In this dissertation, a search for New Physics is presented in proton-proton collisions at sqrt(s) = 13 TeV. This collision data was collected by the Compact
Muon Solenoid detector at the CERN Large Hadron Collider located in Geneva, Switzerland in 2015 and corresponds to an integrated luminosity of 2.3 fb^−1. The search analyzes events with zero leptons and large hadronic activity. The data is divided into search regions of jet multiplicity, bottom quark tagged jet multiplicity, missing transverse momentum, and scalar sum of jet transverse momenta. The observed event count in the search regions are found to be in agreement within the standard model expectation. Thus, the results are interpreted in the context of simplified supersymmetric models of gluino pair production leading to a significant improvement in the exclusion limits on the possible mass of the gluino and neutralino.