Purpose
To report endothelial corneal graft rejection after administration of topical latanoprost eye drops.Case report
Two eyes of two patients with a history of multiple intraocular procedures prior to penetrating keratoplasty developed endothelial graft rejection one month after administration of topical latanoprost. Cystoid macular edema developed simultaneously in one patient.Conclusion
Latanoprost may trigger endothelial graft rejection in susceptible eyes.