- Krogan, Nevan;
- Farese, Robert;
- Finkbeiner, Steven;
- Armakola, M;
- Higgins, MJ;
- Figley, MD;
- Barmada, SJ;
- Scarborough, EA;
- Diaz, Z;
- Fang, X;
- Shorter, J;
- Krogan, NJ
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease primarily affecting motor neurons. Mutations in the gene encoding TDP-43 cause some forms of the disease, and cytoplasmic TDP-43 aggregates accumulate in degenerating neurons of