;
Zeps, Nikolajs
;
Lichter (Leader), Peter
;
Biankin, Andrew V
;
Chabannon, Christian
;
Chin, Lynda
;
Clément, Bruno
;
de Alava, Enrique
;
Degos, Françoise
;
Ferguson, Martin L
;
Geary, Peter
;
Hayes, D Neil
;
Hudson, Thomas J
;
Johns, Amber L
;
Kasprzyk, Arek
;
Nakagawa, Hidewaki
;
Penny, Robert
;
Piris, Miguel A
;
Sarin, Rajiv
;
Scarpa, Aldo
;
Shibata, Tatsuhiro
;
van de Vijver, Marc
;
Futreal (Leader), P Andrew
;
Aburatani, Hiroyuki
;
Bayés, Mónica
;
Bowtell, David DL
;
Campbell, Peter J
;
Estivill, Xavier
;
Gerhard, Daniela S
;
Grimmond, Sean M
;
Gut, Ivo
;
Hirst, Martin
;
López-Otín, Carlos
;
Majumder, Partha
;
Marra, Marco
;
McPherson, John D
;
Nakagawa, Hidewaki
;
Ning, Zemin
;
Puente, Xose S
;
Ruan, Yijun
;
Shibata, Tatsuhiro
;
Stratton, Michael R
;
Stunnenberg, Hendrik G
;
Swerdlow, Harold
;
Velculescu, Victor E
;
Wilson, Richard K
;
Xue, Hong H
;
Yang, Liu
;
Spellman (Leader), Paul T
;
Bader, Gary D
;
Boutros, Paul C
;
Campbell, Peter J
;
Flicek, Paul
;
Getz, Gad
;
Guigó, Roderic
;
Guo, Guangwu
;
Haussler, David
;
Heath, Simon
;
Hubbard, Tim J
;
Jiang, Tao
;
Jones, Steven M
;
Li, Qibin
;
López-Bigas, Nuria
;
Luo, Ruibang
;
Muthuswamy, Lakshmi
;
Francis Ouellette, BF
;
Pearson, John V
;
Puente, Xose S
;
Quesada, Victor
;
Raphael, Benjamin J
;
Sander, Chris
;
Shibata, Tatsuhiro
;
Speed, Terence P
;
Stein, Lincoln D
;
Stuart, Joshua M
;
Teague, Jon W
;
Totoki, Yasushi
;
Tsunoda, Tatsuhiko
;
Valencia, Alfonso
;
Wheeler, David A
;
Wu, Honglong
;
Zhao, Shancen
;
Zhou, Guangyu
;
Stein (Leader), Lincoln D
;
Guigó, Roderic
;
Hubbard, Tim J
;
Joly, Yann
;
Jones, Steven M
;
Kasprzyk, Arek
;
Lathrop, Mark
;
López-Bigas, Nuria
;
Francis Ouellette, BF
;
Spellman, Paul T
;
Teague, Jon W
;
Thomas, Gilles
;
Valencia, Alfonso
;
Yoshida, Teruhiko
;
Kennedy (Leader), Karen L
;
Axton, Myles
;
Dyke, Stephanie OM
;
Futreal, P Andrew
;
Gerhard, Daniela S
;
Gunter, Chris
;
Guyer, Mark
;
Hudson, Thomas J
;
McPherson, John D
;
Miller, Linda J
;
Ozenberger, Brad
;
Shaw, Kenna M
;
Kasprzyk (Leader), Arek
;
Stein (Leader), Lincoln D
;
Zhang, Junjun
;
Haider, Syed A
;
Wang, Jianxin
;
Yung, Christina K
;
Cross, Anthony
;
Liang, Yong
;
Gnaneshan, Saravanamuttu
;
Guberman, Jonathan
;
Hsu, Jack
;
Bobrow (Leader), Martin
;
Chalmers, Don RC
;
Hasel, Karl W
;
Joly, Yann
;
Kaan, Terry SH
;
Kennedy, Karen L
;
Knoppers, Bartha M
;
Lowrance, William W
;
Masui, Tohru
;
Nicolás, Pilar
;
Rial-Sebbag, Emmanuelle
;
Lyman Rodriguez, Laura
;
Vergely, Catherine
;
Yoshida, Teruhiko
;
Grimmond (Leader), Sean M
;
Biankin, Andrew V
;
Bowtell, David DL
;
Cloonan, Nicole
;
deFazio, Anna
;
Eshleman, James R
;
Etemadmoghadam, Dariush
;
Gardiner, Brooke A
;
Kench, James G
;
Scarpa, Aldo
;
Sutherland, Robert L
;
Tempero, Margaret A
;
Waddell, Nicola J
;
Wilson, Peter J
;
McPherson (Leader), John D
;
Gallinger, Steve
;
Tsao, Ming-Sound
;
Shaw, Patricia A
;
Petersen, Gloria M
;
Mukhopadhyay, Debabrata
;
Chin, Lynda
;
DePinho, Ronald A
;
Thayer, Sarah
;
Muthuswamy, Lakshmi
;
Shazand, Kamran
;
Beck, Timothy
;
Sam, Michelle
;
Timms, Lee
;
Ballin, Vanessa
;
Lu (Leader), Youyong
;
Ji, Jiafu
;
Zhang, Xiuqing
;
Chen, Feng
;
Hu, Xueda
;
Zhou, Guangyu
;
Yang, Qi
;
Tian, Geng
;
Zhang, Lianhai
;
Xing, Xiaofang
;
Li, Xianghong
;
Zhu, Zhenggang
;
Yu, Yingyan
;
Yu, Jun
;
Yang, Huanming
;
Lathrop (Leader), Mark
;
Tost, Jörg
;
Brennan, Paul
;
Holcatova, Ivana
;
Zaridze, David
;
Brazma, Alvis
;
Egevad, Lars
;
Prokhortchouk, Egor
;
Elizabeth Banks, Rosamonde
;
Uhlén, Mathias
;
Cambon-Thomsen, Anne
;
Viksna, Juris
;
Ponten, Fredrik
;
Skryabin, Konstantin
;
Stratton (Leader), Michael R
;
Futreal, P Andrew
;
Birney, Ewan
;
Borg, Ake
;
Børresen-Dale, Anne-Lise
;
Caldas, Carlos
;
Foekens, John A
;
Martin, Sancha
;
Reis-Filho, Jorge S
;
Richardson, Andrea L
;
Sotiriou, Christos
;
Stunnenberg, Hendrik G
;
Thomas, Gilles
;
van de Vijver, Marc
;
van’t Veer, Laura
;
Calvo (Leader), Fabien
;
Birnbaum, Daniel
;
Blanche, Hélène
;
Boucher, Pascal
;
Boyault, Sandrine
;
Chabannon, Christian
;
Gut, Ivo
;
Masson-Jacquemier, Jocelyne D
;
Lathrop, Mark
;
Pauporté, Iris
;
Pivot, Xavier
;
Vincent-Salomon, Anne
;
Tabone, Eric
;
Theillet, Charles
;
Thomas, Gilles
;
Tost, Jörg
;
Treilleux, Isabelle
;
Calvo (Leader), Fabien
;
Bioulac-Sage, Paulette
;
Clément, Bruno
;
Decaens, Thomas
;
Degos, Françoise
;
Franco, Dominique
;
Gut, Ivo
;
Gut, Marta
;
Heath, Simon
;
Lathrop, Mark
;
Samuel, Didier
;
Thomas, Gilles
;
Zucman-Rossi, Jessica
;
Lichter (Leader), Peter
;
Eils (Leader), Roland
;
Brors, Benedikt
;
Korbel, Jan O
;
Korshunov, Andrey
;
Landgraf, Pablo
;
Lehrach, Hans
;
Pfister, Stefan
;
Radlwimmer, Bernhard
;
Reifenberger, Guido
;
Taylor, Michael D
;
von Kalle, Christof
;
Majumder (Leader), Partha P
;
Sarin, Rajiv
;
Rao, TS
;
Bhan, MK
;
Scarpa (Leader), Aldo
;
Pederzoli, Paolo
;
Lawlor, Rita T
;
Delledonne, Massimo
;
Bardelli, Alberto
;
Biankin, Andrew V
;
Grimmond, Sean M
;
Gress, Thomas
;
Klimstra, David
;
Zamboni, Giuseppe
;
Shibata (Leader), Tatsuhiro
;
Nakamura, Yusuke
;
Nakagawa, Hidewaki
;
Kusuda, Jun
;
Tsunoda, Tatsuhiko
;
Miyano, Satoru
;
Aburatani, Hiroyuki
;
Kato, Kazuto
;
Fujimoto, Akihiro
;
Yoshida, Teruhiko
;
Campo (Leader), Elias
;
López-Otín, Carlos
;
Estivill, Xavier
;
Guigó, Roderic
;
de Sanjosé, Silvia
;
Piris, Miguel A
;
Montserrat, Emili
;
González-Díaz, Marcos
;
Puente, Xose S
;
Jares, Pedro
;
Valencia, Alfonso
;
Himmelbaue, Heinz
;
Quesada, Victor
;
Bea, Silvia
;
Stratton (Leader), Michael R
;
Futreal, P Andrew
;
Campbell, Peter J
;
Vincent-Salomon, Anne
;
Richardson, Andrea L
;
Reis-Filho, Jorge S
;
van de Vijver, Marc
;
Thomas, Gilles
;
Masson-Jacquemier, Jocelyne D
;
Aparicio, Samuel
;
Borg, Ake
;
Børresen-Dale, Anne-Lise
;
Caldas, Carlos
;
Foekens, John A
;
Stunnenberg, Hendrik G
;
van’t Veer, Laura
;
Easton, Douglas F
;
Spellman, Paul T
;
Martin, Sancha
;
Barker, Anna D
;
Chin, Lynda
;
Collins, Francis S
;
Compton, Carolyn C
;
Ferguson, Martin L
;
Gerhard, Daniela S
;
Getz, Gad
;
Gunter, Chris
;
Guttmacher, Alan
;
Guyer, Mark
;
Hayes, D Neil
;
Lander, Eric S
;
Ozenberger, Brad
;
Penny, Robert
;
Peterson, Jane
;
Sander, Chris
;
Shaw, Kenna M
;
Speed, Terence P
;
Spellman, Paul T
;
Vockley, Joseph G
;
Wheeler, David A
;
Wilson, Richard K
;
Hudson (Chairperson), Thomas J
;
Chin, Lynda
;
Knoppers, Bartha M
;
Lander, Eric S
;
Lichter, Peter
;
Stein, Lincoln D
;
Stratton, Michael R
;
Anderson, Warwick
;
Barker, Anna D
;
Bell, Cindy
;
Bobrow, Martin
;
Burke, Wylie
;
Collins, Francis S
;
Compton, Carolyn C
;
DePinho, Ronald A
;
Easton, Douglas F
;
Futreal, P Andrew
;
Gerhard, Daniela S
;
Green, Anthony R
;
Guyer, Mark
;
Hamilton, Stanley R
;
Hubbard, Tim J
;
Kallioniemi, Olli P
;
Kennedy, Karen L
;
Ley, Timothy J
;
Liu, Edison T
;
Lu, Youyong
;
Majumder, Partha
;
Marra, Marco
;
Ozenberger, Brad
;
Peterson, Jane
;
Schafer, Alan J
;
Spellman, Paul T
;
Stunnenberg, Hendrik G
;
Wainwright, Brandon J
;
Wilson, Richard K
;
Yang, Huanming
UCLA Previously Published Works
(2010)
The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
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