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Scholarly Works (2 results)

Article
Peer Reviewed

Large-Scale Determination of Sequence, Structure, and Function Relationships in Cytosolic Glutathione Transferases across the Biosphere

Babbitt, Patricia;
Mashiyama, ST;
Malabanan, MM;
Akiva, E;
Bhosle, R;
Branch, MC;
Hillerich, B;
Jagessar, K;
Kim, J;
Patskovsky, Y;
Seidel, RD

UC San Francisco Previously Published Works (2014)

The cytosolic glutathione transferase (cytGST) superfamily comprises more than 13,000 nonredundant sequences found throughout the biosphere. Their key roles in metabolism and defense against oxidative damage have led to thousands of studies over several de

Article
Peer Reviewed

Functional annotation and structural characterization of a novel lactonase hydrolyzing d-xylono-1,4-lactone-5-phosphate and l -arabino-1,4-lactone-5- phosphate

Shoichet, Brian;
Korczynska, M;
Xiang, DF;
Zhang, Z;
Xu, C;
Narindoshvili, T;
Kamat, SS;
Williams, HJ;
Chang, SS;
Kolb, P;
Hillerich, B

UC San Francisco Previously Published Works (2014)

A novel lactonase from Mycoplasma synoviae 53 (MS53-0025) and Mycoplasma agalactiae PG2 (MAG-6390) was characterized by protein structure determination, molecular docking, gene context analysis, and library screening. The crystal structure of MS53-0025 was