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Scholarly Works (32 results)
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Article
Peer Reviewed
SP323EFFECTS OF RVX-208, A FIRST IN CLASS EPIGENETIC BET INHIBITOR, ON KEY RENAL PARAMETERS IN SUBJECTS WITH A HISTORY OF CVD, AND CHRONIC KIDNEY DISEASE (CKD); A POST-HOC ANALYSIS OF PATIENTS FROM THE ASSERT, SUSTAIN AND ASSURE CLINICAL TRIALS
Kalantar-Zadeh, Kamyar
;
Johansson, Jan
;
Lebioda, Ken
;
Halliday, Christopher
;
Sweeney, Michael
;
Wong, Norman
UC Irvine Previously Published Works
(2015)
Article
Peer Reviewed
EFFECTS OF APABETALONE (RVX-208) ON SERUM ALBUMIN IN SUBJECTS WITH CVD, DIABETES AND CHRONIC KIDNEY DISEASE; A POST-HOC ANALYSIS OF THE ASSURE AND SUSTAIN CLINICAL TRIALS
Kulikowski, Ewelina
;
Halliday, Christopher
;
Lebioda, Ken
;
Johansson, Jan
;
Sweeney, Mike
;
Kalantar-Zadeh, Kam
UC Irvine Previously Published Works
(2017)
Article
Peer Reviewed
SP071APABETALONE (RVX-208), A SELECTIVE BROMODOMAIN AND EXTRA-TERMINAL (BET) PROTEIN INHIBITOR, DECREASES ABUNDANCE AND ACTIVITY OF COMPLEMENT PROTEINS IN VITRO, IN MICE AND IN CLINICAL STUDIES
Wong, Norman Cw
;
Kalantar-Zadeh, Kamyar
;
Kulikowski, Ewelina
;
Wasiak, Sylwia
;
Gilham, Dean
;
Halliday, Christopher
;
Sweeney, Mike
;
Johansson, Jan
UC Irvine Previously Published Works
(2016)
Article
Peer Reviewed
DESIGN FEATURES OF THE BETONMACE CHRONIC KIDNEY DISEASE SUB-STUDY; EFFECTS OF THE SELECTIVE BET-INHIBITOR APABETALONE ON KIDNEY FUNCTION AND MACE IN POST-ACS PATIENTS WITH ESTIMATED GLOMERULAR FILTRATION RATE BELOW 60 AND DIABETES
Kalantar-Zadeh, Kam
;
Johansson, Jan
;
Kulikowski, Ewelina
;
Halliday, Christopher
;
Lebioda, Ken
;
Sweeney, Mike
;
Wong, Norman
;
Nicholls, Stephen
;
Schwartz, Gregory
;
Ray, Kausik
UC Irvine Previously Published Works
(2018)
Article
Peer Reviewed
APABETALONE (RVX-208) IMPACTS KEY BIOMARKERS AND PATHWAYS ASSOCIATED WITH CHRONIC KIDNEY DISEASE IN PATIENTS WITH SEVERE RENAL IMPAIRMENT
Kulikowski, Ewelina
;
Wasiak, Sylwia
;
Tsujikawa, Laura
;
Gilham, Dean
;
Halliday, Christopher
;
Rakai, Brooke
;
Jahagirdar, Ravi
;
Kalantar-Zadeh, Kam
;
Sweeney, Mike
;
Johansson, Jan
;
Wong, Norman
;
Robson, Richard
UC Irvine Previously Published Works
(2017)
Article
Peer Reviewed
INHIBITION OF BET PROTEINS WITH APABETALONE REDUCES MEDIATORS OF VASCULAR CALCIFICATION IN VITRO AND IN CKD PATIENTS
Gilham, Dean
;
Tsujikawa, Laura
;
Wasiak, Sylwia
;
Halliday, Chris
;
Sarsons, Chris
;
Stotz, Stephanie
;
Kalantar-Zadeh, Kam
;
Jahagirdar, Ravi
;
Johansson, Jan
;
Wong, Norman
;
Sweeney, Mike
;
Robson, Richard
;
Kulikowski, Ewelina
UC Irvine Previously Published Works
(2018)
Article
Peer Reviewed
Effect of BET Protein Inhibition With Apabetalone on Cardiovascular Outcomes in Patients With Acute Coronary Syndrome and Diabetes - Results of the BETonMACE Trial
Ray, Kausik K
;
Nicholls, Stephen J
;
Ginsberg, Henry N
;
Johansson, Jan O
;
Kalantar-Zadeh, Kamyar
;
Kulikowski, Ewelina
;
Toth, Peter P
;
Wong, Norman
;
Sweeney, Michael
;
Schwartz, Gregory G
UC Irvine Previously Published Works
(2019)
Article
Peer Reviewed
Cardiovascular Evaluation of the Selective BET Inhibitor, Apabetalone, in ACS Patients With Diabetes: Baseline Characteristics of the BETonMACE CV Outcomes Study
Ray, Kausik K
;
Nicholls, Stephen J
;
Sweeney, Mike
;
Johansson, Jan O
;
Toth, Peter P
;
Ginsberg, Henry
;
Kalantar-Zadeh, Kamyar
;
Schwartz, Gregory G
UC Irvine Previously Published Works
(2018)
Article
Peer Reviewed
THE BET PROTEIN INHIBITOR APABETALONE REDUCES CONGESTIVE HEART FAILURE INCIDENCE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND DIABETES: RESULTS FROM THE BETONMACE TRIAL
Sweeney, Michael
;
Nicholls, Stephen J
;
Ray, Kausik Kumar
;
Buhr, Kevin
;
Ginsberg, Henry
;
Johansson, Jan
;
Kalantar-Zadeh, Kamyar
;
Kulikowski, Ewelina
;
Toth, Peter
;
Wong, Norman
;
Schwartz, Gregory G
UC Irvine Previously Published Works
(2020)
Article
Peer Reviewed
APABETALONE, A BROMODOMAIN AND EXTRATERMINAL PROTEIN INHIBITOR, DECREASES KEY FACTORS IN VASCULAR CALCIFICATION IN VITRO AND IN CLINICAL TRIALS
Kulikowski, Ewelina
;
Gilham, Dean
;
Tsujikawa, Laura
;
Wasiak, Sylwia
;
Halliday, Christopher
;
Rakai, Brooke
;
Kalantar-Zadeh, Kam
;
Jahagirdar, Ravi
;
Sweeney, Mike
;
Johansson, Jan
;
Wong, Norman
;
Robson, Richard
UC Irvine Previously Published Works
(2017)
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