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Article
Peer Reviewed

Prolonged Tracheal Intubation and the Association Between Patent Ductus Arteriosus and Bronchopulmonary Dysplasia: A Secondary Analysis of the PDA-TOLERATE trial

Clyman, Ronald I;
Kaempf, Joseph;
Liebowitz, Melissa;
Erdeve, Omer;
Bulbul, Ali;
Håkansson, Stellan;
Lindqvist, Johanna;
Farooqi, Aijaz;
Katheria, Anup;
Sauberan, Jason;
Singh, Jaideep;
Nelson, Kelly;
Wickremasinghe, Andrea;
Dong, Lawrence;
Hassinger, Denise C;
Aucott, Susan W;
Hayashi, Madoka;
Heuchan, Anne Marie;
Carey, William A;
Derrick, Matthew;
Fernandez, Erika;
Sankar, Meera;
Leone, Tina;
Perez, Jorge;
Serize, Arturo;
Investigators, the PDA-TOLERATE Trial;
Fields, Scott;
Whitten, Lora;
Rogers, Stefanie;
Okulu, Emel;
Tunc, Gaffari;
Ucar, Tayfun;
Ünal, Ebru Türkoglu;
Steen, Jane;
Arnell, Kathy;
Holtschlag, Sarah;
Schreiber, Michael;
Peters, Caryn;
Gilmore, Maureen;
McKay, Lorna;
Carole, Dianne;
Shaw, Annette;
Harris, Malinda;
Amsbaugh, Amy;
Liedl, Lavonne M;
Wolf, Sue;
Groner, Avi;
Kimball, Amy;
Kim, Jae;
Bridge, Renee;
Knodel, Ellen;
Weng, Chrissy;
Barbosa, Magaly Diaz;
Polin, Richard;
Weindler, Marilyn;
Noori, Shahab;
Reese, Jeffrey;
Sun, Yao

UC San Francisco Previously Published Works (2021)

In the PDA-TOLERATE trial, persistent (even for several weeks) moderate to large patent ductus arteriosus (PDA) was not associated with an increased risk of BPD when the infant required <10 days of intubation. However, in infants requiring intubation for ≥10 days, prolonged PDA exposure (≥11 days) was associated with an increased risk of moderate/severe BPD.

Cover page: Prolonged Tracheal Intubation and the Association Between Patent Ductus Arteriosus and Bronchopulmonary Dysplasia: A Secondary Analysis of the PDA-TOLERATE trial