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Article
Peer Reviewed

ShcA Protects against Epithelial–Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

Akhurst, Rosemary;
Muthusamy, BP;
Budi, EH;
Katsuno, Y;
Lee, MK;
Smith, SM;
Mirza, AM;
Akhurst, RJ;
Derynck, R

UC San Francisco Previously Published Works (2015)

© 2015 Muthusamy et al.Epithelial–mesenchymal transition (EMT) is a normal cell differentiation event during development and contributes pathologically to carcinoma and fibrosis progression. EMT often associates with increased transforming growth factor-β