Illinois is home to the sixth largest Asian American and Pacific Islander (AAPI) population nationwide. AAPIs suffer higher incidence, morbidity, and mortality rates from certain cancers, infectious, and chronic diseases. Despite the exponential growth of the AAPI population, few state-level data sources exist that provide detailed and accurate information regarding AAPI health disparities and needs. Efforts to improve health care for this population will require improved data collection and funding for research on AAPI ethnic groups.