The hot Jupiter HD 209458b is particularly amenable to detailed study as it is among the brightest transiting exoplanet systems currently known (V-mag = 7.65; K-mag = 6.308) and has a large planet-to-star contrast ratio. HD 209458b is predicted to be in synchronous rotation about its host star with a hot spot that is shifted eastward of the substellar point by superrotating equatorial winds. Here we present the first full-orbit observations of HD 209458b, in which its 4.5 μm emission was recorded with Spitzer/IRAC. Our study revises the previous 4.5 μm measurement of HD 209458b's secondary eclipse emission downward by 35% to , changing our interpretation of the properties of its dayside atmosphere. We find that the hot spot on the planet's dayside is shifted eastward of the substellar point by 40.°9 ± 6.°0, in agreement with circulation models predicting equatorial superrotation. HD 209458b's dayside (T bright = 1499 ± 15 K) and nightside (T bright = 972 ± 44 K) emission indicate a day-to-night brightness temperature contrast smaller than that observed for more highly irradiated exoplanets, suggesting that the day-to-night temperature contrast may be partially a function of the incident stellar radiation. The observed phase curve shape deviates modestly from global circulation model predictions potentially due to disequilibrium chemistry or deficiencies in the current hot CH4 line lists used in these models. Observations of the phase curve at additional wavelengths are needed in order to determine the possible presence and spatial extent of a dayside temperature inversion, as well as to improve our overall understanding of this planet's atmospheric circulation. © 2014. The American Astronomical Society. All rights reserved..